Y. Gladilina

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Mechanisms of Development of Side Effects and Drug Resistance to Asparaginase and Ways to Overcome Them

M. Pokrovskaya, N. N. Sokolov, D. Zhdanov, 2022, Biochemistry (Moscow), Supplement Series B: Biomedical Chemistry.

Phenotypical and Functional Characteristics of Human Regulatory T Cells during Ex Vivo Maturation from CD4+ T Lymphocytes

D. Zhdanov, Y. Gladilina, A. Hilal, 2021, Applied Sciences.

Inhibition of telomerase activity by splice-switching oligonucleotides targeting the mRNA of the telomerase catalytic subunit affects proliferation of human CD4+ T lymphocytes.

D. V. Grishin, M. Pokrovskaya, V. Pokrovsky, 2019, Biochemical and biophysical research communications.

Contact‐independent suppressive activity of regulatory T cells is associated with telomerase inhibition, telomere shortening and target lymphocyte apoptosis

D. V. Grishin, M. Pokrovskaya, V. Pokrovsky, 2018, Molecular immunology.

Induction of Alternative Splicing and Inhibition of Activity of Telomerase Catalytic Subunit by Apoptotic Endonuclease EndoG in Human T, B, and NK Cells

D. V. Grishin, M. Pokrovskaya, O. Podobed, 2018, Bulletin of Experimental Biology and Medicine.

Inhibition of telomerase activity and induction of apoptosis by Rhodospirillum rubrum l‐asparaginase in cancer Jurkat cell line and normal human CD4+ T lymphocytes

D. V. Grishin, M. Pokrovskaya, O. Podobed, 2017, Cancer medicine.

Rhodospirillum rubruml-asparaginase targets tumor growth by a dual mechanism involving telomerase inhibition.

D. V. Grishin, M. Pokrovskaya, O. Podobed, 2017, Biochemical and biophysical research communications.

Increased Suppressor Activity of Ex Vivo Transformed Regulatory T Cells in Comparison with Unstimulated Cells of the Same Donor

D. Zhdanov, Y. Gladilina, D. D. Eliseeva, 2022, Biochemistry (Moscow), Supplement Series B: Biomedical Chemistry.

A Pilot Study on an Electrochemical Approach for Assessing Transient DNA Transfection in Eukaryotic Cells

V. Shumyantseva, Y. Gladilina, S. Kanashenko, 2022, Journal of Electroanalytical Chemistry.

Creation of thermostable polypeptide cassettes for amino acid balancing in farm animal rations

D. V. Grishin, M. Pokrovskaya, O. Podobed, 2017, Applied Biochemistry and Microbiology.

[Induction of apoptotic endonuclease EndoG with DNA-damaging agents initiates alternative splicing of telomerase catalytic subunit hTERT and inhibition of telomerase activity hTERT in human CD4+ and CD8+ T-lymphocytes].

D. V. Grishin, E. Orlova, M. Pokrovskaya, 2017, Biomeditsinskaia khimiia.

New Genetic Bomb Trigger: Design, Synthesis, Molecular Dynamics Simulation, and Biological Evaluation of Novel BIBR1532-Related Analogs Targeting Telomerase against Non-Small Cell Lung Cancer

A. Veselovsky, D. Zhdanov, Y. Gladilina, 2022, Pharmaceuticals.

Thermostable Recombinant Polypeptides as the Source of L-Amino Acids for Culture Media

D. V. Grishin, M. Pokrovskaya, O. Podobed, 2018, Bulletin of Experimental Biology and Medicine.

Thermostable Recombinant Polypeptides as the Source of L-Amino Acids for Culture Media

D. V. Grishin, M. Pokrovskaya, O. Podobed, 2018, Bulletin of Experimental Biology and Medicine.

Apoptotic Endonuclease EndoG Induces Alternative Splicing of Telomerase TERT Catalytic Subunit, Caspase-2, DNase I, and BCL-x in Human, Murine, and Rat CD4+ T Lymphocytes

D. V. Grishin, M. Pokrovskaya, V. Pokrovsky, 2018, Russian Journal of Bioorganic Chemistry.

Murine regulatory T cells induce death of effector T, B, and NK lymphocytes through a contact-independent mechanism involving telomerase suppression and telomere-associated senescence.

D. V. Grishin, M. Pokrovskaya, V. Pokrovsky, 2018, Cellular immunology.

[Bioactive proteins and peptides: current state and new trends of practical application in the food industry and feed production].

D. V. Grishin, M. Pokrovskaya, O. Podobed, 2017, Voprosy pitaniia.

Mechanisms of the Antiproliferative and Antitumor Activity of Novel Telomerase-Carbonic Anhydrase Dual-Hybrid Inhibitors.

C. Supuran, M. Ferraroni, A. Veselovsky, 2021, Journal of medicinal chemistry.

Characteristics of Tumors That Develop in Athymic Mice after Transplantation of Human Malignant CD4+ T-lymphocytes Transformed ex vivo

D. V. Grishin, M. Pokrovskaya, V. Pokrovsky, 2019, Cell and Tissue Biology.

Induction of Telomerase Catalytic Subunit Alternative Splicing by Apoptotic Endonuclease G in Mouse and Rat Lymphocytes

D. V. Grishin, M. Pokrovskaya, O. Podobed, 2018 .

Induction of Telomerase Catalytic Subunit Alternative Splicing by Apoptotic Endonuclease G in Mouse and Rat Lymphocytes

D. V. Grishin, M. Pokrovskaya, O. Podobed, 2018, Cell and Tissue Biology.

Induction of Alternative Splicing and Inhibition of Activity of Telomerase Catalytic Subunit by Apoptotic Endonuclease EndoG in Human T, B, and NK Cells

D. V. Grishin, M. Pokrovskaya, O. Podobed, 2018, Bulletin of experimental biology and medicine.

Cytoprotective Activity of Polyamines Is Associated with the Alternative Splicing of RAD51A Pre-mRNA in Normal Human CD4+ T Lymphocytes

E. V. Neborak, D. Zhdanov, Y. Gladilina, 2022, International journal of molecular sciences.

Endonuclease G modulates the alternative splicing of deoxyribonuclease 1 mRNA in human CD4+ T lymphocytes and prevents the progression of apoptosis.

D. V. Grishin, M. Pokrovskaya, V. Pokrovsky, 2019, Biochimie.

[Approaches for improving L-asparaginase expression in heterologous systems].

D. Zhdanov, Y. Gladilina, A. N. Shishparenok, 2023, Biomeditsinskaia khimiia.

Inhibition of nuclease activity by a splice-switching oligonucleotide targeting deoxyribonuclease 1 mRNA prevents apoptosis progression and prolong viability of normal human CD4+ T-lymphocytes.

M. Pokrovskaya, V. Pokrovsky, D. Zhdanov, 2020, Biochimie.

Apoptotic Endonuclease EndoG Induces Alternative Splicing of Telomerase TERT Catalytic Subunit, Caspase-2, DNase I, and BCL-x in Human, Murine, and Rat CD4+ T Lymphocytes

D. V. Grishin, M. Pokrovskaya, V. Pokrovsky, 2018, Russian Journal of Bioorganic Chemistry.

Cloning, expression, and purification of Helicobacter pylori L-asparaginase

N. Sokolov, Y. Gladilina, J. V. Krasotkina, 2009, Biomeditsinskaia khimiia.

Modulation of Suppressive Activity and Proliferation of Human Regulatory T Cells by Splice-Switching Oligonucleotides Targeting FoxP3 Pre-mRNA

Y. Gladilina, D. D. Eliseeva, V. Vtorushina, 2023, Cells.

Engineering and Expression Strategies for Optimization of L-Asparaginase Development and Production

Y. Gladilina, A. N. Shishparenok, D. Zhdanov, 2023, International journal of molecular sciences.