Amélie Hu

Oxidative stress and loss of Fe-S proteins in Friedreich ataxia induced pluripotent stem cell-derived PSNs can be reversed by restoring FXN expression with a benzamide HDAC inhibitor

M. Pandolfo, Myriam Rai, S. Donatello, 2017, bioRxiv.

Hedgehog Signaling Modulates Glial Proteostasis and Lifespan.

S. Birman, P. Thérond, Amélie Hu, 2020, Cell reports.

Friedreich ataxia-induced pluripotent stem cell-derived neurons show a cellular phenotype that is corrected by a benzamide HDAC inhibitor.

M. Pandolfo, F. Codazzi, F. Grohovaz, 2016, Human molecular genetics.

Exenatide induces frataxin expression and improves mitochondrial function in Friedreich ataxia.

M. Pandolfo, P. Marchetti, D. Eizirik, 2019, JCI insight.

Unveiling a common mechanism of apoptosis in β-cells and neurons in Friedreich's ataxia.

M. Pandolfo, P. Marchetti, D. Eizirik, 2015, Human molecular genetics.

Study of beta cells and neurons indicate incretin analogs as potential therapeutics for Friedreich’s ataxia. (S32.005)

M. Pandolfo, D. Eizirik, M. Igoillo-Esteve, 2015 .