V. Atigadda

发表

Pyrrolidinobenzoic acid inhibitors of influenza virus neuraminidase: modifications of essential pyrrolidinone ring substituents.

G. Air, M. Luo, S. Velu, 2003, Bioorganic & medicinal chemistry.

A novel retinoid X receptor agonist, UAB30, inhibits rhabdomyosarcoma cells in vitro.

E. Beierle, C. Grubbs, J. Stewart, 2018, The Journal of surgical research.

Conformationally defined retinoic acid analogues. 5. Large-scale synthesis and mammary cancer chemopreventive activity for (2E,4E,6Z,8E)-8-(3',4'-dihydro-1'(2'H)-naphthalen-1'-ylidene)-3,7-dimethyl-2,4,6-octatrienoic acid (9cUAB30).

K. Bland, C. Grubbs, D. Hill, 2003, Journal of medicinal chemistry.

Detection of Serotonin, Melatonin, and Their Metabolites in Honey.

R. Reiter, A. Slominski, R. Tuckey, 2021, ACS food science & technology.

UAB30, A Novel Rexinoid Agonist, Decreases Stemness In Group 3 Medulloblastoma Human Cell Line Xenografts

E. Beierle, Raoud Marayati, B. P. Moore, 2019, Translational oncology.

UAB30, a novel RXR agonist, decreases tumorigenesis and leptomeningeal disease in group 3 medulloblastoma patient-derived xenografts

A. Hjelmeland, E. Beierle, L. Nan, 2018, Journal of Neuro-Oncology.

9-cis-UAB30, a novel rexinoid agonist, decreases tumorigenicity and cancer cell stemness of human neuroblastoma patient-derived xenografts

E. Beierle, Raoud Marayati, J. Stewart, 2020, Translational oncology.

Novel retinoic acid derivative induces differentiation and growth arrest in neuroblastoma.

E. Beierle, Raoud Marayati, J. Stewart, 2020, Journal of pediatric surgery.

The retinoid X receptor agonist, 9-cis UAB30, inhibits cutaneous T-cell lymphoma proliferation through the SKP2-p27kip1 axis.

C. Elmets, R. Dummer, I. Eto, 2018, Journal of dermatological science.

A Novel RXR Agonist, UAB30, Inhibits Rhabdomyosarcoma Cells in Vitro

C. Grubbs, J. Stewart, E. Mroczek-Musulman, 2018 .

Preclinical Evaluation of UAB30 in Pediatric Renal and Hepatic Malignancies

E. Beierle, C. Grubbs, J. Stewart, 2016, Molecular Cancer Therapeutics.

Retinoid X Receptor Agonists Upregulate Genes Responsible for the Biosynthesis of All-Trans-Retinoic Acid in Human Epidermis

C. Elmets, M. Athar, N. Kedishvili, 2016, PloS one.

Preclinical Evaluation of a Novel RXR Agonist for the Treatment of Neuroblastoma

E. Beierle, C. Grubbs, J. Stewart, 2015, Molecular Cancer Therapeutics.

Novel second-generation rexinoid induces growth arrest and reduces cancer cell stemness in human neuroblastoma patient-derived xenografts.

E. Beierle, Raoud Marayati, J. Stewart, 2021, Journal of pediatric surgery.

Determination of ergovaline in tall fescue by a specific monoclonal antibody

F. Smith, R. Shelby, R. Bridgman, 1998 .

Stability of the Retinoid X Receptor-α Homodimer in the Presence and Absence of Rexinoid and Coactivator Peptide.

M. Renfrow, Zhengrong Yang, D. Muccio, 2021, Biochemistry.

Conformationally Defined Rexinoids and Their Efficacy in the Prevention of Mammary Cancers.

K. Bland, Craig D. Smith, H. Krontiras, 2015, Journal of medicinal chemistry.

Metabolic activation of tachysterol3 to biologically active hydroxyderivatives that act on VDR, AhR, LXRs, and PPARγ receptors

A. Jetten, A. Slominski, C. Raman, 2022, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Detection of 7-Dehydrocholesterol and Vitamin D3 Derivatives in Honey

A. Slominski, R. Tuckey, Tae-Kang Kim, 2020, Molecules.

Advances in molecular pathogenesis of hidradenitis suppurativa: Dysregulated keratins and ECM signaling.

M. S. Mukhtar, C. Elmets, M. Athar, 2022, Seminars in cell & developmental biology.

Ex Vivo Culture Models of Hidradenitis Suppurativa for Defining Molecular Pathogenesis and Treatment Efficacy of Novel Drugs

M. S. Mukhtar, Z. Weng, C. Elmets, 2021, Inflammation.

Novel retinoic acid derivative induces differentiation and growth arrest in neuroblastoma.

E. Beierle, Raoud Marayati, J. Stewart, 2019, Journal of pediatric surgery.

Conformationally Defined Rexinoids for the Prevention of Inflammation and Nonmelanoma Skin Cancers.

C. Elmets, M. Athar, D. Chattopadhyay, 2022, Journal of medicinal chemistry.

Translation of a Tissue-Selective Rexinoid, UAB30, to the Clinic for Breast Cancer Prevention.

K. Bland, H. Krontiras, C. Grubbs, 2017, Current topics in medicinal chemistry.

Next-generation retinoid X receptor agonists increase ATRA signaling in organotypic epithelium cultures and have distinct effects on receptor dynamics

C. Elmets, M. Kane, L. Nagy, 2022, The Journal of biological chemistry.

Design of benzoic acid inhibitors of influenza neuraminidase containing a cyclic substitution for the N-acetyl grouping.

G. Air, M. Luo, W. Brouillette, 1999, Bioorganic & medicinal chemistry letters.

Potent inhibition of influenza sialidase by a benzoic acid containing a 2-pyrrolidinone substituent.

G. Air, M. Luo, D. A. Walsh, 1999, Journal of medicinal chemistry.

Global molecular changes in rat livers treated with RXR agonists: a comparison using transcriptomics and proteomics

M. You, K. Bland, R. Lubet, 2014 .

Efficacy of new retinoids in the prevention of mammary cancers and correlations with short-term biomarkers.

K. Bland, K. Christov, R. Lubet, 2006, Carcinogenesis.

A Small Molecule, UAB126, Reverses Diet-Induced Obesity and its Associated Metabolic Disorders

M. Bjornsti, S. Frank, A. Shalev, 2020, Diabetes.

Chemical synthesis, biological activities and action on nuclear receptors of 20S(OH)D3, 20S,25(OH)2D3, 20S,23S(OH)2D3 and 20S,23R(OH)2D3.

A. Jetten, A. Slominski, C. Raman, 2022, Bioorganic chemistry.

Vitamin D and lumisterol derivatives can act on liver X receptors (LXRs)

J. Chen, D. Crossman, A. Jetten, 2021, Scientific Reports.

The impact of novel retinoids in combination with platinum chemotherapy on ovarian cancer stem cells.

P. Oliver, J. Sellers, D. Buchsbaum, 2012, Gynecologic oncology.

Stability of the Retinoid X Receptor-alpha Homodimer in the Presence and Absence of Rexinoid and Coactivator Peptide

M. Renfrow, Zhengrong Yang, D. Muccio, 2020, bioRxiv.

The Use of Retinoids in Ovarian Cancer: A Review of the Literature

D. Buchsbaum, J. Straughn, D. Muccio, 2011, International Journal of Gynecologic Cancer.

Novel aromatic inhibitors of influenza virus neuraminidase make selective interactions with conserved residues and water molecules in the active site.

G. Air, M. Luo, F. Duarte, 1999, Journal of molecular biology.

Hydrophobic benzoic acids as inhibitors of influenza neuraminidase.

G. Air, M. Luo, D. A. Walsh, 1999, Bioorganic & medicinal chemistry.

9cUAB30, an RXR specific retinoid, and/or tamoxifen in the prevention of methylnitrosourea-induced mammary cancers.

K. Bland, I. Eto, C. Grubbs, 2003, Cancer letters.

Mechanism underlying follicular hyperproliferation and oncogenesis in hidradenitis suppurativa

Z. Weng, B. Elewski, C. Elmets, 2023, iScience.

Retinoid X Receptor Activation Prevents Diabetic Retinopathy in Murine Models

O. Gorbatyuk, M. Gorbatyuk, V. Atigadda, 2023, Cells.

Retinoid X Receptor activation prevents diabetic retinopathy in murine models

M. Grant, I. Saltykova, O. Gorbatyuk, 2023, bioRxiv.

UAB30, A Novel Rexinoid Agonist, Decreases Stemness In Group 3 Medulloblastoma Human Cell Line Xenografts

E. Beierle, Raoud Marayati, B. P. Moore, 2019, Translational oncology.

Melatonin and Its Metabolites Can Serve as Agonists on the Aryl Hydrocarbon Receptor and Peroxisome Proliferator-Activated Receptor Gamma

C. Elferink, K. Kleszczyński, R. Slominski, 2023, International journal of molecular sciences.

Methyl Substitution of a Rexinoid Agonist Improves Potency and Reveals Site of Lipid Toxicity

Craig D. Smith, C. Grubbs, W. Brouillette, 2014, Journal of medicinal chemistry.

Methyl-substituted conformationally constrained rexinoid agonists for the retinoid X receptors demonstrate improved efficacy for cancer therapy and prevention.

Craig D. Smith, K. Christov, Fariba L Moeinpour, 2014, Bioorganic & medicinal chemistry.