Yunjiao He

Crystallographic Snapshots of Class A β-Lactamase Catalysis Reveal Structural Changes That Facilitate β-Lactam Hydrolysis*

Xuhui Huang, Yanxiang Zhao, Jinping Lei, 2017, The Journal of Biological Chemistry.

Modified Penicillin Molecule with Carbapenem-Like Stereochemistry Specifically Inhibits Class C β-Lactamases

Tianfeng Chen, Yanxiang Zhao, Kin-Fai Chan, 2017, Antimicrobial Agents and Chemotherapy.

Perspectives on miRNAs Targeting DKK1 for Developing Hair Regeneration Therapy

Deependra Tyagi, Yunjiao He, N. Rcheulishvili, 2021, Cells.

Disruption of SND1–MTDH Interaction by a High Affinity Peptide Results in SND1 Degradation and Cytotoxicity to Breast Cancer Cells In Vitro and In Vivo

L. Chow, T. Chen, K. Choy, 2020, Molecular Cancer Therapeutics.

Vacuolin-1 inhibits endosomal trafficking and metastasis via CapZβ

J. Yue, W. Cho, Mengsu Yang, 2021, Oncogene.

Targeting the potent Beclin 1–UVRAG coiled-coil interaction with designed peptides enhances autophagy and endolysosomal trafficking

Renxiao Wang, Yanxiang Zhao, Z. Yue, 2018, Proceedings of the National Academy of Sciences.

The hydrolytic water molecule of Class A β-lactamase relies on the acyl-enzyme intermediate ES* for proper coordination and catalysis

Xuhui Huang, Yanxiang Zhao, Jinping Lei, 2020, Scientific Reports.

Perturbing the general base residue Glu166 in the active site of class A β-lactamase leads to enhanced carbapenem binding and acylation.

Yanxiang Zhao, Yongwen Jiang, Xuehua Pan, 2014, Biochemistry.