Marta Domínguez

发表

Structural Coupling of 11‐cis‐7‐Methyl‐retinal and Amino Acids at the Ligand Binding Pocket of Rhodopsin †

P. Garriga, R. Álvarez, M. Aguilà, 2009, Photochemistry and photobiology.

Aldo-keto reductases from the AKR1B subfamily: retinoid specificity and control of cellular retinoic acid levels.

R. Álvarez, C. Rovira, A. D. de Lera, 2009, Chemico-biological interactions.

Synthesis of C11-to-C14 methyl-shifted all-trans-retinal analogues and their activities on human aldo-keto reductases.

R. Álvarez, A. D. de Lera, J. Farrés, 2020, Organic & biomolecular chemistry.

Stereocontrolled synthesis of (S)-9-cis-4-oxo-13,14-dihydroretinoic acid

A. Lera, R. Álvarez, S. Álvarez, 2012 .

Synthesis of C40‐Symmetrical Fully Conjugated Carotenoids by Olefin Metathesis

A. Lera, R. Álvarez, Noelia Fontán, 2011 .

Total synthesis of peridinin and related C37-norcarotenoid butenolides.

R. Álvarez, A. D. de Lera, Belén Vaz, 2007, Chemistry.

Synthesis of apocarotenoids by acyclic cross metathesis and characterization as substrates for human retinaldehyde dehydrogenases

A. Lera, R. Álvarez, J. Farrés, 2018 .

Total Synthesis of Homo- and Heterodimeric Bispyrrolidinoindoline Dioxopiperazine Natural Products.

R. Álvarez, A. D. de Lera, S. Álvarez, 2021, Journal of natural products.

Synthesis of enantiopure C3- and C4-hydroxyretinals and their enzymatic reduction by ADH8 from Xenopus laevis.

R. Álvarez, A. D. de Lera, J. Farrés, 2006, Organic & biomolecular chemistry.

Improved synthesis of key fragments for the preparation of natural product incednine

José A. Souto, A. Lera, R. Álvarez, 2019, Tetrahedron.

A methyl group at C7 of 11-cis-retinal allows chromophore formation but affects rhodopsin activation

P. Garriga, A. Lera, R. Álvarez, 2006, Vision Research.

Probing a Polar Cluster in the Retinal Binding Pocket of Bacteriorhodopsin by a Chemical Design Approach

A. D. de Lera, A. Perálvarez-Marín, J. Bourdelande, 2012, PloS one.

The Role of the 11‐cis‐Retinal Ring Methyl Substituents in Visual Pigment Formation

K. Palczewski, R. Álvarez, A. D. de Lera, 2006, ChemBioChem.

The Stille reaction in the synthesis of the C37-norcarotenoid butenolide pyrrhoxanthin. Scope and limitations.

R. Álvarez, A. D. de Lera, Belén Vaz, 2006, The Journal of organic chemistry.

Specificity of zebrafish retinol saturase: formation of all-trans-13,14-dihydroretinol and all-trans-7,8- dihydroretinol.

K. Palczewski, A. D. de Lera, J. von Lintig, 2007, Biochemistry.

Aldo-keto reductases in retinoid metabolism: search for substrate specificity and inhibitor selectivity.

R. Álvarez, A. D. de Lera, J. Farrés, 2013, Chemico-biological interactions.

Kinetics of human alcohol dehydrogenase with ring-oxidized retinoids: effect of Tween 80.

R. Álvarez, A. D. de Lera, J. Farrés, 2004, Archives of biochemistry and biophysics.

Apo-14´-Carotenoic Acid Is a Novel Endogenous and Bioactive Apo-Carotenoid

A. D. de Lera, R. Rühl, G. Aydemir, 2019, Nutrients.

(9Z)- and (11Z)-8-methylretinals for artificial visual pigment studies: stereoselective synthesis, structure, and binding models.

F. Sussman, R. Álvarez, A. D. de Lera, 2003, Chemistry.

Synthesis of ring-oxidized retinoids as substrates of mouse class I alcohol dehydrogenase (ADH1).

R. Álvarez, A. D. de Lera, J. Farrés, 2004, Organic & biomolecular chemistry.

Activation of Retinoic Acid Receptors by Dihydroretinoids

Krzysztof Palczewski, Angel R de Lera, K. Palczewski, 2009, Molecular Pharmacology.

Stereospecificity of retinol saturase: absolute configuration, synthesis, and biological evaluation of dihydroretinoids.

Krzysztof Palczewski, Philip D Kiser, Angel R de Lera, 2008, Journal of the American Chemical Society.

Increased adiposity in the retinol saturase‐knockout mouse

Krzysztof Palczewski, Bernadette Erokwu, K. Palczewski, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Structural basis for the high all-trans-retinaldehyde reductase activity of the tumor marker AKR1B10

Angel R de Lera, Ignacio Fita, C. Rovira, 2007, Proceedings of the National Academy of Sciences.

Structural Determinants of the Selectivity of 3‐Benzyluracil‐1‐acetic Acids toward Human Enzymes Aldose Reductase and AKR1B10

G. Klebe, A. Mitschler, A. Podjarny, 2015, ChemMedChem.

Natural and Structure-based RXR Ligand Scaffolds and Their Functions.

A. D. de Lera, S. Álvarez, Marta Domínguez, 2017, Current Topics in Medicinal Chemistry.

Aldo-keto reductases in retinoid metabolism: search for substrate specificity and inhibitor selectivity.

R. Álvarez, A. D. de Lera, J. Farrés, 2013, Chemico-biological interactions.

The Role of the 11‐cis‐Retinal Ring Methyl Substituents in Visual Pigment Formation.

K. Palczewski, A. Lera, R. Álvarez, 2007 .