J. A. Fyfe

发表

Metabolic activation of the nucleoside analog 9-[( 2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine in human diploid fibroblasts infected with human cytomegalovirus.

D. Nelson, P. Keller, S. Stanat, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Human immunodeficiency virus integration protein expressed in Escherichia coli possesses selective DNA cleaving activity.

J. A. Fyfe, P. Sherman, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Inhibition of Herpes Simplex Virus-Induced DNA Polymerase Activity and Viral DNA Replication by 9-(2-Hydroxyethoxymethyl) guanine and Its Triphosphate

G. Elion, P. Keller, P. Furman, 1979, Journal of virology.

Human immunodeficiency virus type 1 integration protein: DNA sequence requirements for cleaving and joining reactions

J. A. Fyfe, P. Sherman, M. Dickson, 1992, Journal of virology.

Thymidine kinase from herpes simplex virus phosphorylates the new antiviral compound, 9-(2-hydroxyethoxymethyl)guanine.

R. Miller, G. Elion, P. Keller, 1978, The Journal of biological chemistry.

Activation and antiviral effect of acyclovir in cells infected with a varicella-like simian virus.

K. Soike, G. Elion, C. M. Kelly, 1982, The American journal of medicine.

Clinical isolate of herpes simplex virus type 2 that induces a thymidine kinase with altered substrate specificity

S. Straus, J. Rooney, D. Barry, 1987, Antimicrobial Agents and Chemotherapy.

Mode of action of (R)-9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine against herpesviruses

W. Snowden, W. Alderton, P. Ertl, 1995, Antimicrobial agents and chemotherapy.

Antibacterial activity and mechanism of action of 3'-azido-3'-deoxythymidine (BW A509U)

J. A. Hill, R. Ferone, C. Richards, 1987, Antimicrobial Agents and Chemotherapy.

Kinetic properties and inhibition of orotidine 5'-phosphate decarboxylase. Effects of some allopurinol metabolites on the enzyme.

R. Miller, T. Krenitsky, J. A. Fyfe, 1973, The Journal of biological chemistry.

Inhibition of herpes simplex virus-induced DNA polymerase activity and viral DNA replication by 9-(2-hydroxyethoxymethyl)guanine and its triphosphate

G. Elion, P. Keller, P. Furman, 1979 .

The selectivity of action of an antiherpetic agent, 9‐(2‐hydroxyethoxymethyl) guanine

H. Schaeffer, L. Beauchamp, P. Miranda, 1999, Reviews in medical virology.

3'-Azido-3'-deoxythymidine inhibits the replication of avian leukosis virus

R. Swanstrom, J. Olsen, P. Furman, 1987, Journal of virology.

Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase.

Broder, H. Mitsuya, S. Broder, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl) guanine.

H. Schaeffer, L. Beauchamp, P. Miranda, 1977, Proceedings of the National Academy of Sciences of the United States of America.

An Infrared Study of Monosulfatopentaaquochromium(III) Chloride

K. G. Caulton, R. Anderson, J. A. Fyfe, 1965 .

3-Deazaadenosine 5'-triphosphate: a novel metabolite of 3-deazaadenosine in mouse leukocytes.

P. Keller, J. A. Fyfe, T. Zimmerman, 1989, Biochemical pharmacology.

6-N-substituted derivatives of adenine arabinoside as selective inhibitors of varicella-zoster virus

T. Spector, G. Koszalka, T. Krenitsky, 1991, Antimicrobial Agents and Chemotherapy.

6-Methoxypurine arabinoside as a selective and potent inhibitor of varicella-zoster virus

B. Grace, Fyfe, G. Koszalka, 1991, Antimicrobial Agents and Chemotherapy.

Inhibition by acyclovir of cell growth and DNA synthesis of cells biochemically transformed with herpesvirus genetic information.

G. Elion, P. Keller, P. Furman, 1980, Virology.

A human cytomegalovirus mutant resistant to the nucleoside analog 9-([2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine (BW B759U) induces reduced levels of BW B759U triphosphate.

D. Coen, S. Stanat, K. Biron, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Mutant varicella-zoster virus thymidine kinase: correlation of clinical resistance and enzyme impairment

S. Short, R. Gaillard, J. A. Fyfe, 1991, Journal of virology.

Differential phosphorylation of (E)-5-(2-bromovinyl)-2'-deoxyuridine monophosphate by thymidylate kinases from herpes simplex viruses types 1 and 2 and varicella zoster virus.

J. A. Fyfe, 1982, Molecular pharmacology.

Levels of nucleoside and nucleotide kinases in rhesus monkey tissues.

R. Miller, T. Krenitsky, J. A. Fyfe, 1974, Biochemical pharmacology.

Xanthine phosphoribosyltransferase from Streptococcus faecalis. Properties and specificity.

R. Miller, G. Elion, J. A. Fyfe, 1974, Archives of biochemistry and biophysics.

The anti-hepatitis B virus activities, cytotoxicities, and anabolic profiles of the (-) and (+) enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine

L W Frick, R. Schinazi, D. Liotta, 1992, Antimicrobial Agents and Chemotherapy.

Cytoplasmic 5'-nucleotidase catalyzes acyclovir phosphorylation.

P. Keller, J. A. Fyfe, S. A. McKee, 1985, The Journal of biological chemistry.

Enzymatic phosphorylation of acyclic nucleoside analogs and correlations with antiherpetic activities.

H. Schaeffer, L. Beauchamp, G. Elion, 1981, Biochemical pharmacology.

Varicella-zoster virus thymidine kinase. Characterization and substrate specificity.

M. Almond, G. Koszalka, T. Krenitsky, 1993, Biochemical pharmacology.

Antibacterial Activity and Mechanism of Action of 3 '-Azido-3 '-Deoxythymidine ( BW A 509 U )

R. Ferone, P. Lynn, G. A. Freeman, 2022 .

Altered thymidine-thymidylate kinases from strains of herpes simplex virus with modified drug sensitivities to acyclovir and (E)-5-(2-bromovinyl)-2'-deoxyuridine.

P. Keller, J. A. Fyfe, S. A. McKee, 1983, Molecular pharmacology.

Modifications on the heterocyclic base of acyclovir: syntheses and antiviral properties.

D. J. Bauer, B. Dolmatch, H. Schaeffer, 1985, Journal of medicinal chemistry.

Nucleotide sequence changes in thymidine kinase gene of herpes simplex virus type 2 clones from an isolate of a patient treated with acyclovir

H. Otsuka, S. Kit, M. Sheppard, 1987, Antimicrobial Agents and Chemotherapy.

Ribavirin antagonizes the effect of azidothymidine on HIV replication

R. Schooley, M. Hirsch, C. Crumpacker, 1987, Science.

Clinical Isolate ofHerpesSimplex Virus Type2ThatInduces a Thymidine KinasewithAlteredSubstrate Specificity

S. Straus, J. Rooney, D. Barry, 1987 .

Enzymatic assay for deoxyribonucleoside triphosphates using synthetic oligonucleotides as template primers.

J. A. Fyfe, P. Sherman, 1989, Analytical biochemistry.

Selection and preliminary characterization of acyclovir-resistant mutants of varicella zoster virus.

G. Elion, K. Biron, J. A. Fyfe, 1982, The American journal of medicine.

Vitamin B12 Biosynthesis ENZYME STUDIES ON THE FORMATION OF THE α-GLYCOSIDIC NUCLEOTIDE PRECURSOR

H. Friedmann, J. A. Fyfe, 1969 .

DNA Cleaving Activity of Purified Human Immunodeficiency Virus Integration Protein

J. A. Fyfe, P. Sherman, 1991 .

KP544 amplifies the effects of nerve growth factor on cell differentiation and is neuroprotective

T. Yamaji, L. Beauchamp, N. Matsuoka, 2004 .

[125] Nicotinate ribonucleotide: Benzimidazole (adenine) phosphoribosyltransferase (nicotinatenucleotide: Dimethylbenzimidazole phosphoribosyltransferase, EC 2.4.2.21)

H. Friedmann, J. A. Fyfe, 1971 .

Cobalamin inhibition of HIV-1 integrase and integration of HIV-1 DNA into cellular DNA.

D. Shugars, D. Sauls, J. Weinberg, 1998, Biochemical and biophysical research communications.

Pseudovitamin B 12 biosynthesis. Enzymatic formation of a new adenylic acid, 7-alpha-D-ribofuranosyladenine 5'-phosphate.

H. Friedmann, J. A. Fyfe, 1969, The Journal of biological chemistry.

Selectivity of antiviral effectiveness derived from differences of herpes simplex virus-coded thymidine kinases.

J. A. Fyfe, 1984, Advances in experimental medicine and biology.

GMP synthetase from Escherichia coli B-96. Interactions with substrate analogs.

R. Miller, T. Spector, T. Krenitsky, 1974, Biochimica et biophysica acta.

Modifications on the heterocyclic base of acyclovir: syntheses and antiviral properties.

D. J. Bauer, B. Dolmatch, H. Schaeffer, 1985, Journal of medicinal chemistry.