S. Hamuľaková

发表

Targeting copper(II)-induced oxidative stress and the acetylcholinesterase system in Alzheimer's disease using multifunctional tacrine-coumarin hybrid molecules.

K. Kuča, D. Jun, M. Valko, 2016, Journal of inorganic biochemistry.

Novel tacrine/acridine anticholinesterase inhibitors with piperazine and thiourea linkers.

S. Böhm, K. Kuča, M. Pohanka, 2014, International journal of biological macromolecules.

In vitro investigating of anticancer activity of new 7-MEOTA-tacrine heterodimers

K. Kuča, V. Brabec, J. Kašpárková, 2019, Journal of enzyme inhibition and medicinal chemistry.

Tacrine derivatives as dual topoisomerase I and II catalytic inhibitors.

V. Brabec, J. Kašpárková, P. Fedoročko, 2015, Bioorganic chemistry.

Synthesis of New Biscoumarin Derivatives, In Vitro Cholinesterase Inhibition, Molecular Modelling and Antiproliferative Effect in A549 Human Lung Carcinoma Cells

K. Kuča, P. Fedoročko, D. Jun, 2021, International journal of molecular sciences.

Tacrine-Coumarin Derivatives as Topoisomerase Inhibitors with Antitumor Effects on A549 Human Lung Carcinoma Cancer Cell Lines

P. Fedoročko, R. Jendželovský, M. Kožurková, 2021, Molecules.

Neuroactive Multifunctional Tacrine Congeners with Cholinesterase, Anti-Amyloid Aggregation and Neuroprotective Properties

P. Kristian, Z. Gazova, M. Kožurková, 2011, Pharmaceuticals.

Synthesis and biological evaluation of novel tacrine derivatives and tacrine-coumarin hybrids as cholinesterase inhibitors.

K. Kuča, J. Imrich, P. Kristian, 2014, Journal of medicinal chemistry.

Synthesis, design and biological evaluation of novel highly potent tacrine congeners for the treatment of Alzheimer's disease.

Martina Hrabinova, Kamil Kuca, Ladislav Janovec, 2012, European journal of medicinal chemistry.

Coumarin Derivatives in Pharmacotherapy of Alzheimer´s Disease

K. Kuča, M. Kožurková, S. Hamuľaková, 2017 .

Proliferation inhibition of novel diphenylamine derivatives.

J. Imrich, J. Janockova, M. Kožurková, 2019, Bioorganic chemistry.

Inhibition of DNA topoisomerases I and II and growth inhibition of HL-60 cells by novel acridine-based compounds.

K. Kuča, V. Brabec, J. Kašpárková, 2015, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Synthesis, structure, and cholinergic effect of novel neuroprotective compounds bearing the tacrine pharmacophore

S. Böhm, K. Kuča, D. Jun, 2008 .

Interaction of tacrine-coumarin derivatives with double stranded DNA: spectroscopic and molecular docking study

M. Kožurková, S. Hamuľaková, E. Konkoľová, 2023, Chemical Papers.

Lysozyme amyloid fibrillization in presence of tacrine/acridone-coumarin heterodimers.

Josephine W. Wu, Z. Bednarikova, Z. Gazova, 2018, Colloids and surfaces. B, Biointerfaces.

Synthesis, in vitro acetylcholinesterase inhibitory activity and molecular docking of new acridine-coumarin hybrids.

K. Kuča, D. Jun, O. Soukup, 2017, International journal of biological macromolecules.

Synthesis of Acetylcholinesterase Inhibitors on the Basis of 9-Isothiocyanato-1,2,3,4-tetrahydroacridine: 2-[(1,2,3,4-Tetrahydroacridin-9-yl)imino]-3-substituted 1,3-Thiazolidin-4-ones

J. Imrich, P. Kristian, G. Voss, 1998 .

Tacrine-coumarin and Tacrine-7-chloroquinoline Hybrids with Thiourea Linkers: Cholinesterase Inhibition Properties, Kinetic Study, Molecular Docking and Permeability Assay for Blood-brain Barrier.

K. Kuča, D. Jun, O. Soukup, 2018, Current Alzheimer research.

Synthesis of Acetylcholinesterase Inhibitors on the Basis of 9-Isothiocyanato-1,2,3,4-tetrahydroacridine: 2-[(1,2,3,4-Tetrahydroacridin-9-yl)imino] -3-substituted-1,3-thiazolidin-4-ones (VI).

J. Imrich, P. Kristian, G. Voss, 1999 .

Design and synthesis of novel tacrine-indole hybrids as potential multitarget-directed ligands for the treatment of Alzheimer's disease.

K. Kuča, D. Jun, Y. Chernoff, 2021, Future medicinal chemistry.