J. Barnes

发表

MLL-fusions, here we show that transcriptional-memory from cells-of-origin predicts AML patient survival and allows β-catenin independent transformation in MLL- CSCs-derived from hematopoietic stem cells (HSCs)-enriched LSK population but not myeloid-granulocyte progenitors. Mechanistically, β-caten

Amanda, B. Lenhard, B., 2017 .

The cellular immune response to COVID-19 deciphered by single cell multi-omics across three UK centres

J. Marioni, E. Laurenti, N. Wilson, 2021, medRxiv.

SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes

Masahiro Yoshida, Fabian J. Theis, Oliver Eickelberg, 2020, Nature Medicine.

Local and systemic responses to SARS-CoV-2 infection in children and adults

S. Teichmann, B. Göttgens, R. Lindeboom, 2021, Nature.

SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes

Fabian J Theis, D. Pe’er, A. Regev, 2020, Nature Medicine.

Caffeine inhibits TGFβ activation in epithelial cells, interrupts fibroblast responses to TGFβ, and reduces established fibrosis in ex vivo precision-cut lung slices

G. Jenkins, A. Tatler, R. McAnulty, 2016, Thorax.

Single-cell multi-omics analysis of the immune response in COVID-19

Frances E. Muldoon, Nicola K. Wilson, Kenneth G. C. Smith, 2021, Nature Medicine.

Delta‐Like 4 Activates Notch 3 to Regulate Self‐Renewal in Skeletal Muscle Stem Cells

P. Zammit, J. Beauchamp, Josephine L. Barnes, 2018, Stem cells.

Mapping interindividual dynamics of innate immune response at single-cell resolution

S. Teichmann, J. Marioni, B. Göttgens, 2021, bioRxiv.

Functional crosstalk between Bmi1 and MLL/Hoxa9 axis in establishment of normal hematopoietic and leukemic stem cells.

Amanda J. Wilson, I. Huijbers, E. Taskesen, 2011, Cell stem cell.

Minicircle DNA Provides Enhanced and Prolonged Transgene Expression Following Airway Gene Transfer

S. Hart, A. Tagalakis, M. Munye, 2016, Scientific Reports.

Transcriptional memory from cells-of- origin overrides β -catenin requirement of MLL cancer stem cells

Boris Lenhard, Amanda J. Wilson, Magdalena Zarowiecki, 2017 .

The local and systemic response to SARS-CoV-2 infection in children and adults

S. Teichmann, B. Göttgens, R. Lindeboom, 2021, medRxiv.

Delivery of ENaC siRNA to epithelial cells mediated by a targeted nanocomplex: a therapeutic strategy for cystic fibrosis

S. Hart, A. Tagalakis, A. Weng, 2017, Scientific Reports.

Early human lung immune cell development and its role in epithelial cell fate

J. Marioni, R. Lindeboom, K. Meyer, 2022, bioRxiv.

Epigenetic regulation of cyclooxygenase-2 by methylation of c8orf4 in pulmonary fibrosis

G. Laurent, A. Wells, D. Abraham, 2016, Clinical science.

Effective silencing of ENaC by siRNA delivered with epithelial-targeted nanocomplexes in human cystic fibrosis cells and in mouse lung

D. Baines, S. Hart, A. Tagalakis, 2018, Thorax.

Delta-like 4 on nascent myotubes activates Notch3 to regulate self-renewal in skeletal muscle stem cells

P. Zammit, J. Beauchamp, J. Barnes, 2018 .