R. Nakajima

发表

The most effective influence of 17-(3-ethoxypropyl) substituent on the binding affinity and the agonistic activity in KNT-127 derivatives, δ opioid receptor agonists.

H. Nagase, Shigeto Hirayama, H. Fujii, 2013, Bioorganic & medicinal chemistry.

Nonpeptide orexin type-2 receptor agonist ameliorates narcolepsy-cataplexy symptoms in mouse models

K. Vogt, T. Sakurai, M. Yanagisawa, 2017, Proceedings of the National Academy of Sciences.

Essential structure of orexin 1 receptor antagonist YNT-707, Part IV: The role of D-ring in 4,5-epoxymorphinan on the orexin 1 receptor antagonistic activity.

M. Yanagisawa, Y. Nagumo, Y. Irukayama-Tomobe, 2019, Bioorganic & medicinal chemistry letters.

Synthesis of new opioid derivatives with a propellane skeleton and their pharmacologies: Part 5, novel pentacyclic propellane derivatives with a 6-amide side chain.

Y. Nagumo, H. Nagase, A. Saitoh, 2015, Bioorganic & medicinal chemistry.

Synthesis of new opioid derivatives with a propellane skeleton and their pharmacologies: part 3, novel propellane derivatives with pentacyclic skeletons.

S. Hirono, H. Gouda, H. Nagase, 2012, Bioorganic & medicinal chemistry letters.

Pharmacological studies on new potent central depressants, 8-chloro-6-phenyl-4H-s-triazolo [4,3a][1,4] benzodiazepine (D-40tA) and its 1-methyl analogue (D-65MT).

Y. Take, R. Nakajima, Y. Nagawa, 1971, Japanese journal of pharmacology.

Structure-activity relationship of s-triazolo-1,4-benzodiazepines in central nervous depressant action.

R. Nakajima, Y. Nagawa, C. Hattori, 1971, Japanese journal of pharmacology.

Design and synthesis of quinolinopropellane derivatives with selective δ opioid receptor agonism.

S. Hirono, H. Gouda, H. Nagase, 2014, Bioorganic & Medicinal Chemistry Letters.

Antitrichomonal activity of δ opioid receptor antagonists, 7-benzylidenenaltrexone derivatives.

Y. Nagumo, H. Nagase, Tsuyoshi Saitoh, 2017, Bioorganic & medicinal chemistry.

Asymmetric Total Synthesis of Brasiliquinones B and C via Oxidative Cyclization of a Hydroquinone-Silyl Enol Ether Hybrid.

Takuya Kumamoto, R. Nakajima, Hiroki Miyake, 2022, The Journal of organic chemistry.

Pharmacologic characterization of a novel non-benzodiazepine selective anxiolytic, DN-2327.

R. Nakajima, G. Goto, N. Fukuda, 1989, Japanese journal of pharmacology.

Synthesis of new opioid derivatives with a propellane skeleton and their pharmacology. Part 2: Propellane derivatives with an amide side chain.

S. Hirono, H. Gouda, H. Nagase, 2012, Bioorganic & medicinal chemistry letters.

Synthesis of new opioid derivatives with a propellane skeleton and their pharmacology: part 1.

H. Nagase, H. Mochizuki, H. Fujii, 2011, Bioorganic & medicinal chemistry letters.

Essential structure of orexin 1 receptor antagonist YNT-707, part V: Structure-activity relationship study of the substituents on the 17-amino group.

M. Yanagisawa, Y. Nagumo, H. Nagase, 2019, Bioorganic & medicinal chemistry letters.

Design and synthesis of quinolinopropellane derivatives with selective δ opioid receptor agonism.

S. Hirono, H. Gouda, H. Nagase, 2014, Bioorganic & medicinal chemistry letters.

The most effective influence of 17-(3-ethoxypropyl) substituent on the binding affinity and the agonistic activity in KNT-127 derivatives, δ opioid receptor agonists.

H. Nagase, Shigeto Hirayama, H. Fujii, 2013, Bioorganic & medicinal chemistry.