Bernd Gilsbach

发表

Allosteric Inhibition of Parkinson's-Linked LRRK2 by Constrained Peptides.

E. Kennedy, F. Ho, W. Versées, 2021, ACS chemical biology.

Structural model of the dimeric Parkinson’s protein LRRK2 reveals a compact architecture involving distant interdomain contacts

M. Ueffing, N. Janjić, A. Burgin, 2016, Proceedings of the National Academy of Sciences.

First model of dimeric LRRK2: the challenge of unrevealing the structure of a multidomain Parkinson's-associated protein.

Francesco Raimondi, C. Gloeckner, G. Guaitoli, 2016, Biochemical Society transactions.

Revisiting the Roco G-protein cycle.

A. Wittinghofer, F. Ho, S. Terheyden, 2015, The Biochemical journal.

Conformational heterogeneity of the Roc domains in C. tepidum Roc–COR and implications for human LRRK2 Parkinson mutations

A. Wittinghofer, F. Ho, Henderikus Pots, 2015, Bioscience reports.

Fluoride complexes of oncogenic Ras mutants to study the Ras-RasGAP interaction

Alfred Wittinghofer, Lothar Gremer, A. Wittinghofer, 2008, Biological chemistry.

Dictyostelium discoideum: A Model System to Study LRRK2-Mediated Parkinson Disease

P. V. Haastert, A. Kortholt, Bernd Gilsbach, 2012 .

Structural biology of the LRRK2 GTPase and kinase domains: implications for regulation

A. Kortholt, Bernd Gilsbach, Bernd K. Gilsbach, 2014, Front. Mol. Neurosci..

Structural Characterization of LRRK2 Inhibitors.

A. Wittinghofer, D. Alessi, M. Sattler, 2015, Journal of medicinal chemistry.

Roco kinase structures give insights into the mechanism of Parkinson disease-related leucine-rich-repeat kinase 2 mutations

I. Vetter, A. Wittinghofer, P. V. van Haastert, 2012, Proceedings of the National Academy of Sciences.

Regulation of LRRK2: insights from structural and biochemical analysis

C. Gloeckner, Bernd Gilsbach, M. Eckert, 2018, Biological chemistry.

Coordinated Ras and Rac Activity Shapes Macropinocytic Cups and Enables Phagocytosis of Geometrically Diverse Bacteria

A. Nikolaev, T. Soldati, A. Parnell, 2019, Current Biology.

Biochemical and kinetic properties of the complex Roco G-protein cycle

A. Wittinghofer, W. Versées, C. Gloeckner, 2018, Biological chemistry.

C2GAP2 is a common regulator of Ras signaling for chemotaxis, phagocytosis, and macropinocytosis

T. Jin, Douwe M Veltman, Henderikus Pots, 2022, Frontiers in Immunology.