D. Lecca

发表

Role of chronic neuroinflammation in neuroplasticity and cognitive function: A hypothesis

N. Greig, Yazhou Li, R. McDevitt, 2022, Alzheimer's & dementia : the journal of the Alzheimer's Association.

Dynamic changes in pro- and anti-inflammatory cytokines in microglia after PPAR-γ agonist neuroprotective treatment in the MPTPp mouse model of progressive Parkinson's disease

G. Simbula, A. Carta, S. Spiga, 2014, Neurobiology of Disease.

3,6’-dithiopomalidomide reduces neural loss, inflammation, behavioral deficits in brain injury and microglial activation

N. Greig, B. Hoffer, Dong Seok Kim, 2020, eLife.

Neuroprotective and anti-inflammatory properties of a novel non-thiazolidinedione PPARγ agonist in vitro and in MPTP-treated mice

M. Casu, D. K. Nevin, A. Carta, 2015, Neuroscience.

Boosting phagocytosis and anti‐inflammatory phenotype in microglia mediates neuroprotection by PPARγ agonist MDG548 in Parkinson's disease models

M. Casu, G. Simbula, E. Janda, 2018, British journal of pharmacology.

3,6′- and 1,6′-Dithiopomalidomide Mitigate Ischemic Stroke in Rats and Blunt Inflammation

N. Greig, Dong Seok Kim, W. Selman, 2022, Pharmaceutics.

Activity of a Novel Anti-Inflammatory Agent F-3,6′-dithiopomalidomide as a Treatment for Traumatic Brain Injury

N. Greig, Dong Seok Kim, W. Selman, 2022, Biomedicines.

Microglia Drive Pockets of Neuroinflammation in Middle Age

N. Greig, D. Saban, D. Tweedie, 2021, The Journal of Neuroscience.

Neuroprotective and immunomodulatory properties of the new PPARγ agonist MDG548: an in vitro and in vivo study in PD models

D. Lecca, 2016 .

Differential induction of dyskinesia and neuroinflammation by pulsatile versus continuous l-DOPA delivery in the 6-OHDA model of Parkinson's disease

E. Carboni, G. Cossu, S. Fenu, 2016, Experimental Neurology.

(-)-Phenserine and the prevention of pre-programmed cell death and neuroinflammation in mild traumatic brain injury and Alzheimer's disease challenged mice

N. Greig, A. Hoffman, C. Lupica, 2019, Neurobiology of Disease.

(-)-Phenserine Ameliorates Contusion Volume, Neuroinflammation, and Behavioral Impairments Induced by Traumatic Brain Injury in Mice

N. Greig, B. Hoffer, W. Selman, 2019, Cell transplantation.

Pharmacokinetics and efficacy of PT302, a sustained-release Exenatide formulation, in a murine model of mild traumatic brain injury

N. Greig, Yazhou Li, B. Hoffer, 2019, Neurobiology of Disease.

Post-treatment with PT302, a long-acting Exendin-4 sustained release formulation, reduces dopaminergic neurodegeneration in a 6-Hydroxydopamine rat model of Parkinson’s disease

N. Greig, Yazhou Li, B. Hoffer, 2018, Scientific Reports.

(−)‐Phenserine tartrate (PhenT) as a treatment for traumatic brain injury

N. Greig, B. Hoffer, D. Kapogiannis, 2019, CNS neuroscience & therapeutics.

Author Correction: Post-treatment with PT302, a long-acting Exendin-4 sustained release formulation, reduces dopaminergic neurodegeneration in a 6-Hydroxydopamine rat model of Parkinson’s disease

N. Greig, Yazhou Li, B. Hoffer, 2018, Scientific Reports.

Novel, thalidomide-like, non-cereblon binding drug tetrafluorobornylphthalimide mitigates inflammation and brain injury

N. Greig, Dong Seok Kim, D. Tweedie, 2023, Journal of Biomedical Science.

Modulation of ERK1/MAPK3 potentiates ERK nuclear signalling, facilitates neuronal cell survival and improves memory in mouse models of neurodegenerative disorders

M. Giustetto, Jeremy Hall, K. Thomas, 2018 .

3,6′-Dithiopomalidomide Ameliorates Hippocampal Neurodegeneration, Microgliosis and Astrogliosis and Improves Cognitive Behaviors in Rats with a Moderate Traumatic Brain Injury

N. Greig, Dong Seok Kim, Y. Chiang, 2021, International journal of molecular sciences.

Thionated aminofluorophthalimides reduce classical markers of cellular inflammation in LPS-challenged RAW 264.7 cells.

N. Greig, D. Tweedie, M. Scerba, 2022, Bioorganic & medicinal chemistry letters.

Targeting neuroinflammation reduces synaptic, neuronal and cognitive loss in 5xFAD Alzheimer mice.

N. Greig, R. McDevitt, Dong Seok Kim, 2022, Alzheimer's & Dementia.

Chronic inflammation with microglia senescence at basal forebrain: impact on cholinergic deficit in Alzheimer’s brain haemodynamics

D. Tweedie, Barry J. Hoffer, D. Lecca, 2024, Brain communications.