Huiping Zhang

发表

Highly regioselective ruthenium-catalyzed direct arylation of thiazolo[3,2-b]-1,2,4-triazoles with aryl iodides and aryl bromides via C–H bond activation

Huiping Zhang, 2014 .

Discovery and Preclinical Evaluation of BMS-711939, an Oxybenzylglycine Based PPARα Selective Agonist.

M. Blanar, Rongan Zhang, S. Krystek, 2016, ACS medicinal chemistry letters.

Synthesis of ethyl 3-phenyl-4-(trifluoromethyl)isoxazole-5-carboxylate via regioselective dipolar cycloaddition

Antonio Ramirez, O. Soltani, Michael A. Schmidt, 2012 .

The effect of water on the large-scale supercritical fluid chromatography purification of two factor XIa active pharmaceutical ingredients.

A. Mathur, Dawn Sun, Dauh-Rurng Wu, 2021, Journal of chromatography. A.

Discovery and Preclinical Pharmacology of an Oral Bromodomain and Extra-Terminal (BET) Inhibitor Using Scaffold-Hopping and Structure-Guided Drug Design.

Vijay T. Ahuja, Derek J. Norris, J. Tokarski, 2021, Journal of medicinal chemistry.

BMS-986163, a Negative Allosteric Modulator of GluN2B with Potential Utility in Major Depressive Disorder.

J. Macor, A. Mathur, B. Srikumar, 2018, ACS medicinal chemistry letters.

PYRANOSIDE ALKENE TEMPLATES FOR THE SYNTHESIS OF CIS-2,5-DISUBSTITUTED TETRAHYDROFURAN SUBUNITS OF THE ACETOGENINS

D. R. Mootoo, Huiping Zhang, Galyna Pushchinska, 2002 .

Discovery of Milvexian, a High-Affinity, Orally Bioavailable Inhibitor of Factor XIa in Clinical Studies for Antithrombotic Therapy.

Michael A. Galella, S. Sheriff, A. Mathur, 2021, Journal of medicinal chemistry.

An Efficient Scale-Up Synthesis of BMS-520, a Potent and Selective Isoxazole-Containing S1P1 Receptor Agonist

A. Mathur, W. Pitts, P. Carter, 2016 .

Small Molecule Reversible Inhibitors of Bruton's Tyrosine Kinase (BTK): Structure-Activity Relationships Leading to the Identification of 7-(2-Hydroxypropan-2-yl)-4-[2-methyl-3-(4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]-9H-carbazole-1-carboxamide (BMS-935177).

K. McIntyre, J. Barrish, A. Mathur, 2016, Journal of medicinal chemistry.

Evolution of a Scale-Up Synthesis to a Potent GluN2B Inhibitor and Its Prodrug

Michael A. Galella, A. Mathur, M. Dabros, 2018, Organic Process Research & Development.

Discovery of a Parenteral Small Molecule Coagulation Factor XIa Inhibitor Clinical Candidate (BMS-962212).

P. Lam, S. Sheriff, A. Mathur, 2017, Journal of medicinal chemistry.

Tetrabutylammonium Pyridin-2-olate: A New Reagent for the Efficient Synthesis of N-Aryl Pyridin-2-ones

S. Chao, Bang-Chi Chen, R. Zhao, 2008 .

Microwave-Assisted Solvent-Free Synthesis of Imidazo[1,2-a]pyridines via a Three-Component Reaction.

Linlin Jiang, Huiping Zhang, 2015 .

A Novel Synthesis of (E)-3-Methylthio-3-Substituted Arylamino-2-Cyanoacrylates under Microwave Irradiation

B. Song, D. Hu, Linhong Jin, 2005, Molecules.

A Novel One-Pot Multicomponent Enzymatic Synthesis of 2,4-Disubstituted Thiazoles

Huiping Zhang, 2014, Catalysis Letters.

Synthesis and antiviral activities of novel chiral cyanoacrylate derivatives with (E) configuration.

Pinaki S. Bhadury, Jun Wang, B. Song, 2008, Bioorganic & medicinal chemistry.

cis-2,5-Disubstituted tetrahydrofurans from pyranosides: A novel example of remote stereocontrol by the aglycone

Weifang Shan, D. R. Mootoo, Huiping Zhang, 1995 .

Regioselective Epoxide Ring Opening for the Stereospecific Scale-Up Synthesis of BMS-960, A Potent and Selective Isoxazole-Containing S1P1 Receptor Agonist

A. Mathur, Zhiwei Guo, A. Goswami, 2017 .

ACETAL TEMPLATES FOR THE SYNTHESIS OF TRANS-2,5-DISUBSTITUTED TETRAHYDROFURANS

D. R. Mootoo, Huiping Zhang, 1995 .

Asymmetric Dihydroxylation−Haloetherification Strategy for the Synthesis of Tetrahydrofuran-Containing Acetogenins†

D. R. Mootoo, Sheila Seepersaud, Huiping Zhang, 1998 .

Sulfuryl Transfer: The Catalytic Mechanism of Human Estrogen Sulfotransferase*

C. Falany, T. Leyh, F. Vargas, 1998, The Journal of Biological Chemistry.

Large-scale supercritical fluid chromatography purification of unstable STING agonist intermediates.

A. Mathur, Dawn Sun, Dauh-Rurng Wu, 2021, Journal of chromatography. A.

Large‐scale chiral supercritical fluid chromatography of a key intermediate in the synthesis of two S1P 1 final active pharmaceutical ingredients

A. Mathur, P. Li, Dawn Sun, 2019, SEPARATION SCIENCE PLUS.

Novel antifungal diketopiperazine from marine fungus.

Y. Shizuri, K. Adachi, H. Byun, 2003, The Journal of antibiotics.

Small molecule antagonist of leukocyte function associated antigen-1 (LFA-1): structure-activity relationships leading to the identification of 6-((5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-7-yl)nicotinic acid (BMS-688521).

P. M. Davis, K. McIntyre, J. Barrish, 2010, Journal of medicinal chemistry.

Discovery of Highly Potent Liver X Receptor β Agonists

A. D. Rodrigues, P. Sleph, T. Kirchgessner, 2016, ACS medicinal chemistry letters.

A facile and efficient synthesis of d3‐labelled Reyataz™

J. Barrish, L. Leith, S. Bonacorsi, 2005 .

Discovery of an oxybenzylglycine based peroxisome proliferator activated receptor alpha selective agonist 2-((3-((2-(4-chlorophenyl)-5-methyloxazol-4-yl)methoxy)benzyl)(methoxycarbonyl)amino)acetic acid (BMS-687453).

Wei Wang, Jun Li, Ying Wang, 2010, Journal of medicinal chemistry.

Synthesis of d3-cerivastatin for use as internal standard in a LC/MS/MS method developed for quantitation of the drug in human serum

J. Barrish, M. Jemal, J. Robl, 2006 .

Preclinical Characterization of (R)-3-((3S,4S)-3-fluoro-4-(4-hydroxyphenyl)piperidin-1-yl)-1-(4-methylbenzyl)pyrrolidin-2-one (BMS-986169), a Novel, Intravenous, Glutamate N-Methyl-d-Aspartate 2B Receptor Negative Allosteric Modulator with Potential in Major Depressive Disorder

J. Macor, A. Mathur, B. Srikumar, 2017, The Journal of Pharmacology and Experimental Therapeutics.