W. Boeglin

J. Rundhaug, A. Pavone, S. Fischer, 2000, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Discovery of a second 15S-lipoxygenase in humans.

A. Brash, Min S. Chang, W. Boeglin, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Residual cyclooxygenase activity of aspirin‐acetylated COX‐2 forms 15R‐prostaglandins that inhibit platelet aggregation

O. Boutaud, M. Malkowski, J. Giménez‐Bastida, 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

A 12R-lipoxygenase in human skin: mechanistic evidence, molecular cloning, and expression.

R. Kim, A. Brash, W. Boeglin, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Detection and cellular localization of 12R-lipoxygenase in human tonsils.

A. Brash, C. Schneider, W. Boeglin, 2001, Archives of biochemistry and biophysics.

Interleukin-4 Induces 15-Lipoxygenase-1 Expression in Human Orbital Fibroblasts from Patients with Graves Disease

Terry J. Smith, A. Brash, S. Tsui, 2006, Journal of Biological Chemistry.

15-lipoxygenase-2 (15-LOX-2) is expressed in benign prostatic epithelium and reduced in prostate adenocarcinoma.

A. Brash, S. Kasper, S. Shappell, 1999, The American journal of pathology.

Epoxide hydrolase 3 (Ephx3) gene disruption reduces ceramide linoleate epoxide hydrolysis and impairs skin barrier function

D. Zeldin, M. Edin, F. Lih, 2020, The Journal of biological chemistry.

Epidermal Lipoxygenase Products of the Hepoxilin Pathway Selectively Activate the Nuclear Receptor PPARα

A. Brash, C. Schneider, W. Boeglin, 2007, Lipids.

Discovery of a second 15 S-lipoxygenase in humans

A. Brash, W. Boeglin, Min-Seok Chang, 1997 .

Cytochrome P450-type Hydroxylation and Epoxidation in a Tyrosine-liganded Hemoprotein, Catalase-related Allene Oxide Synthase*

A. Brash, W. Boeglin, 2012, The Journal of Biological Chemistry.

Thiol Reactivity of Curcumin and Its Oxidation Products.

P. B. Luis, C. Schneider, W. Boeglin, 2018, Chemical research in toxicology.

Site-directed mutagenesis studies on a putative fifth iron ligand of mouse 8S-lipoxygenase: retention of catalytic activity on mutation of serine-558 to asparagine, histidine, or alanine.

R. Kim, A. Brash, M. Jisaka, 2001, Archives of biochemistry and biophysics.

15S-Hydroxyeicosatetraenoic acid activates peroxisome proliferator-activated receptor gamma and inhibits proliferation in PC3 prostate carcinoma cells.

Rajnish A. Gupta, R. Matusik, T. Wheeler, 2001, Cancer research.

Detection and subcellular localization of two 15S-lipoxygenases in human cornea.

R. Roberts, A. Brash, C. Schneider, 2005, Investigative ophthalmology & visual science.

Convergence of the 5-LOX and COX-2 pathways: heme-catalyzed cleavage of the 5S-HETE-derived di-endoperoxide into aldehyde fragments

Takashi Suzuki, C. Schneider, M. Griesser, 2009, Journal of Lipid Research.

Investigation of a second 15S-lipoxygenase in humans and its expression in epithelial tissues.

R. Matusik, A. Brash, L. Nanney, 1999, Advances in experimental medicine and biology.

The hepoxilin connection in the epidermis

A. Brash, C. Schneider, W. Boeglin, 2007, The FEBS journal.

COX-2-dependent and -independent biosynthesis of dihydroxy-arachidonic acids in activated human leukocytes

Takashi Suzuki, N. Tejera, C. Schneider, 2012, Journal of Lipid Research.

Formation of epoxyalcohols by a purified allene oxide synthase. Implications for the mechanism of allene oxide synthesis.

A. Brash, T. Harris, S. Baertschi, 1993, The Journal of biological chemistry.

Monolayer autoxidation of arachidonic acid to epoxyeicosatrienoic acids as a model of their potential formation in cell membranes

M. Calcutt, A. Brash, D. Stec, 2021, Journal of lipid research.

Oxidation of C18 Hydroxy-Polyunsaturated Fatty Acids to Epoxide or Ketone by Catalase-Related Hemoproteins Activated with Iodosylbenzene

A. Brash, T. Teder, W. Boeglin, 2017, Lipids.

The lipoxygenase gene ALOXE3 implicated in skin differentiation encodes a hydroperoxide isomerase

L. Marnett, A. Brash, C. Schneider, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Elevated expression of 12/15-lipoxygenase and cyclooxygenase-2 in a transgenic mouse model of prostate carcinoma.

R. Roberts, R. Matusik, A. Brash, 2003, Cancer research.

Omega-3 fatty acids are oxygenated at the n-7 carbon by the lipoxygenase domain of a fusion protein in the cyanobacterium Acaryochloris marina.

A. Brash, W. Boeglin, B. Gao, 2010, Biochimica et biophysica acta.

A mouse mutation in the 12R-lipoxygenase, Alox12b, disrupts formation of the epidermal permeability barrier.

J. Moran, D. Beier, A. Brash, 2007, The Journal of investigative dermatology.

Human and mouse eLOX3 have distinct substrate specificities: implications for their linkage with lipoxygenases in skin.

A. Brash, C. Schneider, W. Boeglin, 2006, Archives of biochemistry and biophysics.

Mutations associated with a congenital form of ichthyosis (NCIE) inactivate the epidermal lipoxygenases 12R-LOX and eLOX3.

A. Brash, C. Schneider, W. Boeglin, 2005, Biochimica et biophysica acta.

Molecular Cloning and Functional Expression of a Phorbol Ester-inducible 8S-Lipoxygenase from Mouse Skin*

R. Kim, A. Brash, L. Nanney, 1997, The Journal of Biological Chemistry.

Allene oxide and aldehyde biosynthesis in starfish oocytes.

L. Meijer, A. Brash, M. Hughes, 1991, The Journal of biological chemistry.

Lipoxygenase-catalyzed transformation of epoxy fatty acids to hydroxy-endoperoxides: a potential P450 and lipoxygenase interaction[S]

A. Brash, T. Teder, W. Boeglin, 2014, Journal of Lipid Research.

7-HETE, 10-HETE, and 13-HETE are major products of NADPH-dependent arachidonic acid metabolism in rat liver microsomes: analysis of their stereochemistry, and the stereochemistry of their acid-catalyzed rearrangement.

A. Brash, J. Capdevila, I. Blair, 1995, Archives of biochemistry and biophysics.

Revising the structure of a new eicosanoid from human platelets to 8,9–11,12-diepoxy-13-hydroxyeicosadienoic acid

R. Murphy, A. Brash, V. O’Donnell, 2019, The Journal of Biological Chemistry.

Synthesis of dihydroperoxides of linoleic and linolenic acids and studies on their transformation to 4-hydroperoxynonenal

A. Brash, H. Yin, D. Hachey, 2005, Lipids.

Identification and absolute configuration of dihydroxy-arachidonic acids formed by oxygenation of 5S-HETE by native and aspirin-acetylated COX-2

Takashi Suzuki, S. Mulugeta, C. Schneider, 2010, Journal of Lipid Research.

Cytochrome P450-dependent transformations of 15R- and 15S-hydroperoxyeicosatetraenoic acids: stereoselective formation of epoxy alcohol products.

F. Guengerich, A. Brash, W. Boeglin, 1996, Biochemistry.

An Ancient Relative of Cyclooxygenase in Cyanobacteria Is a Linoleate 10S-Dioxygenase That Works in Tandem with a Catalase-related Protein with Specific 10S-Hydroperoxide Lyase Activity*

A. Brash, W. Boeglin, Z. Mashhadi, 2014, The Journal of Biological Chemistry.

Intermolecular peroxyl radical reactions during autoxidation of hydroxy and hydroperoxy arachidonic acids generate a novel series of epoxidized products.

A. Brash, H. Yin, N. Porter, 2008, Chemical research in toxicology.

A. Brash, H. Lõhelaid, T. Teder, 2015, The Journal of Biological Chemistry.

Isolation and Characterization of Two Geometric Allene Oxide Isomers Synthesized from 9S-Hydroperoxylinoleic Acid by Cytochrome P450 CYP74C3

A. Brash, M. Voehler, D. Stec, 2013, The Journal of Biological Chemistry.

Dehydrogenase reductase 9 (SDR9C4) and related homologs recognize a broad spectrum of lipid mediator oxylipins as substrates

K. M. Popov, A. Brash, S. Wendell, 2021, The Journal of biological chemistry.

The Structure of Human 5-Lipoxygenase

A. Brash, M. Newcomer, N. Gilbert, 2011, Science.

Functional Expression and Cellular Localization of a Mouse Epidermal Lipoxygenase*

E. Oliw, A. Brash, C. Funk, 1996, The Journal of Biological Chemistry.

8R-Lipoxygenase-catalyzed synthesis of a prominent cis-epoxyalcohol from dihomo-γ-linolenic acid: a distinctive transformation compared with S-lipoxygenases[S]

A. Brash, J. Cha, Jing Jin, 2012, Journal of Lipid Research.

Evidence for an Ionic Intermediate in the Transformation of Fatty Acid Hydroperoxide by a Catalase-related Allene Oxide Synthase from the Cyanobacterium Acaryochloris marina*

A. Brash, Yuxiang Zheng, C. Schneider, 2009, The Journal of Biological Chemistry.

The origin of 15R-prostaglandins in the Caribbean coral Plexaura homomalla: Molecular cloning and expression of a novel cyclooxygenase

A. Brash, I. Järving, N. Samel, 2001, Proceedings of the National Academy of Sciences of the United States of America.

A fungal catalase reacts selectively with the 13S fatty acid hydroperoxide products of the adjacent lipoxygenase gene and exhibits 13S-hydroperoxide-dependent peroxidase activity.

A. Brash, C. Schneider, T. Teder, 2017, Biochimica et biophysica acta. Molecular and cell biology of lipids.

The Precise Structures and Stereochemistry of Trihydroxy-linoleates Esterified in Human and Porcine Epidermis and Their Significance in Skin Barrier Function

Christopher P. Thomas, M. Calcutt, A. Brash, 2016, The Journal of Biological Chemistry.

Steric analysis of epoxyalcohol and trihydroxy derivatives of 9-hydroperoxy-linoleic acid from hematin and enzymatic synthesis.

Christopher P. Thomas, A. Brash, V. O’Donnell, 2013, Chemistry and physics of lipids.

A Critical Role of Non-active Site Residues on Cyclooxygenase Helices 5 and 6 in the Control of Prostaglandin Stereochemistry at Carbon 15*

A. Brash, I. Järving, N. Samel, 2007, Journal of Biological Chemistry.

Role of the conserved distal heme asparagine of coral allene oxide synthase (Asn137) and human catalase (Asn148): mutations affect the rate but not the essential chemistry of the enzymatic transformations.

A. Brash, W. Boeglin, B. Gao, 2008, Archives of biochemistry and biophysics.

An ensemble of lipoxygenase structures reveals novel conformations of the Fe coordination sphere

A. Brash, M. Newcomer, S. Pakhomova, 2019, Protein science : a publication of the Protein Society.

Enantiomeric separation of hydroxy eicosanoids by chiral column chromatography: effect of the alcohol modifier.

A. Brash, C. Schneider, W. Boeglin, 2000, Analytical biochemistry.

SDR9C7 catalyzes critical dehydrogenation of acylceramides for skin barrier formation.

M. Akiyama, Y. Okuno, M. Calcutt, 2020, The Journal of clinical investigation.

The 1.85 A structure of an 8R-lipoxygenase suggests a general model for lipoxygenase product specificity.

A. Brash, M. Newcomer, N. Gilbert, 2009, Biochemistry.

Lipidomic and transcriptional analysis of the linoleoyl-omega-hydroxyceramide biosynthetic pathway in human psoriatic lesions

Christopher P. Thomas, R. Murphy, J. Birchall, 2021, Journal of lipid research.

Human cyclo-oxygenase-1 and an alternative splice variant: contrasts in expression of mRNA, protein and catalytic activities.

A. Brash, C. Schneider, W. Boeglin, 2005, The Biochemical journal.

Biomimetic synthesis of hemiketal eicosanoids for biological testing.

Takashi Suzuki, J. Giménez‐Bastida, C. Schneider, 2017, Prostaglandins & other lipid mediators.

Biosynthesis of hemiketal eicosanoids by cross-over of the 5-lipoxygenase and cyclooxygenase-2 pathways

A. Pozzi, Takashi Suzuki, N. Tejera, 2011, Proceedings of the National Academy of Sciences.

Conversion of human 5‐lipoxygenase to a 15‐lipoxygenase by a point mutation to mimic phosphorylation at Serine‐663

A. Brash, M. Newcomer, Z. Rui, 2012 .

Role of the conserved distal heme asparagine in coral allene oxide synthase and human catalase

A. Brash, W. Boeglin, B. Gao, 2008 .

Inhibitory effects of a novel Val to Thr mutation on the distal heme of human catalase.

A. Brash, W. Boeglin, Z. Mashhadi, 2014, Biochimie.

Crystal Structure of a Lipoxygenase in Complex with Substrate

A. Brash, M. Newcomer, G. Bender, 2014, The Journal of Biological Chemistry.

The structure and peroxidase activity of a 33‐kDa catalase‐related protein from Mycobacterium avium ssp. paratuberculosis

A. Brash, M. Newcomer, S. Pakhomova, 2009, Protein science : a publication of the Protein Society.

Molecular cloning of a second human 15S-lipoxygenase and its murine homologue, an 8S-lipoxygenase. Their relationship to other mammalian lipoxygenases.

A. Brash, M. Jisaka, W. Boeglin, 1999, Advances in experimental medicine and biology.

OF 8 R-LIPOXYGENASE ARACHIDONIC ACID-BINDING SITE Complex with Substrate : THE Crystal Structure of a Lipoxygenase in Protein Structure and Folding :

A. Brash, M. Newcomer, G. Bender, 2014 .

Synthesis and Applications of Stereospecifically 3H-Labeled Arachidonic Acids as Mechanistic Probes for Lipoxygenase and Cyclooxygenase Catalysis1☆

A. Brash, C. Schneider, J. Cha, 2000 .

Recombinant PNPLA1 catalyzes the synthesis of acylceramides and acyl acids with selective incorporation of linoleic acid

A. Brash, Jason M. Meyer, W. Boeglin, 2023, Journal of lipid research.

Revising the structure of a new eicosanoid from human platelets to 8,9 –11,12-diepoxy-13-hydroxyeicosadienoic acid

A. Brash, V. O’Donnell, Maceler Aldrovandi, 2023 .

Analysis of cyclooxygenase-substrate interactions using stereospecifically-labeled arachidonic acids.

A. Brash, C. Schneider, W. Boeglin, 2002, Advances in experimental medicine and biology.

The Basis of Prostaglandin Synthesis in Coral

A. Brash, M. Ustav, I. Järving, 2001, The Journal of Biological Chemistry.

Convergent oxygenation of arachidonic acid by 5-lipoxygenase and cyclooxygenase-2.

H. Yin, M. Voehler, D. Stec, 2006, Journal of the American Chemical Society.

Evaluation of ω-alkynyl-labeled linoleic and arachidonic acids as substrates for recombinant lipoxygenase pathway enzymes.

M. Calcutt, A. Brash, D. Stec, 2023, Biochimica et biophysica acta. Molecular and cell biology of lipids.

COX-2-dependent and -independent biosynthesis of dihydroxy-arachidonic acids in activated human leukocytes

Takashi Suzuki, N. Tejera, C. Schneider, 2012, Journal of Lipid Research.

The 1.85 A structure of an 8R-lipoxygenase suggests a general model for lipoxygenase product specificity.

A. Brash, M. Newcomer, N. Gilbert, 2009, Biochemistry.

Robust inhibitory effects of conjugated linolenic acids on a cyclooxygenase-related linoleate 10S-dioxygenase: Comparison with COX-1 and COX-2.

A. Brash, W. Boeglin, Z. Mashhadi, 2015, Biochimica et biophysica acta.

Two C18 hydroxy-cyclohexenone fatty acids from mammalian epidermis: Potential relation to 12R-lipoxygenase and covalent binding of ceramides

M. Calcutt, A. Brash, Jason M. Meyer, 2023, The Journal of biological chemistry.

Epidermal lipoxygenase products of the hepoxilin pathway selectively activate the nuclear receptor PPARalpha.

A. Brash, W. Boeglin, Zheyong Yu, 2007, Lipids.

On the basis for the positional specificity and stereo specificity of lipoxygenases

A. Brash, C. Schneider, M. Jisaka, 2002 .

Fatty acids of Helicobacter pylori lipoproteins CagT and Lpp20

M. S. McClain, A. Brash, W. Boeglin, 2024, Microbiology spectrum.

Measurement of the Nucleon $F^n_2/F^p_2$ Structure Function Ratio by the Jefferson Lab MARATHON Tritium/Helium-3 Deep Inelastic Scattering Experiment

Stony Brook University, Nuruzzaman, Yerevan Physics Institute, 2021, 2104.05850.