M. Kaufmann

发表

Analysis of Vitamins D, Their Metabolites and Analogues

Glenville Jones, H. Makin, M. Calverley, 2010 .

Insights into Vitamin D metabolism using cyp24 over-expression and knockout systems in conjunction with liquid chromatography/mass spectrometry (LC/MS)

Glenville Jones, R. St-Arnaud, M. Gao, 2004, The Journal of Steroid Biochemistry and Molecular Biology.

Hepatic activation and inactivation of clinically-relevant vitamin D analogs and prodrugs.

R. Mehta, Glenville Jones, S. Strugnell, 2006, Anticancer research.

Update on pharmacologically-relevant vitamin D analogues.

Glenville Jones, M. Kaufmann, 2018, British journal of clinical pharmacology.

Effect of increasing doses of vitamin D on bone mineral density and serum N‐terminal telopeptide in elderly women: a randomized controlled trial

J. Gallagher, G. Jones, L. M. Smith, 2018, Journal of internal medicine.

Significance of serum 24,25-dihydroxyvitamin D in the assessment of vitamin D status: a double-edged sword?

C. Sempos, A. Hoofnagle, K. Cashman, 2015, Clinical chemistry.

Targeted genomic deletions identify diverse enhancer functions and generate a kidney-specific, endocrine-deficient Cyp27b1 pseudo-null mouse

R. Redfield, Glenville Jones, J. Pike, 2019, The Journal of Biological Chemistry.

A kidney-specific genetic control module in mice governs endocrine regulation of the cytochrome P450 gene Cyp27b1 essential for vitamin D3 activation

Glenville Jones, J. Pike, M. Meyer, 2017, The Journal of Biological Chemistry.

Navigated tissue characterization during skin cancer surgery

Tamas Ungi, Parvin Mousavi, John F. Rudan, 2020, International Journal of Computer Assisted Radiology and Surgery.

Diagnostic Aspects of Vitamin D: Clinical Utility of Vitamin D Metabolite Profiling

Glenville Jones, M. Kaufmann, 2021, JBMR plus.

PTH suppression by calcitriol does not predict off‐target actions in experimental CKD

M. Petkovich, Glenville Jones, M. Adams, 2020, Pharmacology research & perspectives.

Overlapping Phenotypes Associated With CYP24A1, SLC34A1, and SLC34A3 Mutations: A Cohort Study of Patients With Hypersensitivity to Vitamin D

J. Bacchetta, S. Lemoine, Glenville Jones, 2021, Frontiers in Endocrinology.

Vitamin D metabolite profiling using liquid chromatography–tandem mass spectrometry (LC–MS/MS)

Martin Kaufmann, Glenville Jones, Glenville Jones, 2016, The Journal of Steroid Biochemistry and Molecular Biology.

Data for the measurement of serum vitamin D metabolites in childhood acute lymphoblastic leukemia survivors

E. Levy, E. Delvin, Y. Théorêt, 2018, Data in brief.

Mass Spectrometry Assays of Vitamin D Metabolites

Ravinder J. Singh, L. Sepiashvili, M. Kaufmann, 2017 .

Clinical utility of simultaneous quantitation of 25-hydroxyvitamin D and 24,25-dihydroxyvitamin D by LC-MS/MS involving derivatization with DMEQ-TAD.

H. DeLuca, D. Cooper, J. Gallagher, 2014, The Journal of clinical endocrinology and metabolism.

Single A326G mutation converts human CYP24A1 from 25-OH-D3-24-hydroxylase into -23-hydroxylase, generating 1α,25-(OH)2D3-26,23-lactone

Glenville Jones, B. O’Leary, M. Kaufmann, 2007, Proceedings of the National Academy of Sciences.

CYP2R1 is a major, but not exclusive, contributor to 25-hydroxyvitamin D production in vivo

H. DeLuca, Glenville Jones, M. Kaufmann, 2013, Proceedings of the National Academy of Sciences.

Reliable identification of prostate cancer using mass spectrometry metabolomic imaging in needle core biopsies

R. J. Gooding, R. Oleschuk, D. Berman, 2019, Laboratory Investigation.

Mutations in CYP24A1 and idiopathic infantile hypercalcemia.

M. Konrad, H. Fehrenbach, J. Hoenderop, 2011, The New England journal of medicine.

CYP24A1 and SLC34A1 Pathogenic Variants Are Uncommon in a Canadian Cohort of Children with Hypercalcemia or Hypercalciuria

M. Pinsk, Glenville Jones, D. Pacaud, 2021, Hormone Research in Paediatrics.

Differential diagnosis of vitamin D–related hypercalcemia using serum vitamin D metabolite profiling

J. Gallagher, M. Uesugi, M. Konrad, 2021, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Vitamin D supplementation in pregnancy: A word of caution. Familial hypercalcaemia due to disordered vitamin D metabolism

Glenville Jones, S. Soule, C. Florkowski, 2020 .

Do the heterozygous carriers of a CYP24A1 mutation display a different biochemical phenotype than wild types?

C. Marcocci, F. Cetani, F. Baldinotti, 2020, The Journal of clinical endocrinology and metabolism.

Improved Screening Test for Idiopathic Infantile Hypercalcemia Confirms Residual Levels of Serum 24,25‐(OH)2D3 in Affected Patients

D. Cooper, J. Gallagher, Glenville Jones, 2017, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Calcium pyrophosphate deposition disease revealing a hypersensitivity to vitamin D.

Glenville Jones, C. Marcelli, M. Kottler, 2017, Joint, bone, spine : revue du rhumatisme.

Vitamin D metabolism in the premature newborn: A randomized trial.

E. Lyden, Glenville Jones, L. Armas, 2016, Clinical nutrition.

Dynamics of Vitamin D Metabolism in Maternal–Fetal Dyads

E. Lyden, Glenville Jones, C. Hanson, 2016, Journal of pediatric gastroenterology and nutrition.

Maternal Hypercalcemia Due to Failure of 1,25-Dihydroxyvitamin-D3 Catabolism in a Patient With CYP24A1 Mutations.

R. Nussbaum, E. Hsiao, S. Baumgartner-Parzer, 2015, The Journal of clinical endocrinology and metabolism.

Generation of a homology model for the human cytochrome P450, CYP24A1, and the testing of putative substrate binding residues by site-directed mutagenesis and enzyme activity studies.

Glenville Jones, S. Masuda, M. Kaufmann, 2007, Archives of biochemistry and biophysics.

25-Hydroxyvitamin D assays: Potential interference from other circulating vitamin D metabolites

C. Sempos, G. Jones, G. Carter, 2016, The Journal of Steroid Biochemistry and Molecular Biology.

Mineral Homeostasis in Murine Fetuses Is Sensitive to Maternal Calcitriol but Not to Absence of Fetal Calcitriol

Glenville Jones, R. St-Arnaud, M. Kaufmann, 2019, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Combined Mass Spectrometry and Histopathology Imaging for Perioperative Tissue Assessment in Cancer Surgery

Amoon Jamzad, Gabor Fichtinger, Parvin Mousavi, 2021, J. Imaging.

Improved Resection Margins in Surgical Oncology Using Intraoperative Mass Spectrometry

Parvin Mousavi, Gabor Fichtinger, Alireza Sedghi, 2020, MICCAI.

7α-Hydroxylation of dehydroepiandrosterone does not interfere with the activation of glucocorticoids by 11β-hydroxysteroid dehydrogenase in EtC cerebellar neurons

B. McEwen, K. Bulloch, A. Gottfried-Blackmore, 2013, The Journal of Steroid Biochemistry and Molecular Biology.

Maternal Vitamin D Status and Gestational Weight Gain as Correlates of Neonatal Bone Mass in Healthy Term Breastfed Young Infants from Montreal, Canada

F. Rauch, H. Weiler, Glenville Jones, 2021, Nutrients.

Oxidation of Vinyl Carbamate and Formation of 1,N6-Ethenodeoxyadenosine in Murine Lung

Glenville Jones, Ashish Sharma, K. Collins, 2007, Drug Metabolism and Disposition.

Randomized trial of two doses of vitamin D3 in preterm infants <32 weeks: Dose impact on achieving desired serum 25(OH)D3 in a NICU population

E. Lyden, Glenville Jones, C. Hanson, 2017, PloS one.

High-Dose Intramuscular Vitamin D Provides Long-Lasting Moderate Increases in Serum 25-Hydroxvitamin D Levels and Shorter-Term Changes in Plasma Calcium.

R. Lucas, M. Clarke, E. Lim, 2017, Journal of AOAC International.

The metabolism of 1,25(OH)2D3 in clinical and experimental kidney disease

M. Petkovich, Glenville Jones, P. Norman, 2022, Scientific Reports.

Vitamin D status and functional health outcomes in children aged 2-8 y: a 6-mo vitamin D randomized controlled trial.

F. Rauch, H. Weiler, Glenville Jones, 2018, The American journal of clinical nutrition.

Vitamin D–Dependent Rickets Type 1B (25‐Hydroxylase Deficiency): A Rare Condition or a Misdiagnosed Condition?

Glenville Jones, G. Weryha, P. Journeau, 2017, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Vitamin D and Diseases of Mineral Homeostasis: A Cyp24a1 R396W Humanized Preclinical Model of Infantile Hypercalcemia Type 1

Glenville Jones, R. St-Arnaud, A. Arabian, 2022, Nutrients.

A High-Calcium and Phosphate Rescue Diet and VDR-Expressing Transgenes Normalize Serum Vitamin D Metabolite Profiles and Renal Cyp27b1 and Cyp24a1 Expression in VDR Null Mice.

Glenville Jones, J. Pike, S. Lee, 2015, Endocrinology.

The 1,24,25(OH)3D3 metabolite in clinical and experimental CKD: Impact of calcitriol treatment

M. Petkovich, Glenville Jones, P. Norman, 2022, The Journal of Steroid Biochemistry and Molecular Biology.

Calcioic acid: In vivo detection and quantification of the terminal C24-oxidation product of 25-hydroxyvitamin D3 and related intermediates in serum of mice treated with 24,25-dihydroxyvitamin D3

Glenville Jones, R. St-Arnaud, A. Arabian, 2019, The Journal of Steroid Biochemistry and Molecular Biology.

Serum 24,25-dihydroxyvitamin D3 response to native vitamin D2 and D3 Supplementation in patients with chronic kidney disease on hemodialysis.

E. Lyden, Glenville Jones, M. Kaufmann, 2017, Clinical nutrition.

Preclinical safety and efficacy of 24R,25-dihydroxyvitamin D3 or lactosylceramide treatment to enhance fracture repair

Glenville Jones, R. St-Arnaud, A. Arabian, 2020, Journal of orthopaedic translation.

Interlaboratory Comparison for the Determination of 24,25-Dihydroxyvitamin D₃ in Human Serum Using Liquid Chromatography with Tandem Mass Spectrometry.

Johanna E. Camara, C. Sempos, A. Hoofnagle, 2017, Journal of AOAC International.

Two French Families with Vitamin D Dependency Rickets Type 1B Harbor Homozygous Recessive Expression Of CYP2R1 Mutations L99P and G42_L46DEL INSR

S. Brennan, Glenville Jones, F. Feillet, 2016 .

Hypercalcemia due to CYP24A1 mutations: a systematic descriptive review.

C. Marcocci, F. Cetani, F. Baldinotti, 2021, European journal of endocrinology.

Selective conversion by microglia of dehydroepiandrosterone to 5-androstenediol—A steroid with inherent estrogenic properties

B. McEwen, K. Bulloch, Glenville Jones, 2007, The Journal of Steroid Biochemistry and Molecular Biology.

Dehydroepiandrosterone (DHEA) metabolism in the brain: Identification by liquid chromatography/mass spectrometry of the delta-4-isomer of DHEA and related steroids formed from androstenedione by mouse BV2 microglia

B. McEwen, K. Bulloch, Gist Croft, 2006, The Journal of Steroid Biochemistry and Molecular Biology.

Temporal hemodynamic effects of permissive hypercapnia associated with ideal PEEP in ARDS.

M. Amato, C. Barbas, R. Kairalla, 1997, American journal of respiratory and critical care medicine.

Hereditary Hypercalcemia Caused by a Homozygous Pathogenic Variant in the CYP24A1 Gene: A Case Report and Review of the Literature

C. Marcocci, F. Cetani, E. Vignali, 2019, Case reports in endocrinology.

25-Hydroxyvitamin D-24-hydroxylase (CYP24A1): its important role in the degradation of vitamin D.

Glenville Jones, M. Kaufmann, D. Prosser, 2012, Archives of biochemistry and biophysics.

Bioengineering Anabolic Vitamin D-25-Hydroxylase Activity into the Human Vitamin D Catabolic Enzyme, Cytochrome P450 CYP24A1, by a V391L Mutation*

Glenville Jones, M. Kaufmann, D. Prosser, 2011, The Journal of Biological Chemistry.

Cytochrome P450-mediated metabolism of vitamin D

Glenville Jones, M. Kaufmann, D. Prosser, 2014, Journal of Lipid Research.

Metabolomics patterns of breast cancer tumors using mass spectrometry imaging

Randy E. Ellis, Kevin Yi Mi Ren, Sonal Varma, 2021, International Journal of Computer Assisted Radiology and Surgery.

Optimal bone fracture repair requires 24R,25-dihydroxyvitamin D3 and its effector molecule FAM57B2

Glenville Jones, R. St-Arnaud, Abdallah Husseini, 2018, The Journal of clinical investigation.

Autosomal-Recessive Mutations in SLC34A1 Encoding Sodium-Phosphate Cotransporter 2A Cause Idiopathic Infantile Hypercalcemia.

M. Konrad, E. Levtchenko, C. Wagner, 2016, Journal of the American Society of Nephrology : JASN.

Determination of Free 25(OH)D Concentrations and Their Relationships to Total 25(OH)D in Multiple Clinical Populations

R. Eastell, R. Jorde, M. Holick, 2018, The Journal of clinical endocrinology and metabolism.

Self-Supervised Learning For Detection Of Breast Cancer In Surgical Margins With Limited Data

Amoon Jamzad, Gabor Fichtinger, Parvin Mousavi, 2021, 2021 IEEE 18th International Symposium on Biomedical Imaging (ISBI).

Perioperative margin detection in basal cell carcinoma using a deep learning framework: a feasibility study

Parvin Mousavi, John F. Rudan, Gabor Fichtinger, 2020, International Journal of Computer Assisted Radiology and Surgery.

Classification of tumor signatures from electrosurgical vapors using mass spectrometry and machine learning: a feasibility study

Laura Connolly, Amoon Jamzad, Mark Asselin, 2020, Medical Imaging: Image-Guided Procedures.

Navigated real-time molecular analysis in the operating theatre: demonstration of concept

Mark Asselin, Andras Lasso, Gabor Fichtinger, 2019, Medical Imaging.

Calcitriol Accelerates Vascular Calcification Irrespective of Vitamin K Status in a Rat Model of Chronic Kidney Disease with Hyperphosphatemia and Secondary Hyperparathyroidism

Glenville Jones, M. Adams, R. Holden, 2018, The Journal of Pharmacology and Experimental Therapeutics.

Maternal outcomes and risk factors for COVID-19 severity among pregnant women

F. Malone, Y. Ville, M. Boulvain, 2021, Scientific Reports.

Effect of Vitamin D Supplementation on Bone Mass in Infants With 25-Hydroxyvitamin D Concentrations Less Than 50 nmol/L

F. Rauch, H. Weiler, O. Sotunde, 2023, JAMA pediatrics.

A chromatin-based mechanism controls differential regulation of the cytochrome P450 gene Cyp24a1 in renal and non-renal tissues

Glenville Jones, J. Pike, M. Meyer, 2019, The Journal of Biological Chemistry.

Domain adaptation and self-supervised learning for surgical margin detection

Amoon Jamzad, Gabor Fichtinger, Parvin Mousavi, 2021, International Journal of Computer Assisted Radiology and Surgery.

Importance of cytochrome P450-mediated metabolism in the mechanism of action of vitamin D analogs.

Glenville Jones, M. Gao, S. Masuda, 2003, Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer.

Inhibit progression of coronary artery calcification with vitamin k in hemodialysis patients (the iPACK-HD study): a randomized, placebo-controlled multi-centre, pilot trial.

Xueyan Fu, S. Booth, D. Heyland, 2022, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Vitamin D status in mothers with pre-eclampsia and their infants: a case–control study from Serbia, a country without a vitamin D fortification policy

M. Glibetić, H. Weiler, Glenville Jones, 2016, Public Health Nutrition.

Long-term efficacy and safety of rifampin in the treatment of a patient carrying a CYP24A1 loss-of-function variant.

C. Marcocci, F. Cetani, F. Baldinotti, 2022, The Journal of clinical endocrinology and metabolism.

Validation of a routine two‐sample iohexol plasma clearance assessment of GFR and an evaluation of common endogenous markers in a rat model of CKD

Glenville Jones, M. Turner, M. Adams, 2017, Physiological reports.

Vitamin D status in mothers with pre-eclampsia and their infants: a case–control study from Serbia, a country without a vitamin D fortification policy

M. Glibetić, H. Weiler, Glenville Jones, 2016, Public Health Nutrition.

Bioengineering Anabolic Vitamin D-25-Hydroxylase Activity into the Human Vitamin D Catabolic Enzyme, Cytochrome P450 CYP24A1, by a V391L Mutation*

Glenville Jones, M. Kaufmann, D. Prosser, 2011, The Journal of Biological Chemistry.

Measurements of the Vitamin D Metabolome in the Calgary Vitamin D Study: Relationship of Vitamin D Metabolites to Bone Loss

Glenville Jones, S. Boyd, D. Hanley, 2023, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Significance of serum 24,25-dihydroxyvitamin D in the assessment of vitamin D status: a double-edged sword?

C. Sempos, A. Hoofnagle, K. Cashman, 2015, Clinical chemistry.

Vitamin D–Dependent Rickets Type 1B (25‐Hydroxylase Deficiency): A Rare Condition or a Misdiagnosed Condition?

Glenville Jones, G. Weryha, P. Journeau, 2017, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

A phase II dose evaluation pilot feasibility randomized controlled trial of cholecalciferol in critically ill children with vitamin D deficiency (VITdAL-PICU study)

M. Lawson, K. Menon, D. Fergusson, 2023, BMC Pediatrics.

Serum 24,25-dihydroxyvitamin D3 response to native vitamin D2 and D3 Supplementation in patients with chronic kidney disease on hemodialysis.

E. Lyden, Glenville Jones, M. Kaufmann, 2017, Clinical nutrition.

Vitamin D status and functional health outcomes in children aged 2-8 y: a 6-mo vitamin D randomized controlled trial.

F. Rauch, H. Weiler, Glenville Jones, 2018, The American journal of clinical nutrition.

Epimeric vitamin D and cardiovascular structure and function in advanced CKD and after kidney transplantation.

T. Hiemstra, Kenneth Lim, T. Lu, 2023, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Loss of maternal calcitriol reversibly alters early offspring growth and skeletal development in mice

E. C. Walker, M. Kaufmann, B. J. Kirby, 2024, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Vitamin D Metabolites in Mother–Infant Dyads and Associated Clinical Outcomes in a Population of Nigerian Women

C. Hanson, A. Anderson-Berry, M. Kaufmann, 2024, Nutrients.

Maternal Hypercalcemia Due to Failure of 1,25-Dihydroxyvitamin-D3 Catabolism in a Patient With CYP24A1 Mutations.

R. Nussbaum, E. Hsiao, S. Baumgartner-Parzer, 2015, The Journal of clinical endocrinology and metabolism.

A kidney-specific genetic control module in mice governs endocrine regulation of the cytochrome P450 gene Cyp27b1 essential for vitamin D3 activation

Glenville Jones, M. Meyer, M. Onal, 2017, The Journal of Biological Chemistry.