J. Mäki

发表

Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia

I. Miinalainen, J. Myllyharju, A. Rosendahl, 2022, The Journal of biological chemistry.

Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia

I. Miinalainen, J. Myllyharju, A. Rosendahl, 2021, bioRxiv.

Inactivation of the Lysyl Oxidase Gene Lox Leads to Aortic Aneurysms, Cardiovascular Dysfunction, and Perinatal Death in Mice

K. Kivirikko, R. Sormunen, R. Soininen, 2002, Circulation.

Lysyl oxidase is essential for normal development and function of the respiratory system and for the integrity of elastic and collagen fibers in various tissues.

R. Sormunen, J. Myllyharju, R. Soininen, 2005, The American journal of pathology.

Cloning and characterization of a fifth human lysyl oxidase isoenzyme: the third member of the lysyl oxidase-related subfamily with four scavenger receptor cysteine-rich domains.

K. Kivirikko, J. Mäki, H. Tikkanen, 2001, Matrix biology : journal of the International Society for Matrix Biology.

Contribution of HIF-P4H isoenzyme inhibition to metabolism indicates major beneficial effects being conveyed by HIF-P4H-2 antagonism

R. Serpi, E. Dimova, J. Myllyharju, 2022, The Journal of biological chemistry.

Hypoxia-inducible factor prolyl-4-hydroxylase-1 is a convergent point in the reciprocal negative regulation of NF-κB and p53 signaling pathways

U. Bergmann, T. Pihlajaniemi, K. Ullah, 2017, Scientific Reports.

Hypoxia-inducible factor prolyl-4-hydroxylase-1 is a convergent point in the reciprocal negative regulation of NF-κ B and p 53 signaling pathways

Ullah, U. Bergmann, J. Myllyharju, 2017 .

Transmembrane prolyl 4-hydroxylase is a fourth prolyl 4-hydroxylase regulating EPO production and erythropoiesis.

E. Savolainen, K. Kivirikko, J. Myllyharju, 2012, Blood.

Hearts of Hypoxia-inducible Factor Prolyl 4-Hydroxylase-2 Hypomorphic Mice Show Protection against Acute Ischemia-Reperfusion Injury*

I. Hassinen, K. Kivirikko, R. Sormunen, 2010, The Journal of Biological Chemistry.

Expression and Roles of Individual HIF Prolyl 4-Hydroxylase Isoenzymes in the Regulation of the Hypoxia Response Pathway along the Murine Gastrointestinal Epithelium

J. Myllyharju, P. Koivunen, Antti M. Salo, 2021, International journal of molecular sciences.

Lysyl Oxidase (Lox) Gene Deficiency Affects Osteoblastic Phenotype

R. Radlanski, H. Renz, J. Myllyharju, 2009, Calcified Tissue International.

The expression and role of Lysyl oxidase (LOX) in dentinogenesis.

T. Salo, J. Myllyharju, M. Vered, 2013, International endodontic journal.

Interactions between lysyl oxidases and ADAMTS proteins suggest a novel crosstalk between two extracellular matrix families.

J. Myllyharju, S. Apte, D. Hubmacher, 2019, Matrix biology : journal of the International Society for Matrix Biology.

Muscle composition is regulated by a Lox-TGFβ feedback loop

R. Sormunen, J. Myllyharju, Moran Grossman, 2015, Development.

Upregulated integrin α11 in the stroma of cutaneous squamous cell carcinoma promotes skin carcinogenesis

T. Pihlajaniemi, Kris S Kim, Gilbert C Walker, 2022, Frontiers in Oncology.

Identification of suitable reference genes for normalization of reverse transcription quantitative real-time PCR (RT-qPCR) in the fibrotic phase of the bleomycin mouse model of pulmonary fibrosis

T. Pihlajaniemi, J. Koivunen, J. Mäki, 2022, PloS one.

Lysyl oxidases : cloning and characterization of the fourth and the fifth human lysyl oxidase isoenzymes, and the consequences of a targeted inactivation of the first described lysyl oxidase isoenzyme in mice

J. Mäki, 2002 .

Blocking Surgically Induced Lysyl Oxidase Activity Reduces the Risk of Lung Metastases

D. Ribero, Y. Shaked, F. Bertolini, 2017, Cell reports.

The Ras Signaling Inhibitor LOX-PP Interacts with Hsp70 and c-Raf To Reduce Erk Activation and Transformed Phenotype of Breast Cancer Cells

G. Sonenshein, K. Kirsch, J. Myllyharju, 2011, Molecular and Cellular Biology.

Activation of cellular chemotactic responses to chemokines coupled with oxidation of plasma membrane proteins by lysyl oxidase

H. Kagan, H. Lucero, J. Mäki, 2011, Journal of Neural Transmission.

Lysyl Oxidase Oxidizes Cell Membrane Proteins and Enhances the Chemotactic Response of Vascular Smooth Muscle Cells*

K. Ravid, J. Myllyharju, H. Kagan, 2008, Journal of Biological Chemistry.

Cloning and characterization of a fourth human lysyl oxidase isoenzyme.

K. Kivirikko, J. Mäki, 2001, The Biochemical journal.

PHD2 deletion in endothelial or arterial smooth muscle cells reveals vascular cell type-specific responses in pulmonary hypertension and fibrosis

J. Myllyharju, Veli-Pekka Ronkainen, M. Kaakinen, 2022, Angiogenesis.

Lysyl oxidases in mammalian development and certain pathological conditions.

J. Mäki, 2009, Histology and histopathology.

Hypoxia-inducible factor prolyl-4-hydroxylase-1 is a convergent point in the reciprocal negative regulation of NF-κB and p53 signaling pathways

U. Bergmann, T. Pihlajaniemi, K. Ullah, 2017, Scientific Reports.

Prolyl hydroxylase domain 2 reduction enhances skeletal muscle tissue regeneration after soft tissue trauma in mice

J. Myllyharju, J. Fandrey, P. Koivunen, 2020, PloS one.

Contribution of collagen XIII to lung function and development of pulmonary fibrosis

R. Kaarteenaho, J. Koivunen, Antti M. Salo, 2023, BMJ Open Respiratory Research.