Kirsty Holden

Discovery of a Novel Metallo-β-Lactamase Inhibitor That Potentiates Meropenem Activity against Carbapenem-Resistant Enterobacteriaceae

I. Morrissey, D. Davies, S. Magnet, 2018, Antimicrobial Agents and Chemotherapy.

Oestrogen promotes healing in a bacterial LPS model of delayed cutaneous wound repair

S. Cruickshank, M. Hardman, D. Ansell, 2016, Laboratory Investigation.

Discovery of ANT3310, a Novel Broad-Spectrum Serine β-Lactamase Inhibitor of the Diazabicyclooctane Class, Which Strongly Potentiates Meropenem Activity against Carbapenem-Resistant Enterobacterales and Acinetobacter baumannii.

I. Morrissey, D. Davies, S. Mangani, 2020, Journal of medicinal chemistry.

ANT2681: SAR studies leading to the identification of a metallo-β-lactamase inhibitor with potential for clinical use in combination with meropenem for the treatment of infections caused by NDM-producing Enterobacteriaceae.

D. Davies, S. Mangani, P. Warn, 2020, ACS infectious diseases.

SCY-078 Demonstrates Significant Antifungal Activity in a Murine Model of Invasive Aspergillosis

K. Borroto-Esoda, P. Warn, Kirsty Holden, 2017, Open Forum Infectious Diseases.

Evaluating STZ-Induced Impaired Wound Healing in Rats.

M. Hardman, D. Ansell, Kirsty Holden, 2017, Journal of Investigative Dermatology.

Oestrogen promotes healing in a bacterial LPS model of delayed cutaneous wound repair

S. Cruickshank, M. Hardman, D. Ansell, 2016, Laboratory Investigation.

Meropenem-ANT3310, a unique β-lactam-β-lactamase inhibitor combination with expanded antibacterial spectrum against Gram-negative pathogens including carbapenem-resistant Acinetobacter baumannii

Simon Leiris, Kirsty Holden, J. Bousquet, 2024, Antimicrobial agents and chemotherapy.