K. Müller

发表

Depsides as non-redox inhibitors of leukotriene B4 biosynthesis and HaCaT cell growth. 1. Novel analogues of barbatic and diffractaic acid

S. Kc, K. Müller, 1999 .

Inhibitory effect of phenothiazine- and phenoxazine-derived chloroacetamides on Leishmania major growth and Trypanosoma brucei trypanothione reductase.

R. Krauth-Siegel, A. Marcu, H. Moll, 2016, European journal of medicinal chemistry.

9-Benzylidene-naphtho[2,3-b]thiophen-4-ones and benzylidene-9(10H)-anthracenones as novel tubulin interacting agents with high apoptosis-inducing activity.

A. Zuse, M. Los, J. Prehn, 2007, European journal of pharmacology.

Synthesis, Anti-Proliferative Activity Evaluation and 3D-QSAR Study of Naphthoquinone Derivatives as Potential Anti-Colorectal Cancer Agents

J. Lopez, R. Vivas-Reyes, F. Aristizábal, 2018, Molecules.

The Antipsoriatic Mahonia aquifolium and its Active Constituents; I. Pro- and Antioxidant Properties and Inhibition of 5-Lipoxygenase

K. Müller, K. Ziereis, 1994, Planta medica.

Synthesis, antiproliferative activity and inhibition of tubulin polymerization by 1,5- and 1,8-disubstituted 10H-anthracen-9-ones bearing a 10-benzylidene or 10-(2-oxo-2-phenylethylidene) moiety.

S. Baasner, M. Gerlach, P. Schmidt, 2010, European journal of medicinal chemistry.

8-Halo-substituted naphtho[2,3-b]thiophene-4,9-diones as redox-active inhibitors of keratinocyte hyperproliferation with reduced membrane-damaging properties.

H. Prinz, K. Müller, Cathrin Lindenschmidt, 2016, European journal of medicinal chemistry.

Synthesis and structure-activity relationships of lapacho analogues. 2. Modification of the basic naphtho[2,3-b]furan-4,9-dione, redox activation, and suppression of human keratinocyte hyperproliferation by 8-hydroxynaphtho[2,3-b]thiophene-4,9-diones.

H. Prinz, K. Müller, Sven Bannwitz, 2014, Journal of medicinal chemistry.

Synthesis and structure-activity relationships of lapacho analogues. 1. Suppression of human keratinocyte hyperproliferation by 2-substituted naphtho[2,3-b]furan-4,9-diones, activation by enzymatic one- and two-electron reduction, and intracellular generation of superoxide.

H. Prinz, K. Müller, Sven Bannwitz, 2012, Journal of medicinal chemistry.

Structure-activity relationship studies of acridones as potential antipsoriatic agents. 2. Synthesis and antiproliferative activity of 10-substituted hydroxy-10H-acridin-9-ones against human keratinocyte growth.

H. Prinz, K. Müller, Aleksandar Putic, 2010, European journal of medicinal chemistry.

A 1H NMR study of the interactions and conformations of rationally designed brodimoprim analogues in complexes with Lactobacillus casei dihydrofolate reductase.

J. Feeney, G. Roberts, B. Birdsall, 1984, Journal of medicinal chemistry.

Hydroxyl radical formation by dithranol.

H. Kappus, K. Müller, 1988, Biochemical pharmacology.

5‐Lipoxygenase and 12‐Lipoxygenase: Attractive Targets for the Development of Novel Antipsoriatic Drugs. 5‐Lipoxygenase und 12‐Lipoxygenase: Attraktive Target‐Enzyme für die Entwicklung neuer Antipsoriatika

K. Müller, 1994 .

Antipsoriatic and proinflammatory action of anthralin. Implications for the role of oxygen radicals.

K. Müller, 1997, Biochemical pharmacology.

Inactivation of mouse epidermal 12-lipoxygenase by anthralin--implications for the role of oxygen radicals.

K. Müller, K. Müller, I. Gawlik, 1996, Biochemical pharmacology.

Effects of reactive oxygen species on the biosynthesis of 12 (S)-hydroxyeicosatetraenoic acid in mouse epidermal homogenate.

K. Müller, I. Gawlik, 1997, Free radical biology & medicine.

Active Oxygen Species and Structure Specificity of Antipsoriatic Anthrones

K. Müller, 1988, Archiv der Pharmazie.

Formation of Active Oxygen Species by Dithranol, III Dithranol, Active Oxygen Species and Lipid Peroxidation in vivo

W. Wiegrebe, M. Younes, K. Müller, 1987, Archiv der Pharmazie.

Antipsoriatic anthrones: aspects of oxygen radical formation, challenges and prospects.

K. Müller, 1996, General pharmacology.

Hydroxyl radical damage to DNA sugar and model membranes induced by anthralin (dithranol).

K. Müller, D. Gürster, 1993, Biochemical pharmacology.

Modification of DNA bases by anthralin and related compounds.

P. Leukel, W. Wiegrebe, K. Müller, 1995, Biochemical pharmacology.

Napabucasin and Related Heterocycle-Fused Naphthoquinones as STAT3 Inhibitors with Antiproliferative Activity against Cancer Cells.

K. Müller, H. Löcken, Cinzia Clamor, 2018, Journal of natural products.

Phenylimino-10H-anthracen-9-ones as novel antimicrotubule agents-synthesis, antiproliferative activity and inhibition of tubulin polymerization.

S. Baasner, M. Gerlach, P. Schmidt, 2011, Bioorganic & medicinal chemistry.

Synthesis, antiproliferative activity and inhibition of tubulin polymerization by anthracenone-based oxime derivatives.

K. Böhm, H. Prinz, K. Müller, 2010, European journal of medicinal chemistry.

Design and synthesis of potent and highly selective thrombin inhibitors.

K Gubernator, D W Banner, D. Banner, 1994, Journal of medicinal chemistry.

10-Aminomethylene-1,8-dihydroxy-9(10H)-anthracenones: Inhibitory action against 5-lipoxygenase and the growth of HaCaT cells

A. Sellmer, H. Prinz, K. Müller, 1997 .

5-Lipoxygenase and 12-lipoxygenase: attractive targets for the development of novel antipsoriatic drugs.

K. Müller, 1994, Archiv der Pharmazie.

Oxadiazole-substituted naphtho[2,3-b]thiophene-4,9-diones as potent inhibitors of keratinocyte hyperproliferation. Structure-activity relationships of the tricyclic quinone skeleton and the oxadiazole substituent.

R. Fröhlich, H. Prinz, K. Müller, 2017, European journal of medicinal chemistry.

Potential antipsoriatic agents: lapacho compounds as potent inhibitors of HaCaT cell growth.

A. Sellmer, W. Wiegrebe, K. Müller, 1999, Journal of natural products.

N-Heterocyclic (4-Phenylpiperazin-1-yl)methanones Derived from Phenoxazine and Phenothiazine as Highly Potent Inhibitors of Tubulin Polymerization.

Jahan B. Ghasemi, E. Aghaee, K. Böhm, 2017, Journal of medicinal chemistry.

Antipsoriatic anthrones with modulated redox properties. 4. Synthesis and biological activity of novel 9,10-dihydro-1,8-dihydroxy-9-oxo-2-anthracenecarboxylic and -hydroxamic acids.

H. Prinz, K. Müller, 1997, Journal of medicinal chemistry.

Syntheses of Anthracenones. 1. Sodium Dithionite Reduction of peri-Substituted Anthracenediones.

W. Wiegrebe, H. Prinz, K. Müller, 1996, The Journal of organic chemistry.

Syntheses of Anthracenones. 2. Preparation of 1,8-Dimethoxy- (Dimethylanthralin) and 4,5-Dihydroxy-9(10H)-anthracenone (Isoanthralin): A Revision.

W. Wiegrebe, H. Prinz, T. Burgemeister, 1996, The Journal of organic chemistry.

1,4‐Dihydro‐1,4‐diazocine; N‐Substitution and Structure (“Aromaticity”)

H. Prinzbach, H. Fritz, J. Daly, 1979 .

-Oxa,aza-σ-homobenzenes

H. Prinzbach, D. Hunkler, K. Müller, 1980 .

2‐Anthracenonyl Acetic Acids as 5‐Lipoxygenase Inhibitors

H. Prinz, K. Müller, 1996, Archiv der Pharmazie.

Sulfonate derivatives of naphtho[2,3-b]thiophen-4(9H)-one and 9(10H)-anthracenone as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization.

Peter Schmidt, A. Zuse, Eberhard Unger, 2007, Journal of medicinal chemistry.

Photosynthesis Inhibitors: Regulatory Aspects, Reregistration in Europe, Market Trends, and New Products

K. Müller, Karl-Wilhelm Münks, 2008 .

Medicinal plants from Nepal; II. Evaluation as inhibitors of lipid peroxidation in biological membranes.

K. Müller, Sunil Kumar KC, 1999, Journal of ethnopharmacology.

Treatment of psoriasis with anthrones-chemical principles, biochemical aspects, and approaches to the design of novel derivatives.

W. Wiegrebe, K. Müller, 1995, Skin pharmacology : the official journal of the Skin Pharmacology Society.

2-arylalkyl-substituted anthracenones as inhibitors of 12-lipoxygenase enzymes. 1. Structure-activity relationships of the terminal aryl ring.

R. Altmann, H. Prinz, K. Müller, 2001, European journal of medicinal chemistry.

Synthesis and biological evaluation of novel 10-benzyl-substituted 4,5-dichloro-10H-anthracen-9-ones as inhibitors of keratinocyte hyperproliferation.

H. Prinz, K. Müller, Ulrich Kratz, 2010, European journal of medicinal chemistry.

Acetohydroxyacid Synthase Inhibitors (AHAS/ALS)

D. Shaner, Bijay Singh, S. Gutteridge, 2012 .

BAY MKH 6561 - a new selective herbicide for grass control in wheat, rye and triticale.

H. Santel, K. Müller, D. Feucht, 1999 .

Inhibition of leukotriene biosynthesis and lipid peroxidation in biological models by the extract of Cassia fistula

K. Müller, S. K. C., 1998 .

Antipsoriatic anthrones with modulated redox properties. 3. 10-thio-substituted 1,8-dihydroxy-9(10H)-anthracenones as inhibitors of keratinocyte growth, 5-lipoxygenase, and the formation of 12(S)-HETE in mouse epidermis.

H. Huang, W. Wiegrebe, K. Müller, 1996, Journal of medicinal chemistry.

Reduction of nitroxides by anthralin and some of its derivatives.

M. Schara, W. Wiegrebe, K. Müller, 1995, Free Radical Biology & Medicine.

Dimethyl 3,3′‐(4‐Methyl‐1,3‐naphthylene)dipropionate as a Singlet Oxygen Trap in Biological Systems

K. Müller, K. Ziereis, 1993 .

10-Benzoyl-1,8-dihydroxy-9(10H)-anthracenones: Synthesis and biological properties

R. Altmann, H. Prinz, K. Müller, 1998 .

Antipsoriatic anthrones with modulated redox properties. 1. Novel 10-substituted 1,8-dihydroxy-9(10H)-anthracenones as inhibitors of 5-lipoxygenase.

W. Wiegrebe, K. Müller, D. Gürster, 1993, Journal of medicinal chemistry.

Dithranol and active oxygen species, II. 1O2‐oxidation of dithranol to Chrysazin

W. Wiegrebe, K. Müller, K. Mayer, 1986 .

Cornified Envelope Formation by Anthralin, Simple Analogues, and Related Anthracenones

K. Müller, H. Reindl, 2001, Archiv der Pharmazie.

10-Phenylbutyryl-substituted anthracenones as inhibitors of keratinocyte growth and LTB(4) biosynthesis.

K. Müller, H. Reindl, K. Breu, 2001, European journal of medicinal chemistry.

Heterocyclic substituted anthralin derivatives as inhibitors of keratinocyte growth and inducers of differentiation.

K. Müller, H. Reindl, K. Breu, 2001, Bioorganic & medicinal chemistry letters.

Inhibition of keratinocyte growth by different Nepalese Zanthoxylum species

Sunil Kumar, S. Kumar, K. Müller, 1999, Phytotherapy research : PTR.

10-omega-phenylalkyl-9(10H)-anthracenones as inhibitors of keratinocyte growth with reduced membrane damaging properties.

K. Müller, K. Breu, 1998, Bioorganic & medicinal chemistry letters.

Dithranol, Singlet Oxygen and Unsaturated Fatty Acids

W. Wiegrebe, K. Müller, K. Mayer, 1986 .

Naphthalenes as Water‐Soluble Singlet Oxygen Carriers and Detectors: Hydrophobic and Kinetic Properties

K. Müller, K. Ziereis, 1992 .

KINETIC STUDIES ON ANTHRALIN PHOTOOXIDATION

C. Foote, K. Müller, R. Kanner, 1990, Photochemistry and photobiology.

N-benzoylated phenoxazines and phenothiazines: synthesis, antiproliferative activity, and inhibition of tubulin polymerization.

M. Gerlach, K. Böhm, H. Prinz, 2011, Journal of medicinal chemistry.

Modulation of Pharmacologically Relevant Properties of Piperidine Derivatives by Functional Groups in an Equatorial or Axial β‐Position to the Amino Group

Rainer E. Martin, Björn Wagner, H. Fischer, 2020, Chembiochem : a European journal of chemical biology.

Benzophenanthridine alkaloids of Chelidonium majus; I. Inhibition of 5- and 12-lipoxygenase by a non-redox mechanism.

K. Müller, I. Gawlik, C. Vavrecková, 1996, Planta medica.

Benzophenanthridine alkaloids of Chelidonium majus; II. Potent inhibitory action against the growth of human keratinocytes.

K. Müller, I. Gawlik, C. Vavrecková, 1996, Planta medica.

The Composition-Dependent Presence of Free (Micellar) Alkylphospholipid in Liposomal Formulations of Octadecyl-1,1-dimethyl-piperidino-4-yl-phosphate Affects its Cytotoxic Activity in vitro

A. Fahr, N. Maurer, R. Zeisig, 2001, The Journal of Membrane Biology.

The herbicide binding niche of photosystem II‐a model

K. Tietjen, A. Trebst, J. Kluth, 1991 .

Inhibition of triosephosphate isomerase from Trypanosoma brucei with cyclic hexapeptides.

F. Opperdoes, H. Kessler, R. Wierenga, 1992, European journal of biochemistry.

Structure-activity relationship studies of acridones as potential antipsoriatic agents. 1. Synthesis and antiproliferative activity of simple N-unsubstituted 10H-acridin-9-ones against human keratinocyte growth.

H. Prinz, K. Müller, Aleksandar Putic, 2010, European journal of medicinal chemistry.

10-(4-Phenylpiperazine-1-carbonyl)acridin-9(10H)-ones and Related Compounds: Synthesis, Antiproliferative Activity and Inhibition of Tubulin Polymerization.

Jahan B. Ghasemi, E. Aghaee, H. Prinz, 2020, Bioorganic & medicinal chemistry letters.

Antipsoriatic anthrones with modulated redox properties. 2. Novel derivatives of chrysarobin and isochrysarobin--antiproliferative activity and 5-lipoxygenase inhibition.

P. Leukel, K. Müller, K. Ziereis, 1994, Journal of medicinal chemistry.

Current status and recent developments in anthracenone antipsoriatics.

K. Müller, 2000, Current pharmaceutical design.

Novel 10-substituted antipsoriatic anthrones as inhibitors of epidermal 12-lipoxygenase and lipid peroxidation in membranes.

K. Müller, I. Gawlik, 1995, Biochemical pharmacology.

Acidity and Stability of 10‐Substituted 1,8‐Dihydroxy‐9(10H)‐anthracenones

W. Wiegrebe, K. Müller, I. Gawlik, 1995 .

A Convenient Synthesis of 14C‐Anthralin

Hsu-Shan Huang, W. Wiegrebe, K. Müller, 1994 .

A promising naphthoquinone [8-hydroxy-2-(2-thienylcarbonyl)naphtho[2,3-b]thiophene-4,9-dione] exerts anti-colorectal cancer activity through ferroptosis and inhibition of MAPK signaling pathway based on RNA sequencing

K. Müller, Daneiva C Caro, Y. Ocampo, 2020 .

Pharmaceutically relevant metabolites from lichens

K. Müller, K. Müller, 2001, Applied Microbiology and Biotechnology.

N-benzoylated phenoxazines and phenothiazines: synthesis, antiproliferative activity, and inhibition of tubulin polymerization.

M. Gerlach, K. Böhm, H. Prinz, 2011, Journal of medicinal chemistry.

Medicinal plants from nepal: evaluation as inhibitors of leukotriene biosynthesis.

W. Wiegrebe, S. Kumar, K. Müller, 2000, Journal of ethnopharmacology.