N. Hernando

发表

The Voltage Dependence of a Cloned Mammalian Renal Type II Na+/Pi Cotransporter (NaPi-2)

H. Murer, J. Biber, I. Forster, 1998, The Journal of general physiology.

Renal phosphate handling and inherited disorders of phosphate reabsorption: an update

C. Wagner, I. Rubio-Aliaga, N. Hernando, 2019, Pediatric Nephrology.

Slc20a1/Pit1 and Slc20a2/Pit2 are essential for normal skeletal myofiber function and survival

C. Zeiss, G. Shulman, C. Wagner, 2020, Scientific Reports.

Protein/Protein Interactions (PDZ) in Proximal Tubules

H. Murer, J. Biber, N. Hernando, 2005, The Journal of Membrane Biology.

1,25(OH)2 vitamin D3 stimulates active phosphate transport but not paracellular phosphate absorption in mouse intestine

T. Knöpfel, C. Wagner, C. Bettoni, 2020, The Journal of physiology.

Gene panel sequencing identifies a likely monogenic cause in 7% of 235 Pakistani families with nephrolithiasis

T. Knöpfel, F. Hildebrandt, J. Sayer, 2019, Human Genetics.

Regulation of vitamin D metabolizing enzymes in murine renal and extrarenal tissues by dietary phosphate, FGF23, and 1,25(OH)2D3

C. Wagner, C. Bettoni, N. Hernando, 2018, PloS one.

NaPi‐IIa and interacting partners

N. Déliot, C. Wagner, O. Moe, 2005, The Journal of physiology.

Genetic diseases of renal phosphate handling.

C. Wagner, I. Rubio-Aliaga, J. Biber, 2014, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Genetic Defects in Renal Phosphate Handling

C. Wagner, H. Murer, J. Biber, 2009 .

Regulation of phosphate transport in proximal tubules

H. Murer, J. Biber, I. Forster, 2009, Pflügers Archiv: European Journal of Physiology.

Sodium-Dependent Phosphate Transporters in Osteoclast Differentiation and Function

C. Wagner, O. Bonny, M. Moor, 2015, PloS one.

Kidney kinase network regulates renal ion cotransport.

C. Wagner, H. Murer, J. Biber, 2007, The Journal of clinical investigation.

Molecular Characteristics of Phosphate Transporters and Their Regulation

H. Murer, J. Biber, I. Forster, 2000, Nephron Experimental Nephrology.

Isolation of a cDNA encoding a glutathione S-transferase (GST) class-pi from the bovine ocular ciliary epithelium.

N. Hernando, M. Coca‐Prados, J. Martín-Alonso, 1992, Experimental eye research.

Renal-specific and inducible depletion of NaPi-IIc/Slc34a3, the cotransporter mutated in HHRH, does not affect phosphate or calcium homeostasis in mice.

C. Wagner, H. Murer, R. Koesters, 2014, American journal of physiology. Renal physiology.

Amino acids involved in sodium interaction of murine type II Na+‐Pi cotransporters expressed in Xenopus oocytes

H. Murer, J. Biber, I. Forster, 2001, The Journal of physiology.

Molecular cloning of the bovine CD9 antigen from ocular ciliary epithelial cells.

N. Hernando, M. Coca‐Prados, J. Martín-Alonso, 1992, Journal of biochemistry.

Impaired phosphate transport in SLC34A2 variants in patients with pulmonary alveolar microlithiasis

T. Knöpfel, O. Hilberg, C. Wagner, 2022, Human genomics.

Regulation of sodium-proton exchanger isoform 3 (NHE3) by PKA and exchange protein directly activated by cAMP (EPAC).

C. Wagner, H. Murer, Katharina J. Honegger, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Endogenous digoxin-like immunoreactivity and erythrocyte sodium transport in uraemic patients undergoing dialysis.

J. López-Novoa, S. Casado, N. Hernando, 1989, Clinical science.

PTH-Induced downregulation of the type IIa Na/P(i)-cotransporter is independent of known endocytic motifs.

H. Murer, J. Biber, J. Forgo, 2000, Journal of the American Society of Nephrology : JASN.

Effect of Two Tyrosine Mutations on the Activity and Regulation of the Renal Type II Na/Pi-Cotransporter Expressed in Oocytes

M. Traebert, H. Murer, J. Biber, 1999, The Journal of Membrane Biology.

Renal localization and regulation by dietary phosphate of the MCT14 orphan transporter

T. Knöpfel, C. Wagner, A. Atanassoff, 2017, PloS one.

Mechanisms of phosphate transport

E. Gratton, C. Wagner, M. Levi, 2019, Nature Reviews Nephrology.

Alternative splicing generates a second isoform of the catalytic A subunit of the vacuolar H(+)-ATPase.

R. Baron, P. Collin‐Osdoby, P. Osdoby, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Proximal Tubular Handling of Phosphate

H. Murer, J. Biber, I. Forster, 2013 .

Novel aspects in regulated expression of the renal type IIa Na/Pi-cotransporter.

C. Wagner, B. Kaissling, H. Murer, 2004, Kidney international. Supplement.

The human pathogenic 91del7 mutation in SLC34A1 has no effect in mineral homeostasis in mice

C. Wagner, A. Daryadel, C. Bettoni, 2022, Scientific reports.

Molecular aspects in the regulation of renal inorganic phosphate reabsorption: the type IIa sodium/inorganic phosphate co-transporter as the key player

H. Murer, J. Biber, I. Forster, 2001, Current opinion in nephrology and hypertension.

Molecular determinants for apical expression of the renal type IIa Na+/Pi-cotransporter

H. Murer, J. Biber, N. Hernando, 2001, Pflügers Archiv.

Interactions of MAP17 with the NaPi-IIa/PDZK1 protein complex in renal proximal tubular cells.

H. Murer, A. Gantenbein, J. Biber, 2003, American journal of physiology. Renal physiology.

Interactions of MAP 17 with the NaPi-IIa / PDZK 1 protein complex in renal proximal tubular cells

H. Murer, A. Gantenbein, J. Biber, 2003 .

Recent Advances in Renal Phosphate Transport

H. Murer, J. Biber, I. Forster, 2005, Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy.

Parathyroid hormone treatment induces dissociation of type IIa Na+-P(i) cotransporter-Na+/H+ exchanger regulatory factor-1 complexes.

N. Déliot, C. Wagner, H. Murer, 2005, American journal of physiology. Cell physiology.

PDZ interactions and proximal tubular phosphate reabsorption.

C. Wagner, H. Murer, J. Biber, 2004, American journal of physiology. Renal physiology.

PDZ proteins and proximal ion transport

C. Wagner, H. Murer, J. Biber, 2004, Current opinion in nephrology and hypertension.

Regulation of Na/Pi transporter in the proximal tubule.

H. Murer, J. Biber, I. Forster, 2003, Annual review of physiology.

Molecular determinants for apical expression and regulatory membrane retrieval of the type IIa Na/Pi cotransporter.

H. Murer, J. Biber, N. Hernando, 2001, Kidney international.

Posttranscriptional regulation of the proximal tubule NaPi-II transporter in response to PTH and dietary Pi.

M. Traebert, H. Murer, J. Biber, 1999, American journal of physiology. Renal physiology.

Posttranscriptional regulation of the proximal tubule NaPi-II transporter in response to PTH and dietary Pi.

M. Traebert, H. Murer, J. Biber, 1999, American journal of physiology. Renal physiology.

Expression of phosphate and calcium transporters and their regulators in parotid glands of mice

C. Wagner, Betul Haykir, C. Bettoni, 2022, Pflügers Archiv - European Journal of Physiology.

A chronic high phosphate intake in mice is detrimental for bone health without major renal alterations.

C. Wagner, I. Rubio-Aliaga, N. Gehring, 2021, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Clinical, biochemical, and pathophysiological analysis of SLC34A1 mutations

V. Tasic, F. Hildebrandt, J. Sayer, 2018, Physiological reports.

Intestinal Depletion of NaPi‐IIb/Slc34a2 in Mice: Renal and Hormonal Adaptation

T. Knöpfel, C. Wagner, H. Murer, 2015, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

The intestinal phosphate transporter NaPi-IIb (Slc34a2) is required to protect bone during dietary phosphate restriction

T. Knöpfel, A. Odermatt, C. Wagner, 2017, Scientific Reports.

Acute adaptation of renal phosphate transporters in the murine kidney to oral phosphate intake requires multiple signals

C. Wagner, Betul Haykir, A. Daryadel, 2022, Acta physiologica.

Paracellular transport of phosphate along the intestine.

T. Knöpfel, D. Günzel, C. Wagner, 2019, American journal of physiology. Gastrointestinal and liver physiology.

Acute Adaption to Oral or Intravenous Phosphate Requires Parathyroid Hormone.

T. Knöpfel, C. Wagner, J. Biber, 2017, Journal of the American Society of Nephrology.

Adaptation of Opossum Kidney Cells to Luminal Phosphate: Effects of Phosphonoformic Acid and Kinase Inhibitors

C. Wagner, J. Biber, L. Thomas, 2016, Kidney and Blood Pressure Research.

NaPi-IIa interacting proteins and regulation of renal reabsorption of phosphate

N. Déliot, H. Murer, J. Biber, 2010, Urological Research.

Lack of effect of synthetic atrial natriuretic factor on rubidium uptake by human erythrocytes.

J. López-Novoa, A. Fernandez-cruz, C. Caramelo, 1985, Biochemical and biophysical research communications.

GABARAP deficiency modulates expression of NaPi-IIa in renal brush-border membranes.

O. Moe, H. Betz, H. Murer, 2009, American journal of physiology. Renal physiology.

Studies on the topology of the renal type II NaPi-cotransporter

M. Traebert, H. Murer, J. Biber, 1999, Pflügers Archiv.

Expression and regulation of the renal Na/phosphate cotransporter NaPi-IIa in a mouse model deficient for the PDZ protein PDZK1

C. Wagner, B. Kaissling, H. Murer, 2004, Pflügers Archiv.

Molecular mechanisms in proximal tubular and small intestinal phosphate reabsorption (Plenary Lecture)

H. Murer, J. Biber, I. Forster, 2001, Molecular membrane biology.

Characterization of the Osteoclast Vacuolar H+ ATPase: Biochemistry, Subunit Composition and Cloning of Catalytic Subunits

R. Baron, M. Chakraborty, D. Chatterjee, 1994 .

The osteoclast proton pump differs in its pharmacology and catalytic subunits from other vacuolar H(+)-ATPases.

R. Baron, L. Neff, R. Fuchs, 1992, The Journal of experimental biology.

Regulation of the renal type IIa Na/Pi cotransporter by cGMP

H. Völkl, B. Kaissling, M. Traebert, 2001, Pflügers Archiv.

Ifosfamide metabolites CAA, 4-OH-Ifo and Ifo-mustard reduce apical phosphate transport by changing NaPi-IIa in OK cells.

B. Beck-Schimmer, H. Murer, U. Ziegler, 2006, Kidney international.

Effect of extracellular volume expansion on erythrocyte sodium transport in rats.

J. López-Novoa, N. Hernando, R. Bosch, 1990, Archives internationales de physiologie et de biochimie.

Checkpoint kinase Chk2 controls renal Cyp27b1 expression, calcitriol formation, and calcium-phosphate metabolism

A. Hirao, C. Daniel, M. Föller, 2014, Pflügers Archiv - European Journal of Physiology.

Constitutive depletion of Slc34a2/NaPi-IIb in rats causes perinatal mortality

C. Wagner, M. Levi, G. Pellegrini, 2021, Scientific Reports.

Inhibition of sodium/hydrogen exchanger 3 in the gastrointestinal tract by tenapanor reduces paracellular phosphate permeability

J. Caldwell, T. Knöpfel, C. Wagner, 2018, Science Translational Medicine.

Parathyroid hormone-mediated regulation of renal phosphate reabsorption.

H. Völkl, M. Traebert, H. Murer, 2000, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Lack of effect of indomethacin on systemic and splanchnic haemodynamics in portal hypertensive rats.

J. López-Novoa, L. Hernando, N. Hernando, 1985, Clinical science.

Phosphate transporters of the SLC20 and SLC34 families.

H. Murer, J. Biber, I. Forster, 2013, Molecular aspects of medicine.

Phosphate transporters and their function.

J. Biber, I. Forster, N. Hernando, 2013, Annual review of physiology.

cDNA from human ocular ciliary epithelium homologous to βig‐h3 is preferentially expressed as an extracellular protein in the corneal epithelium

J. Crabb, J. Escribano, N. Hernando, 1994, Journal of cellular physiology.

Intestinal Response to Acute Intragastric and Intravenous Administration of Phosphate in Rats.

C. Wagner, M. Levi, E. Layunta, 2019, Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology.

Proximal tubular phosphate reabsorption: molecular mechanisms.

H. Murer, J. Biber, I. Forster, 2000, Physiological reviews.

PDZ-domain interactions and apical expression of type IIa Na/Pi cotransporters

N. Déliot, E. Weinman, E. Lederer, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Nucleotide sequence of a cDNA for the beta 2 subunit isoform of Na+,K(+)-ATPase from human retina.

A. Swaroop, P. Martín-Vasallo, N. Hernando, 1994, Biochimica et biophysica acta.

Phosphate transport kinetics and structure-function relationships of SLC34 and SLC20 proteins.

H. Murer, J. Biber, I. Forster, 2012, Current topics in membranes.

Proximal tubular handling of phosphate: A molecular perspective.

H. Murer, J. Biber, I. Forster, 2006, Kidney international.

Proximal tubular handling of phosphate: A molecular

H. Murer, J. Biber, N. Hernando, 2006 .

Phosphate transporters in renal, gastrointestinal, and other tissues.

A. Werner, I. Forster, V. Sorribas, 2011, Advances in chronic kidney disease.

Phosphate Transport in Epithelial and Nonepithelial Tissue.

K. Gagnon, E. Lederer, N. Hernando, 2020, Physiological reviews.

NaPi-IIa interacting partners and their (un)known functional roles

N. Hernando, 2018, Pflügers Archiv - European Journal of Physiology.

The intestinal phosphate transporter NaPi-IIb (Slc34a2) is required to protect bone during dietary phosphate restriction

T. Knöpfel, A. Odermatt, C. Wagner, 2017, Scientific Reports.

Autosomal-Recessive Mutations in SLC34A1 Encoding Sodium-Phosphate Cotransporter 2A Cause Idiopathic Infantile Hypercalcemia.

M. Konrad, E. Levtchenko, C. Wagner, 2016, Journal of the American Society of Nephrology : JASN.

Expression of NaPi-IIb in rodent and human kidney and upregulation in a model of chronic kidney disease

C. Wagner, Betul Haykir, A. Daryadel, 2020, Pflügers Archiv - European Journal of Physiology.

Mechanisms and Regulation of Intestinal Phosphate Absorption.

C. Wagner, N. Hernando, 2018, Comprehensive Physiology.

Loss of function of NaPiIIa causes nephrocalcinosis and possibly kidney insufficiency

E. Eyal, C. Wagner, E. Holtzman, 2016, Pediatric Nephrology.

The SLC34 family of sodium-dependent phosphate transporters

C. Wagner, J. Biber, I. Forster, 2013, Pflügers Archiv - European Journal of Physiology.

Functional Characterization of Two Naturally Occurring Mutations in the Human Sodium‐Phosphate Cotransporter Type IIa

H. Murer, J. Biber, I. Forster, 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

A dibasic motif involved in parathyroid hormone-induced down-regulation of the type IIa NaPi cotransporter.

H. Murer, J. Biber, N. Hernando, 2000, Proceedings of the National Academy of Sciences of the United States of America.

The presence of the alternatively spliced A2 cassette in the vacuolar H+-ATPase subunit A prevents assembly of the V1 catalytic domain.

P. Kane, R. Baron, W. Horne, 1999, European journal of biochemistry.

Characterization of the osteoclast vacuolar H(+)-ATPase B-subunit.

R. Baron, S. Reddy, G. Roodman, 1995, Gene.

Literature Abstracts

S. Bagnasco, T. Peng, N. Hernando, 2001, Pediatric Nephrology.

Electrophysiological Characterization of the Flounder Type II Na+/Pi Cotransporter (NaPi-5) Expressed in Xenopus laevis Oocytes

F. Lang, C. Wagner, A. Werner, 1997, The Journal of Membrane Biology.

Molecular Determinants of pH Sensitivity of the Type IIa Na/Pi Cotransporter*

H. Murer, J. Biber, I. Forster, 2000, The Journal of Biological Chemistry.

Fibroblast Growth Factor 23 (FGF23) leads to endolysosomal routing of the renal phosphate co-transporters NaPi-IIa and NaPi-IIc in vivo.

C. Wagner, Betul Haykir, N. Hernando, 2021, American journal of physiology. Renal physiology.

Does the composition of urinary extracellular vesicles reflect the abundance of renal Na+/phosphate transporters?

C. Wagner, A. Daryadel, N. Hernando, 2022, Pflügers Archiv - European Journal of Physiology.

Expression of renal and intestinal Na/Pi cotransporters in the absence of GABARAP

H. Betz, H. Murer, A. Liesegang, 2010, Pflügers Archiv - European Journal of Physiology.

Intestinal epithelial ablation of Pit‐2/Slc20a2 in mice leads to sustained elevation of vitamin D3 upon dietary restriction of phosphate

T. Knöpfel, C. Wagner, J. Biber, 2020, Acta physiologica.

Requirement of a leucine residue for (apical) membrane expression of type IIb NaPi cotransporters.

H. Murer, J. Biber, N. Hernando, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Asymmetrical targeting of type II Na-P(i) cotransporters in renal and intestinal epithelial cell lines.

H. Murer, J. Forgo, J. Biber, 2000, American journal of physiology. Renal physiology.

CHAPTER 69 – Proximal Tubular Handling of Phosphate: Na/Pi COTRANSPORTERS AND THEIR REGULATION

H. Murer, J. Biber, I. Forster, 2008 .

Effect of extracellular volume expansion on erythrocyte cation transport in cirrhotic rats

J. López-Novoa, N. Hernando, 1993, Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie.

Checkpoint kinase Chk2 controls renal Cyp27b1 expression, calcitriol formation, and calcium-phosphate metabolism

T. Mak, F. Lang, A. Hirao, 2015, Pflügers Archiv - European Journal of Physiology.

Gene panel sequencing identifies a likely monogenic cause in 7% of 235 Pakistani families with nephrolithiasis

T. Knöpfel, F. Hildebrandt, J. Sayer, 2019, Human Genetics.

Renal Dnase1 expression is regulated by FGF23 but loss of Dnase1 does not alter renal phosphate handling

C. Wagner, Wenhan Chang, Alfred Li, 2021, Scientific Reports.

Na+-dependent phosphate transporters in the murine osteoclast: cellular distribution and protein interactions.

M. Eiden, E. Weinman, M. Chellaiah, 2003, American journal of physiology. Cell physiology.

Expression and regulation of the renal Na/phosphate cotransporter NaPi-IIa in a mouse model deficient for the PDZ protein PDZK1

C. Wagner, B. Kaissling, H. Murer, 2004, Pflügers Archiv.

Expression of multiple Na+,K+‐ATPase genes reveals a gradient of isoforms along the nonpigmented ciliary epithelium: Functional implications in aqueous humor secretion

P. Martín-Vasallo, N. Hernando, M. Coca‐Prados, 1991, Journal of cellular physiology.

Differential expression of the cellular retinaldehyde-binding protein in bovine ciliary epithelium.

J. Crabb, N. Hernando, M. Coca‐Prados, 1993, Experimental Eye Research.