August John

Patient-specific multi-omics models and the application in personalized combination therapy.

Krishna R. Kalari, K. Kalari, Liewei Wang, 2020, Future oncology.

TRAF4 hyperactivates HER2 signaling and contributes to Trastuzumab resistance in HER2-positive breast cancer

R. Weinshilboum, Liewei Wang, Jia Yu, 2022, Oncogene.

3D CRISPR screen in prostate cancer cells reveals PARP inhibitor sensitization through TBL1XR1-SMC3 interaction

R. Weinshilboum, Liewei Wang, Lixuan Wei, 2022, Frontiers in Oncology.

Pharmacotypes across the genomic landscape of pediatric acute lymphoblastic leukemia and impact on treatment response

G. Rosner, M. Relling, C. Pui, 2022, Nature medicine.

Resistance to venetoclax and hypomethylating agents in acute myeloid leukemia

S. Kaufmann, August John, Antoine N. Saliba, 2020, Cancer drug resistance.

Network-based systems pharmacology reveals heterogeneity in LCK and BCL2 signaling and therapeutic sensitivity of T-cell acute lymphoblastic leukemia

M. Relling, C. Pui, W. Evans, 2021, Nature Cancer.