F. Tang

发表

Design, synthesis, and evaluations of substituted 3-[(3- or 4-carboxyethylpyrrol-2-yl)methylidenyl]indolin-2-ones as inhibitors of VEGF, FGF, and PDGF receptor tyrosine kinases.

G. Mcmahon, L. Sun, C. Tang, 1999, Journal of medicinal chemistry.

A Widely Applicable, High-Throughput TR-FRET Assay for the Measurement of Kinase Autophosphorylation: VEGFR-2 as a Prototype

D. Moshinsky, R. Blake, Lany Ruslim, 2003, Journal of biomolecular screening.

Identification of substituted 3-[(4,5,6, 7-tetrahydro-1H-indol-2-yl)methylene]-1,3-dihydroindol-2-ones as growth factor receptor inhibitors for VEGF-R2 (Flk-1/KDR), FGF-R1, and PDGF-Rbeta tyrosine kinases.

S. Hubbard, G. Mcmahon, L. Sun, 2000, Journal of medicinal chemistry.

Synthesis and biological evaluations of 3-substituted indolin-2-ones: a novel class of tyrosine kinase inhibitors that exhibit selectivity toward particular receptor tyrosine kinases.

G. Mcmahon, L. Sun, C. Tang, 1998, Journal of medicinal chemistry.

SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors.

Cherrington, R A Blake, S. Hubbard, 2000, Cancer research.

Glycosylation of KEAP1 links nutrient sensing to redox stress signaling

J. Chi, M. B. Major, M. Boyce, 2017, The EMBO journal.

Sustained regression of tumors upon MYC inactivation requires p53 or thrombospondin-1 to reverse the angiogenic switch

E. Passegué, D. Felsher, J. Folkman, 2006, Proceedings of the National Academy of Sciences.

Genomically complex lymphomas undergo sustained tumor regression upon MYC inactivation unless they acquire novel chromosomal translocations.

D. Felsher, G. Levan, S. Giuriato, 2003, Blood.

Discovery of 5-[5-fluoro-2-oxo-1,2- dihydroindol-(3Z)-ylidenemethyl]-2,4- dimethyl-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)amide, a novel tyrosine kinase inhibitor targeting vascular endothelial and platelet-derived growth factor receptor tyrosine kinase.

Hui Chen, Chris Liang, C. Liang, 2003, Journal of medicinal chemistry.

Induces Regression of Established Tumors SU 6668 Is a Potent Antiangiogenic and Antitumor Agent That Updated

S. Hubbard, A. Ullrich, N. Shenoy, 2000 .

SU 6668 Is a Potent Antiangiogenic and Antitumor Agent That Induces Regression of Established Tumors 1

S. Hubbard, A. Ullrich, N. Shenoy, 2000 .