Laura A Hargrove

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Updates on Dietary Models of Nonalcoholic Fatty Liver Disease: Current Studies and Insights.

G. Alpini, H. Francis, Lindsey Kennedy, 2017, Gene expression.

Dysregulation of vitamin D3 synthesis leads to enhanced cholangiocarcinoma growth.

J. Venter, F. Meng, H. Francis, 2013, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

Histamine restores biliary mass following carbon tetrachloride-induced damage in a cholestatic rat model.

Christopher P. Johnson, Y. Ueno, H. Francis, 2015, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

Tetrahydrobiopterin attenuates superoxide-induced reduction in nitric oxide.

Guoyao Wu, K. Kelly, C. Meininger, 2011, Frontiers in bioscience.

Mast Cells Promote Nonalcoholic Fatty Liver Disease Phenotypes and Microvesicular Steatosis in Mice Fed a Western Diet

S. Glaser, G. Alpini, F. Meng, 2021, Hepatology.

Biliary damage and liver fibrosis are ameliorated in a novel mouse model lacking l-histidine decarboxylase/histamine signaling

S. Glaser, G. Alpini, H. Francis, 2020, Laboratory Investigation.

Overexpression of membrane metalloendopeptidase inhibits substance P stimulation of cholangiocarcinoma growth.

Debolina Ray, S. Glaser, J. Venter, 2014, American journal of physiology. Gastrointestinal and liver physiology.

The emerging role of mast cells in liver disease.

H. Francis, Lindsey Kennedy, K. Stephenson, 2017, American journal of physiology. Gastrointestinal and liver physiology.

Knockout of microRNA-21 reduces biliary hyperplasia and liver fibrosis in cholestatic bile duct ligated mice

S. Glaser, J. Venter, G. Alpini, 2016, Laboratory Investigation.

Isolation and characterization of hepatic mast cells from cholestatic rats

Jennifer L Owens, H. Francis, Lindsey Kennedy, 2016, Laboratory Investigation.

Inhibition of mast cell-derived histamine secretion by cromolyn sodium treatment decreases biliary hyperplasia in cholestatic rodents

F. Meng, J. Greene, H. Francis, 2014, Laboratory Investigation.

Bile duct ligation–induced biliary hyperplasia, hepatic injury, and fibrosis are reduced in mast cell–deficient KitW‐sh mice

F. Meng, J. Greene, S. DeMorrow, 2017, Hepatology.

Inhibition of mast cell‐secreted histamine decreases biliary proliferation and fibrosis in primary sclerosing cholangitis Mdr2−/− mice

Christopher P. Johnson, G. Alpini, Jennifer L Owens, 2016, Hepatology.

Mast Cells Regulate Ductular Reaction and Intestinal Inflammation in Cholestasis Through Farnesoid X Receptor Signaling

S. Glaser, G. Alpini, B. Ekser, 2021, Hepatology.

Knockout of l-Histidine Decarboxylase Prevents Cholangiocyte Damage and Hepatic Fibrosis in Mice Subjected to High-Fat Diet Feeding via Disrupted Histamine/Leptin Signaling.

G. Alpini, J. M. Bailey, F. Meng, 2017, The American journal of pathology.

Downregulation of hepatic stem cell factor by Vivo-Morpholino treatment inhibits mast cell migration and decreases biliary damage/senescence and liver fibrosis in Mdr2-/- mice.

G. Alpini, S. Liangpunsakul, Zhihong Yang, 2019, Biochimica et biophysica acta. Molecular basis of disease.

Mast Cells Induce Ductular Reaction Mimicking Liver Injury in Mice Through Mast Cell–Derived Transforming Growth Factor Beta 1 Signaling

G. Alpini, F. Meng, H. Francis, 2021, Hepatology.

Ursodeoxycholate inhibits mast cell activation and reverses biliary injury and fibrosis in Mdr2−/− mice and human primary sclerosing cholangitis

G. Alpini, F. Meng, P. Invernizzi, 2018, Laboratory Investigation.

Histamine regulation of pancreatitis and pancreatic cancer: a review of recent findings.

H. Francis, Lindsey Kennedy, Laura A Hargrove, 2013, Hepatobiliary surgery and nutrition.

Alcoholic liver disease and mast cells: What's your gut got to do with it?

H. Francis, Lindsey Kennedy, Laura A Hargrove, 2019, Liver Research.

Vitamin D and GI cancers: shedding some light on dark diseases.

H. Francis, Laura A Hargrove, Taylor C Francis, 2014, Annals of translational medicine.

Recent Advances in Understanding Cholangiocarcinoma

H. Francis, Lindsey Kennedy, Laura A Hargrove, 2017, F1000Research.

Inhibition of Mast Cell-Derived Histamine Decreases Human Cholangiocarcinoma Growth and Differentiation via c-Kit/Stem Cell Factor-Dependent Signaling.

Christopher P. Johnson, G. Alpini, Jennifer L Owens, 2016, The American journal of pathology.

Mast cells (MCs) induce ductular reaction mimicking liver injury in mice via MC-derived TGF-β1 signaling.

G. Alpini, F. Meng, H. Francis, 2020, Hepatology.

Cellular crosstalk during cholestatic liver injury

H. Francis, Lindsey Kennedy, Laura A Hargrove, 2017, Liver research.

Amelioration of Large Bile Duct Damage by Histamine-2 Receptor Vivo-Morpholino Treatment

S. Glaser, G. Alpini, H. Francis, 2020, The American Journal of Pathology.

Blocking H1/H2 histamine receptors inhibits damage/fibrosis in Mdr2–/– mice and human cholangiocarcinoma tumorigenesis

G. Alpini, F. Meng, P. Invernizzi, 2018, Hepatology.

Knockout of histidine decarboxylase decreases bile duct ligation-induced biliary hyperplasia via downregulation of the histidine decarboxylase/VEGF axis through PKA-ERK1/2 signaling.

Y. Ueno, F. Meng, J. Greene, 2014, American journal of physiology. Gastrointestinal and liver physiology.

Regulation of the histamine/VEGF axis by miR-125b during cholestatic liver injury in mice.

P. Onori, E. Gaudio, Y. Ueno, 2014, The American journal of pathology.

Blocking H 1 / H 2 histamine receptors inhibits damage / fibrosis in Mdr 2-/-mice and human cholangiocarcinoma tumorigenesis Short title : Blocking H 1 / H 2 HRs reverses PSC and CCA damage

G. Alpini, F. Meng, P. Invernizzi, 2018 .

Prolonged intake of desloratadine: mesenteric lymphatic vessel dysfunction and development of obesity/metabolic syndrome.

Sarit Pal, Maria Troyanova-Wood, Cassidy Gobbell, 2019, American journal of physiology. Gastrointestinal and liver physiology.

Development and functional characterization of extrahepatic cholangiocyte lines from normal rats.

S. Glaser, J. Venter, G. Alpini, 2015, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

Knockout of Histidine Decarboxylase (HDC) Reduces Hepatic Fibrosis in Bile Duct Ligated (BDL) Mice

H. Francis, Laura A Hargrove, 2015 .

GASTROINTESTINAL , HEPATOBILIARY , AND PANCREATIC PATHOLOGY Regulation of the Histamine / VEGF Axis by miR-125 b during Cholestatic Liver Injury in Mice

P. Onori, E. Gaudio, Y. Ueno, 2014 .

H2 histamine receptor Vivo-Morpholino treatment ameliorates large bile duct damage in mice deficient in ATP binding cassette subfamily B member 4 (Abcb4-/-) via down-regulation of cAMP/ERK signaling.

S. Glaser, G. Alpini, H. Francis, 2020, The American journal of pathology.

Amelioration of Large Bile Duct Damage by Histamine-2 Receptor Vivo-Morpholino Treatment

S. Glaser, G. Alpini, H. Francis, 2022 .