A. Tortajada

发表

Familial C3 glomerulonephritis caused by a novel CFHR5-CFHR2 fusion gene.

C. Ghossein, Richard J. H. Smith, Xue Xiao, 2016, Molecular immunology.

C3 glomerulopathy-associated CFHR1 mutation alters FHR oligomerization and complement regulation.

S. Rodríguez de Córdoba, P. Sánchez-Corral, O. Llorca, 2013, The Journal of clinical investigation.

FHR-1 Binds to C-Reactive Protein and Enhances Rather than Inhibits Complement Activation

S. Rodríguez de Córdoba, T. Jokiranta, Z. Prohászka, 2017, The Journal of Immunology.

T. Jokiranta, Z. Prohászka, S. Lea, 2017 .

How novel structures inform understanding of complement function

O. Llorca, S. D. de Córdoba, H. Yébenes, 2017, Seminars in Immunopathology.

The role of complement in IgA nephropathy.

E. Gutiérrez, M. Pickering, N. Medjeral-Thomas, 2019, Molecular immunology.

O35Factor H allele-specific quantification in Tyr402His heterozygotes reveals the existence of low-expression alleles associated with atypical haemolytic uraemic syndrome

P. Sánchez-Corral, B. Morgan, S. R. Córdoba, 2007 .

Interaction between Multimeric von Willebrand Factor and Complement: A Fresh Look to the Pathophysiology of Microvascular Thrombosis

G. Remuzzi, M. Noris, M. Galbusera, 2017, The Journal of Immunology.

This information is current as Activation in Disease Models Proconvertase and Inhibits Complement that Blocks Formation of the C3bB A Novel Antibody against Human Factor B

M. Noris, O. Llorca, B. Morgan, 2014 .

3D structure of the C3bB complex provides insights into the activation and regulation of the complement alternative pathway convertase

O. Llorca, S. D. de Córdoba, A. Tortajada, 2009, Proceedings of the National Academy of Sciences.

The molecular and structural bases for the association of complement C3 mutations with atypical hemolytic uremic syndrome

S. Rodríguez de Córdoba, M. López-Trascasa, P. Sánchez-Corral, 2015, Molecular immunology.

Activation of the Unfolded Protein Response (UPR) Is Associated with Cholangiocellular Injury, Fibrosis and Carcinogenesis in an Experimental Model of Fibropolycystic Liver Disease

C. Trautwein, S. Rodríguez-Perales, A. Villanueva, 2021, Cancers.

A novel atypical hemolytic uremic syndrome-associated hybrid CFHR1/CFH gene encoding a fusion protein that antagonizes factor H-dependent complement regulation.

G. Remuzzi, S. Rodríguez de Córdoba, M. Noris, 2015, Journal of the American Society of Nephrology : JASN.

Complement dysregulation and disease: from genes and proteins to diagnostics and drugs.

B. Morgan, S. R. Córdoba, C. Harris, 2012, Immunobiology.

Functional basis of protection against age-related macular degeneration conferred by a common polymorphism in complement factor B

S. Rodríguez de Córdoba, B. Morgan, C. Harris, 2009, Proceedings of the National Academy of Sciences.

S. Rodríguez de Córdoba, E. Goicoechea de Jorge, M. Józsi, 2015, Trends in immunology.

Elevated factor H-related protein 1 and factor H pathogenic variants decrease complement regulation in IgA nephropathy.

S. Rodríguez de Córdoba, E. Goicoechea de Jorge, M. López-Trascasa, 2017, Kidney international.

Structural basis for the stabilization of the complement alternative pathway C3 convertase by properdin

S. Rodríguez de Córdoba, O. Llorca, M. Alcorlo, 2013, Proceedings of the National Academy of Sciences.

Coexistence of Closed and Open Conformations of Complement Factor B in the Alternative Pathway C3bB(Mg2+) Proconvertase12

S. Rodríguez de Córdoba, O. Llorca, A. Tortajada, 2009, The Journal of Immunology.

Proconvertase ) 2 + the Alternative Pathway C 3 bB ( Mg Conformations of Complement Factor B in Coexistence of Closed and Open

O. Llorca, S. R. Córdoba, A. Tortajada, 2009 .

Serum properdin consumption as a biomarker of C5 convertase dysregulation in C3 glomerulopathy

S. Rodríguez de Córdoba, M. López-Trascasa, F. Corvillo, 2016, Clinical and experimental immunology.

Factor H Competitor Generated by Gene Conversion Events Associates with Atypical Hemolytic Uremic Syndrome.

G. Remuzzi, S. Rodríguez de Córdoba, E. Goicoechea de Jorge, 2017, Journal of the American Society of Nephrology : JASN.

Complement factor H variants I890 and L1007 while commonly associated with atypical hemolytic uremic syndrome are polymorphisms with no functional significance.

M. López-Trascasa, P. Sánchez-Corral, S. D. de Córdoba, 2012, Kidney international.

Measurement of factor H variants in plasma using variant-specific monoclonal antibodies: application to assessing risk of age-related macular degeneration.

S. Rodríguez de Córdoba, B. Morgan, B. Morgan, 2008, Investigative ophthalmology & visual science.

Human C3 mutation reveals a mechanism of dense deposit disease pathogenesis and provides insights into complement activation and regulation.

S. Rodríguez de Córdoba, M. López-Trascasa, M. Heurich, 2010, The Journal of clinical investigation.

Genetics of Atypical Hemolytic Uremic Syndrome (aHUS)

S. Rodríguez de Córdoba, A. Tortajada, S. Pinto, 2014, Seminars in Thrombosis & Hemostasis.

Complete functional characterization of disease-associated genetic variants in the complement factor H gene.

S. Rodríguez de Córdoba, A. Tortajada, J. García-Fernández, 2017, Kidney international.

S. Rodríguez de Córdoba, E. Goicoechea de Jorge, P. Sánchez-Corral, 2022, Journal of the American Society of Nephrology : JASN.

The disease-protective complement factor H allotypic variant Ile62 shows increased binding affinity for C3b and enhanced cofactor activity.

B. Morgan, C. Harris, S. D. de Córdoba, 2009, Human molecular genetics.

Variant-specific quantification of factor H in plasma identifies null alleles associated with atypical hemolytic uremic syndrome.

B. Morgan, C. Harris, S. D. de Córdoba, 2010, Kidney international.

A Novel Antibody against Human Factor B that Blocks Formation of the C3bB Proconvertase and Inhibits Complement Activation in Disease Models

S. Rodríguez de Córdoba, M. Noris, O. Llorca, 2014, The Journal of Immunology.

Atypical Hemolytic Uremic Syndrome-Associated Variants and Autoantibodies Impair Binding of Factor H and Factor H-Related Protein 1 to Pentraxin 3

S. Rodríguez de Córdoba, M. López-Trascasa, P. Sánchez-Corral, 2012, The Journal of Immunology.

Molecular Basis of Factor H R1210C Association with Ocular and Renal Diseases.

S. Rodríguez de Córdoba, M. Noris, M. Blasco, 2016, Journal of the American Society of Nephrology : JASN.

Functional and structural characterization of four mouse monoclonal antibodies to complement C3 with potential therapeutic and diagnostic applications

S. Rodríguez de Córdoba, O. Llorca, M. Domínguez, 2017, European journal of immunology.

Atypical Hemolytic Uremic Syndrome-Associated Variants and Autoantibodies Impair Binding of Factor H and Factor H-Related Protein 1 to Pentraxin 3

S. Rodríguez de Córdoba, M. López-Trascasa, P. Sánchez-Corral, 2012, The Journal of Immunology.

Complement dysregulation and disease: from genes and proteins to diagnostics and drugs.

C. Harris, S. D. de Córdoba, A. Tortajada, 2012, Immunobiology.

S. Rodríguez de Córdoba, E. Goicoechea de Jorge, M. Józsi, 2015, Trends in immunology.