J. Tomberg

发表

Overexpression and enzymatic characterization of Neisseria gonorrhoeae penicillin-binding protein 4.

C. Davies, R. Nicholas, W. Gutheil, 2003, European journal of biochemistry.

Crystal structures of covalent complexes of β-lactam antibiotics with Escherichia coli penicillin-binding protein 5: toward an understanding of antibiotic specificity.

G. Nicola, R. Pratt, C. Davies, 2010, Biochemistry.

In Vivo-Selected Compensatory Mutations Restore the Fitness Cost of Mosaic penA Alleles That Confer Ceftriaxone Resistance in Neisseria gonorrhoeae

M. Unemo, Julie C. Dunning Hotopp, R. Nicholas, 2018, mBio.

A highly conserved interaction involving the middle residue of the SXN active-site motif is crucial for function of class B penicillin-binding proteins: mutational and computational analysis of PBP 2 from N. gonorrhoeae.

C. Davies, R. Nicholas, B. Temple, 2012, Biochemistry.

Molecular and structural analysis of mosaic variants of penicillin-binding protein 2 conferring decreased susceptibility to expanded-spectrum cephalosporins in Neisseria gonorrhoeae: role of epistatic mutations.

Magnus Unemo, Christopher Davies, M. Unemo, 2010, Biochemistry.

Identification of Amino Acids Conferring High-Level Resistance to Expanded-Spectrum Cephalosporins in the penA Gene from Neisseria gonorrhoeae Strain H041

Magnus Unemo, Christopher Davies, M. Unemo, 2013, Antimicrobial Agents and Chemotherapy.

Genetics of Chromosomally Mediated Intermediate Resistance to Ceftriaxone and Cefixime in Neisseria gonorrhoeae

Magnus Unemo, Christopher Davies, M. Unemo, 2009, Antimicrobial Agents and Chemotherapy.

Recognition of the β-lactam carboxylate triggers acylation of Neisseria gonorrhoeae penicillin-binding protein 2

Ashutosh Kumar Singh, C. Davies, R. Nicholas, 2019, The Journal of Biological Chemistry.

Alanine 501 Mutations in Penicillin-Binding Protein 2 from Neisseria gonorrhoeae: Structure, Mechanism, and Effects on Cephalosporin Resistance and Biological Fitness.

M. Unemo, C. Davies, R. Nicholas, 2017, Biochemistry.

Properly folded and functional PorB from Neisseria gonorrhoeae inhibits dendritic cell stimulation of CD4+ T cell proliferation

K. McKinnon, R. Nicholas, G. Sempowski, 2018, The Journal of Biological Chemistry.

Crystal Structures of Penicillin-binding Protein 2 from Penicillin-susceptible and -resistant Strains of Neisseria gonorrhoeae Reveal an Unexpectedly Subtle Mechanism for Antibiotic Resistance*

Ashley M Deacon, Christopher Davies, A. Deacon, 2009, Journal of Biological Chemistry.

Diffusion of Antibiotics through the PilQ Secretin in Neisseria gonorrhoeae Occurs through the Immature, Sodium Dodecyl Sulfate-Labile Form

R. Nicholas, S. Nandi, J. Tomberg, 2015, Journal of bacteriology.

Genetics of Chromosomally Mediated Intermediate Resistance to Ceftriaxone and Ceﬁxime in Neisseria gonorrhoeae (cid:1)

M. Unemo, M. Duncan, C. Davies, 2009 .

Crystal Structure of Wild-type Penicillin-Binding Protein 5 from Escherichia coli : Implications for Deacylation of the Acyl-Enzyme Complex

G. Nicola, R. Nicholas, J. Tomberg, 2003 .

Structure of the N-terminal domain of human CEACAM1: binding target of the opacity proteins during invasion of Neisseria meningitidis and N. gonorrhoeae.

Christopher Davies, C. Davies, R. Nicholas, 2006, Acta crystallographica. Section D, Biological crystallography.

Mutational analysis of LtgC, a lytic transglycosylase required for cell separation in Neisseria gonorrhoeae

R. Nicholas, J. P. Dillard, R. Schaub, 2023, bioRxiv.

Neisseria gonorrhoeae penicillin-binding protein 3 exhibits exceptionally high carboxypeptidase and beta-lactam binding activities.

R. Nicholas, J. Höltje, W. Gutheil, 2003, Biochemistry.

Structural Effect of the Asp345a Insertion in Penicillin-Binding Protein 2 from Penicillin-Resistant Strains of Neisseria gonorrhoeae

C. Davies, R. Nicholas, J. Tomberg, 2014, Biochemistry.

Commensal Neisseria species share immune suppressive mechanisms with Neisseria gonorrhoeae

R. Nicholas, J. Duncan, J. Tomberg, 2022, bioRxiv.

Mutations in penicillin-binding protein 2 from cephalosporin-resistant Neisseria gonorrhoeae hinder ceftriaxone acylation by restricting protein dynamics

Ashutosh Kumar Singh, M. Unemo, C. Davies, 2020, The Journal of Biological Chemistry.

Mutations in PBP2 from ceftriaxone-resistant Neisseria gonorrhoeae alter the dynamics of the β3–β4 loop to favor a low-affinity drug-binding state

C. Davies, R. Nicholas, Carly A. Sciandra, 2021, The Journal of biological chemistry.

Crystal Structure of Wild-type Penicillin-binding Protein 5 from Escherichia coli

G. Nicola, C. Davies, R. Nicholas, 2003, Journal of Biological Chemistry.

Crystal structures of covalent complexes of β -lactam antibiotics with E. coli penicillin-binding protein 5: toward an understanding of antibiotic specificity

G. Nicola, Christopher, R. Pratt, 2011 .

Molecular and structural analysis of mosaic variants of penicillin-binding protein 2 conferring decreased susceptibility to expanded-spectrum cephalosporins in Neisseria gonorrhoeae: role of epistatic mutations.

M. Unemo, C. Davies, R. Nicholas, 2010, Biochemistry.