T. Hayase

发表

Design, synthesis and antifungal activity of a novel water soluble prodrug of antifungal triazole.

M. Sakaitani, Y. Isshiki, N. Shimma, 2003, Bioorganic & medicinal chemistry letters.

Highly Enantioselective Catalytic Asymmetric Automultiplication of Chiral Pyrimidyl Alcohol.

Kenso Soai, Hiroshi Morioka, H. Morioka, 1996 .

Discovery of [5-Amino-1-(2-methyl-3H-benzimidazol-5-yl)pyrazol-4-yl]-(1H-indol-2-yl)methanone (CH5183284/Debio 1347), An Orally Available and Selective Fibroblast Growth Factor Receptor (FGFR) Inhibitor.

M. Ohmori, Hiroki Nishii, K. Morikami, 2016, Journal of medicinal chemistry.

Discovery of CH7057288 as an Orally Bioavailable, Selective, and Potent pan-TRK Inhibitor.

Hiroki Nishii, Fumio Watanabe, M. Matsushita, 2022, Journal of medicinal chemistry.

ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE FLUORINE-CONTAINING ALCOHOLS BY THE CATALYTIC ENANTIOSELECTIVE ALKYLATION OF ALDEHYDES

K. Soai, T. Shibata, T. Hayase, 1997 .

One-pot asymmetric autocatalytic reaction with remarkable amplification of enantiomeric excess

K. Soai, T. Shibata, T. Hayase, 1997 .

Enantioselective synthesis of chiral 5-carbamoyl-3-pyridyl alcohols by asymmetric autocatalytic reaction

H. Morioka, K. Soai, T. Shibata, 1996 .

Highly enantioselective synthesis of a chiral 3-quinolylalkanol by an asymmetric autocatalytic reaction

H. Morioka, K. Soai, T. Shibata, 1996 .

ASYMMETRIC AUTOCATALYTIC REACTION OF 3-QUINOLYLALKANOL WITH AMPLIFICATION OF ENANTIOMERIC EXCESS

K. Soai, T. Shibata, T. Hayase, 1996 .

Catalytic chirally self-replicating molecule. Asymmetric autocatalytic reaction of a zinc alkoxide of chiral 1-ferrocenyl-2-methylpropan-1-ol

K. Soai, T. Hayase, Kazuhisa Takai, 1995 .

Catalytic asymmetric synthesis of chiral diol, bis[2-(1-hydroxyalkyl)-phenyl]ether, an asymmetric autocatalytic reaction

K. Soai, Chieko Shimada, T. Hayase, 1994 .

Asymmetric synthesis of N-(diphenylphosphinyl)-ferrocenylamine by the enantioselective alkylation of ferrocenylimine

K. Soai, T. Shibata, T. Hayase, 1996 .

Asymmetric synthesis of pyrimidyl alkanol without adding chiral substances by the addition of diisopropylzinc to pyrimidine-5-carbaldehyde in conjunction with asymmetric autocatalysis

Kenso Soai, Hiroshi Morioka, Hikaru Imamura, 2003 .

An enantioselective Baylis–Hillman reaction catalyzed by chiral phosphines under atmospheric pressure

K. Soai, T. Shibata, T. Hayase, 1998 .

Asymmetric Synthesis of Chiral Secondary Alcohols with Isopropyl Substituents by the Catalytic Enantioselective Addition of Diisopropylzinc to Aldehydes using N,N-Dialkylnorephedrines as Chiral Catalysts

K. Soai, T. Hayase, T. Sugiyama, 1994 .

Highly Enantioselective Catalytic Asymmetric Automultiplication of Chiral Pyrimidyl Alcohol

Kenso Soai, Hiroshi Morioka, H. Morioka, 1996 .

Enantioselective synthesis of derivatives and structure-activity relationship study in the development of NA255 as a novel host-targeting anti-HCV agent.

M. Aoki, H. Sakamoto, K. Kawasaki, 2013, Bioorganic & medicinal chemistry letters.

Design and synthesis of novel macrocyclic 2-amino-6-arylpyrimidine Hsp90 inhibitors.

Atsushi Suda, Hiroshi Koyano, Naomi Ono, 2012, Bioorganic & medicinal chemistry letters.

Enantioselective Synthesis of Chiral 5-Carbamoyl-3-pyridyl Alcohols by Asymmetric Autocatalytic Reaction.

H. Morioka, K. Soai, T. Shibata, 1997 .

Asymmetric Synthesis using N, N-Dialkylnorephedrines and Pyrrolidinylmethanol Derivatives as Chiral Catalysts and Ligands

K. Soai, T. Hayase, 1995 .