H. Beggs

发表

Integrin-linked kinase deletion in the developing lens leads to capsule rupture, impaired fiber migration and non-apoptotic epithelial cell death.

S. Dedhar, J. Wolfe, L. Cammas, 2012, Investigative ophthalmology & visual science.

Hair cycle and wound healing in mice with a keratinocyte-restricted deletion of FAK

J. Jorcano, S. Fisher, K. Howerton, 2006, Oncogene.

Conditional Deletion of Focal Adhesion Kinase Leads to Defects in Ventricular Septation and Outflow Tract Alignment

R. Schwartz, L. Reichardt, O. Smithies, 2007, Molecular and Cellular Biology.

Myocyte-Restricted Focal Adhesion Kinase Deletion Attenuates Pressure Overload–Induced Hypertrophy

M. Rojas, L. Reichardt, Joan M. Taylor, 2006, Circulation research.

Focal adhesion kinase is required for synovial fibroblast invasion, but not murine inflammatory arthritis

T. Ludwig, T. Warner, A. Huttenlocher, 2014, Arthritis Research & Therapy.

Focal Adhesion Kinase Regulates the Localization and Retention of Pro-B Cells in Bone Marrow Microenvironments

J. Manis, B. Harley, Shin-Young Park, 2013, The Journal of Immunology.

NCAM140 Interacts with the Focal Adhesion Kinase p125fak and the SRC-related Tyrosine Kinase p59fyn*

P. Maness, J. Hemperly, H. Beggs, 1997, The Journal of Biological Chemistry.

Reconciling the roles of FAK in osteoblast differentiation, osteoclast remodeling, and bone regeneration.

C. Luppen, Jae‐Beom Kim, J. Helms, 2007, Bone.

Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling.

W. Gerald, F. Giancotti, L. Reichardt, 2009, The Journal of clinical investigation.

Regulation of lamellipodial persistence, adhesion turnover, and motility in macrophages by focal adhesion kinase

J. Parsons, M. Vicente-Manzanares, A. Horwitz, 2007, The Journal of cell biology.

Essential role for focal adhesion kinase in regulating stress hematopoiesis.

Baskar Ramdas, Sasidhar Vemula, R. Kapur, 2010, Blood.

Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamics

H. Pasolli, E. Fuchs, L. Reichardt, 2007, The Journal of cell biology.

Focal adhesion kinase is required for the spatial organization of the leading edge in migrating cells

J. Parsons, N. Sergina, M. Iwanicki, 2005, Journal of Cell Science.

Tumorigenesis and Neoplastic Progression Mammary Epithelial-Specific Disruption of Focal Adhesion Kinase Retards Tumor Formation and Metastasis in a Transgenic Mouse Model of Human Breast Cancer

Paolo P. Provenzano, K. Eliceiri, D. Inman, 2008 .

FAK Deficiency in Cells Contributing to the Basal Lamina Results in Cortical Abnormalities Resembling Congenital Muscular Dystrophies

K. Nave, D. Sretavan, S. Goebbels, 2003, Neuron.

Cardiac fibroblasts require focal adhesion kinase for normal proliferation and migration.

I. Thievessen, Sergey V Plotnikov, Seok‐Min Kang, 2009, American journal of physiology. Heart and circulatory physiology.

Control of axonal branching and synapse formation by focal adhesion kinase

L. Reichardt, B. Rico, Nikole E. Kimes, 2004, Nature Neuroscience.

Endothelial FAK is essential for vascular network stability, cell survival, and lamellipodial formation

R. Braren, Rong A. Wang, L. Reichardt, 2006, The Journal of cell biology.

The focal adhesion kinase inhibitor PF-562,271 impairs primary CD4+ T cell activation.

A. Huttenlocher, David A Bennin, A. Wiemer, 2013, Biochemical pharmacology.

Netrin requires focal adhesion kinase and Src family kinases for axon outgrowth and attraction

Y. Rao, Jane Y. Wu, J. Gorski, 2004, Nature Neuroscience.

A de novo X;8 translocation creates a PTK2-THOC2 gene fusion with THOC2 expression knockdown in a patient with psychomotor retardation and congenital cerebellar hypoplasia

F. Tempia, A. Durr, S. Forlani, 2013, Journal of Medical Genetics.

Cdc42- and IRSp53-dependent contractile filopodia tether presumptive lens and retina to coordinate epithelial invagination

R. Lang, G. Scita, Yi Zheng, 2009, Development.

Complete focal adhesion kinase deficiency in the mammary gland causes ductal dilation and aberrant branching morphogenesis through defects in Rho kinase‐dependent cell contractility

E. Danen, B. Water, R. Lalai, 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

PTK2b function during fertilization of the mouse oocyte.

Jinping Luo, L. McGinnis, C. Carlton, 2014, Biochemical and biophysical research communications.

Focal adhesion kinase (FAK): A regulator of CNS myelination

B. Fuss, L. Reichardt, R. Colello, 2009, Journal of neuroscience research.

Focal adhesion kinase is required for CXCL12-induced chemotactic and pro-adhesive responses in hematopoietic precursor cells

J. Lieberman, D. Dykxhoorn, R. Mulligan, 2007, Leukemia.

Regulation of lamellipodial persistence, adhesion turnover, and motility in macrophages by focal adhesion kinase

J. Parsons, M. Vicente-Manzanares, A. Horwitz, 2007, The Journal of cell biology.