Jean Danao

发表

The G-Protein-Coupled Receptor GPR103 Regulates Bone Formation

W. Richards, H. Baribault, H. Tian, 2006, Molecular and Cellular Biology.

Uncompetitive, adduct-forming SARM1 inhibitors are neuroprotective in preclinical models of nerve injury and disease

Sean P. Brown, C. Reynolds, P. R. B. Joseph, 2022, Neuron.

Regulates Bone Formation The G-Protein-Coupled Receptor GPR 103

W. Richards, H. Baribault, H. Tian, 2005 .

Discovery and optimization of a series of liver X receptor antagonists.

Frank Kayser, Peter Coward, Ben Fisher, 2012, Bioorganic & medicinal chemistry letters.

Discovery of a new binding mode for a series of liver X receptor agonists.

Frank Kayser, Peter Coward, Ben Fisher, 2012, Bioorganic & medicinal chemistry letters.

TREM2-activating antibodies abrogate the negative pleiotropic effects of the Alzheimer's disease variant Trem2R47H on murine myeloid cell function

Qingwen Cheng, D. Chui, I. Foltz, 2018, The Journal of Biological Chemistry.

Molecular basis for the loss-of-function effects of the Alzheimer's disease–associated R47H variant of the immune receptor TREM2

A. Lim, Zhongqi Zhang, Zhulun Wang, 2018, The Journal of Biological Chemistry.

Structural and Mechanistic Regulation of the Pro-degenerative NAD Hydrolase SARM1.

Sean P. Brown, D. A. Thayer, X. Bai, 2020, Cell reports.

Genetic Inactivation of Melanin-Concentrating Hormone Receptor Subtype 1 (MCHR1) in Mice Exerts Anxiolytic-Like Behavioral Effects

H. Baribault, H. Tian, Jean Danao, 2006, Neuropsychopharmacology.

G-protein-coupled receptor GPR21 knockout mice display improved glucose tolerance and increased insulin response.

Yang Li, W. Yeh, Yang Li, 2012, Biochemical and biophysical research communications.

Discovery of clinical candidate 1-(4-(3-(4-(1H-benzo[d]imidazole-2-carbonyl)phenoxy)pyrazin-2-yl)piperidin-1-yl)ethanone (AMG 579), a potent, selective, and efficacious inhibitor of phosphodiesterase 10A (PDE10A).

E. Hu, R. Kunz, N. Chen, 2014, Journal of medicinal chemistry.

Discovery of clinical candidate 1-(4-(3-(4-(1H-benzo[d]imidazole-2-carbonyl)phenoxy)pyrazin-2-yl)piperidin-1-yl)ethanone (AMG 579), a potent, selective, and efficacious inhibitor of phosphodiesterase 10A (PDE10A).

E. Hu, R. Kunz, N. Chen, 2014, Journal of medicinal chemistry.