A. Thalén

发表

Correlation between chemical structure, receptor binding, and biological activity of some novel, highly active, 16 alpha, 17 alpha-acetal-substituted glucocorticoids.

J. Gustafsson, R. Brattsand, T. Saartok, 1984, Molecular pharmacology.

Metabolic acetal splitting of budesonide. A novel inactivation pathway for topical glucocorticoids.

A. Ryrfeldt, P. Andersson, S. Edsbäcker, 1987, Drug metabolism and disposition: the biological fate of chemicals.

Influence of 16α,17α-acetal substitution and steroid nucleus fluorination on the topical to systemic activity ratio of glucocorticoids

R. Brattsand, A. Thalén, K. Roempke, 1982 .

Development of new glucocorticosteroids with a very high ratio between topical and systemic activities.

R. Brattsand, A. Thalén, K. Roempke, 1982, European journal of respiratory diseases. Supplement.

Synthesis and anti-inflammatory properties of budesonide, a new non-halogenated glucocorticoid with high local activity.

R. Brattsand, A. Thalén, 1980, Arzneimittel-Forschung.

Liver metabolism of budesonide in rat, mouse, and man. Comparative aspects.

A. Ryrfeldt, J. Paulson, P. Andersson, 1987, Drug metabolism and disposition: the biological fate of chemicals.

High-performance liquid chromatographic determination of epimers, impurities, and content of the glucocorticoid budesonide and preparation of primary standard.

L. Nilsson, A. Wikby, A. Thalén, 1980, Journal of pharmaceutical sciences.

Metabolic pathways of the topical glucocorticoid budesonide in man.

A. Ryrfeldt, S. Edsbäcker, A. Thalén, 1983, Drug metabolism and disposition: the biological fate of chemicals.

Synthesis and structure elucidation of potential 6-oxygenated metabolites of (22R)-6α,9α-difluoro-11β,21-dihydroxy-16α,17α-propylmethylenedioxypregn-4-ene-3,20-dione, and related glucocorticosteroids

A. Thalén, L. Wickström, 2000, Steroids.

Synthesis and structure elucidation of 6α- and 6β-hydroxylated budesonide and related corticosteroids

A. Thalén, LM Wickstrom, 1984 .

Synthesis and pharmacological properties of some 16 alpha,17 alpha-acetals of 16 alpha-hydroxyhydrocortisone, 16 alpha-hydroxyprednisolone and fluorinated 16 alpha-hydroxyprednisolones.

R. Brattsand, A. Thalén, E. Gruvstad, 1984, Acta pharmaceutica Suecica.

A sensitive radioimmunoassay for budesonide in plasma.

G. Aherne, V. Marks, P. Littleton, 1982, Journal of steroid biochemistry.

Influence of 16 alpha, 17 alpha-acetal substitution and steroid nucleus fluorination on the topical to systemic activity ratio of glucocorticoids.

R. Brattsand, A. Thalén, K. Roempke, 1982, Journal of steroid biochemistry.

Synthesis and crystal structure of (22R)-6α, 9α-difiuoro-11β-hydroxy21-palmitoyloxy-16α, 17α-propylmethylenedioxypreg n-4-ene-3,20-dione (rofleponide 21-palmitate)

I. Csöregh, A. Thalén, L. Wickström, 1999 .

Crystal structure of (22R)-6α,9α-difluoro-11β,21-dihydroxy-16α,17α-propylmethylenedioxypregn-4-ene-3,20-dione · 2-propanol (4:1) solvate, C25H34O6F2 · 1/4(C3H8O)

I. Csöregh, A. Thalén, L. Wickström, 1998 .

Development of glucocorticosteroids with enhanced ratio between topical and systemic effects.

P. Andersson, R. Brattsand, A. Thalén, 1989, Acta dermato-venereologica. Supplementum.

The Preparation of 3,3,5,5-Tetramethyl-1,2-dithiolane-4-one.

P. C. Kvande, E. Meisingseth, A. Thalén, 1963 .