Toshiaki Tanaka

发表

Rational drug design and synthesis of a selective opioid receptor antagonist on the basis of the accessory site concept.

M. Narita, H. Nagase, H. Mizoguchi, 2004, Bioorganic & medicinal chemistry letters.

Possible Pharmacotherapy of the Opioid κ Receptor Agonist for Drug Dependence

M. Narita, Tsutomu Suzuki, H. Nagase, 2004 .

Antipruritic activity of the κ-opioid receptor agonist, TRK-820

J. Kamei, H. Nagase, T. Endoh, 2002 .

Antipruritic activity of the kappa-opioid receptor agonist, TRK-820.

J. Kamei, H. Nagase, T. Endoh, 2002, European journal of pharmacology.

Discovery of (1R,2S)-2-{[(2,4-Dimethylpyrimidin-5-yl)oxy]methyl}-2-(3-fluorophenyl)-N-(5-fluoropyridin-2-yl)cyclopropanecarboxamide (E2006): A Potent and Efficacious Oral Orexin Receptor Antagonist.

C. Beuckmann, Shunsuke Ozaki, K. Sorimachi, 2015, Journal of medicinal chemistry.

Effect of repeated administration of TRK-820, a κ-opioid receptor agonist, on tolerance to its antinociceptive and sedative actions

H. Nagase, T. Endoh, Y. Togashi, 2004, Brain Research.

Effects of grapefruit juice on the pharmacokinetics of the calcium channel blockers nifedipine and nisoldipine

J. Azuma, I. Yamamoto, K. Yoshikawa, 1998 .

Inhibitory effects of TRK-820 on systemic skin scratching induced by morphine in rhesus monkeys.

H. Nagase, T. Endoh, Toshiaki Tanaka, 2004, Life sciences.

Involvement of central μ-opioid system in the scratching behavior in mice, and the suppression of it by the activation of κ-opioid system

H. Nagase, Y. Togashi, K. Nakao, 2003 .

Determination of specific activities and kinetic constants of biotinidase and lipoamidase in LEW rat and Lactobacillus casei (Shirota).

T. Ogata, Xiao‐Kang Li, H. Kimura, 2006, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Size-exclusion chromatography of biological samples which contain extremely alkaline proteins.

H. Kimura, Lei Guo, M. Hirano, 2003, Journal of biochemical and biophysical methods.

Separation of phenylthiohydantoin-amino acids by temperature-controlled reversed-phase high-performance liquid chromatography

M. Hirano, N. Katsumata, Toshiaki Tanaka, 1999 .

Determination of biotin (vitamin H) by the high-performance affinity chromatography with a trypsin-treated avidin-bound column.

T. Ogata, M. Hirano, T. Nagamine, 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Urinary Protein and Albumin Determinations by High-Performance Gel-Permeation Chromatography

A. Tanae, K. Yamauchi, C. Felice, 1995 .

High-performance liquid chromatographic assay for biotinidase activity in the human urine

T. Kohsaka, C. Felice, Toshiaki Tanaka, 1994 .

Suppression of Acute Herpetic Pain-Related Responses by the κ-Opioid Receptor Agonist (-)-17-Cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-[N-methyl-3-trans-3-(3-furyl) Acrylamido] Morphinan Hydrochloride (TRK-820) in Mice

Hiroshi Nagase, Hiroshi Nojima, Ichiro Takasaki, 2004, Journal of Pharmacology and Experimental Therapeutics.

Suppression of Acute Herpetic Pain-Related Responses by the (cid:1) -Opioid Receptor Agonist ( (cid:1) )-17-Cyclopropylmethyl-3,14 (cid:2) -dihydroxy-4,5 (cid:3) -epoxy-6 (cid:2) -[ N -methyl-3- tran s-3-(3-furyl) Acrylamido] Morphinan Hydrochloride (TRK-820) in Mice

I. Takasaki, H. Nojima, H. Nagase, 2004 .

Efficacy, safety, tolerability and population pharmacokinetics of tedizolid, a novel antibiotic, in Latino patients with acute bacterial skin and skin structure infections

S. Flanagan, P. Prokocimer, J. Passarell, 2016, The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases.

Improving Effects of Narazuke Lees on Fatty Liver of Rats Induced by High-Fat and High-Cholesterol Diets

Hiroko Tanaka, Toshiaki Tanaka, T. Nakasa, 2014 .

Pharmacokinetics and Safety of Tedizolid after Single and Multiple Intravenous/Oral Sequential Administrations in Healthy Chinese Subjects.

P. Hu, Kai Shen, Toshiaki Tanaka, 2016, Clinical therapeutics.

Drug design and synthesis of epsilon opioid receptor agonist: 17-(cyclopropylmethyl)-4,5alpha-epoxy-3,6beta-dihydroxy-6,14-endoethenomorphinan-7alpha-(N-methyl-N-phenethyl)carboxamide (TAN-821) inducing antinociception mediated by putative epsilon opioid receptor.

M. Narita, H. Nagase, H. Mizoguchi, 2004, Bioorganic & medicinal chemistry.

Possible pharmacotherapy of the opioid kappa receptor agonist for drug dependence.

M. Narita, Tsutomu Suzuki, H. Nagase, 2004, Annals of the New York Academy of Sciences.

Stepped assessment of gastric emptying of a solid using the i 3 C-octanoic acid breath test meal

S. Yoshida, Toshiaki Tanaka, Shinya Aoki, 2017 .

Involvement of central mu-opioid system in the scratching behavior in mice, and the suppression of it by the activation of kappa-opioid system.

H. Nagase, Y. Togashi, K. Nakao, 2003, European journal of pharmacology.

Remedy for itch

J. Kamei, H. Nagase, T. Endoh, 1997 .

Suppression of acute herpetic pain-related responses by the kappa-opioid receptor agonist (-)-17-cyclopropylmethyl-3,14beta-dihydroxy-4,5alpha-epoxy-beta-[n-methyl-3-trans-3-(3-furyl) acrylamido] morphinan hydrochloride (TRK-820) in mice.

Hiroshi Nagase, Hiroshi Nojima, Ichiro Takasaki, 2004, The Journal of pharmacology and experimental therapeutics.

In vitro and in vivo pharmacological characterization of the main metabolites of nalfurafine hydrochloride.

Y. Togashi, H. Mochizuki, Shinobu Momen, 2012, European journal of pharmacology.

Discovery of (1R,2S)-2-{[(2,4-Dimethylpyrimidin-5-yl)oxy]methyl}-2-(3-fluorophenyl)-N-(5-fluoropyridin-2-yl)cyclopropanecarboxamide (E2006): A Potent and Efficacious Oral Orexin Receptor Antagonist.

C. Beuckmann, Shunsuke Ozaki, K. Sorimachi, 2015, Journal of medicinal chemistry.