G. Preston

发表

Altered mRNA expression in renal biopsy tissue from patients with IgA nephropathy.

Hong-Wei Sun, D. Alcorta, R. Falk, 2003, Kidney international.

Proteinase 3 sidesteps caspases and cleaves p21(Waf1/Cip1/Sdi1) to induce endothelial cell apoptosis.

L. Hengst, R. Falk, J. Jennette, 2004, Kidney international.

Anti-LAMP-2 antibodies are not prevalent in patients with antineutrophil cytoplasmic autoantibody glomerulonephritis.

D. O'Dell, Yichun Hu, D. Bunch, 2012, Journal of the American Society of Nephrology : JASN.

DRB1*15 allele is a risk factor for PR3-ANCA disease in African Americans.

F. Arnett, Yichun Hu, D. Bunch, 2011, Journal of the American Society of Nephrology : JASN.

Regulation of apoptosis by low serum in cells of different stages of neoplastic progression: enhanced susceptibility after loss of a senescence gene and decreased susceptibility after loss of a tumor suppressor gene.

J. Barrett, R. Maronpot, G. Preston, 1994, Cancer research.

Circumvention of normal constraints on granule protein gene expression in peripheral blood neutrophils and monocytes of patients with antineutrophil cytoplasmic autoantibody-associated glomerulonephritis.

D. Alcorta, R. Falk, J. Jennette, 2004, Journal of the American Society of Nephrology : JASN.

Effects of alterations in calcium homeostasis on apoptosis during neoplastic progression.

J. Barrett, E. Murphy, J. Biermann, 1997, Cancer research.

ANCA-associated Vasculitis Patients Have Defective Treg Function Exacerbated by Presence of a Suppression-Resistant Effector Population

D. Bunch, J. Jennette, S. Hogan, 2013 .

Patients with antineutrophil cytoplasmic antibody-associated vasculitis have defective Treg cell function exacerbated by the presence of a suppression-resistant effector cell population.

Yichun Hu, D. Bunch, R. Falk, 2013, Arthritis and rheumatism.

Novel effects of neutrophil-derived proteinase 3 and elastase on the vascular endothelium involve in vivo cleavage of NF-kappaB and proapoptotic changes in JNK, ERK, and p38 MAPK signaling pathways.

R. Falk, J. Jennette, W. Pendergraft, 2002, Journal of the American Society of Nephrology : JASN.

Understanding the pathogenesis of ANCA: where are we today?

R. Falk, Hong Xiao, G. Preston, 2002, Cleveland Clinic journal of medicine.

ANCA patients have T cells responsive to complementary PR-3 antigen.

R. Tisch, R. Falk, J. Jennette, 2008, Kidney international.

Serum Matrix Metalloproteinases MMP-2 and MMP-3 Levels in Dialysis Patients Vary Independently of CRP and IL-6 Levels

D. Alcorta, R. Falk, J. Jennette, 2002, Nephron.

ANCA antigens, proteinase 3 and myeloperoxidase, are not expressed in endothelial cells.

D. Alcorta, R. Falk, J. Jennette, 2000, Kidney international.

Apoptosis and altered redox state induced by caffeic acid phenethyl ester (CAPE) in transformed rat fibroblast cells.

J. Barrett, G. Solomon, A. Carothers, 1995, Cancer research.

Autoantigen complementarity and its contributions to hallmarks of autoimmune disease.

W. Pendergraft, G. Preston, A. Badhwar, 2015, Journal of theoretical biology.

Autoimmunity to the alpha 3 chain of type IV collagen in glomerulonephritis is triggered by 'autoantigen complementarity'.

C. Pusey, D. Bunch, H. Cook, 2015, Journal of autoimmunity.

Autoimmunity: Does autoantigen complementarity underlie PR3-ANCA AAV?

R. Falk, G. Preston, 2011, Nature Reviews Rheumatology.

Longitudinal studies of patients with ANCA vasculitis demonstrate concurrent reactivity to complementary PR3 protein segments cPR3m and cPR3C and with no reactivity to cPR3N

R. Falk, J. Charles Jennette, P. Hewins, 2011, Autoimmunity.

Antibodies with dual reactivity to plasminogen and complementary PR3 in PR3-ANCA vasculitis.

A. Wolberg, R. Falk, J. Jennette, 2008, Journal of the American Society of Nephrology : JASN.

Autoimmunity is triggered by cPR-3(105–201), a protein complementary to human autoantigen proteinase-3

A. Tropsha, C. Carter, Ruchir R. Shah, 2004, Nature Medicine.

Internalization of proteinase 3 is concomitant with endothelial cell apoptosis and internalization of myeloperoxidase with generation of intracellular oxidants.

P. Heeringa, R. Falk, J. Jennette, 2001, The American journal of pathology.

Kidney Disease: Goodpasture's Disease, Lupus Nephritis, ANCA-Associated Glomerulonephritis

R. Falk, G. Preston, B. Pressler, 2006 .

Isolation and Characterization of a 1-ÃŸ-D-Arabinofuranosylcytosine-resistant Chinese Hamster Ovary Cell Mutant That Is Also X-Ray Sensitive and Is Noncomplementary with Ataxia Telangiectasia Cells1

R. J. Preston, G. Preston, H. S. Payne, 2006 .

Isolation and characterization of a 1-beta-D-arabinofuranosylcytosine-resistant Chinese hamster ovary cell mutant that is also X-ray sensitive and is noncomplementary with ataxia telangiectasia cells.

R. J. Preston, G. Preston, H. S. Payne, 1992, Cancer research.

Induction of apoptosis by c-Fos protein

J. Barrett, Y. Yin, D. Alcorta, 1996, Molecular and cellular biology.

Apoptotic response to growth factor deprivation involves cooperative interactions between c-Fos and p300

J. Barrett, D. Srinivasan, G. Preston, 2000, Cell Death and Differentiation.

Epigenetic basis for aberrant upregulation of autoantigen genes in humans with ANCA vasculitis.

T. Magnuson, D. Ciavatta, R. Falk, 2010, The Journal of clinical investigation.

Expression profile of leukocyte genes activated by anti-neutrophil cytoplasmic autoantibodies (ANCA).

D. Alcorta, R. Falk, J. Jennette, 2002, Kidney international.

Autoimmune Disease in the Kidney

R. Falk, G. Preston, 2014 .

Epitope specificity determines pathogenicity and detectability in ANCA-associated vasculitis.

P. Heeringa, S. Holdsworth, Yichun Hu, 2013, The Journal of clinical investigation.

Autoantigen complementarity: a new theory implicating complementary proteins as initiators of autoimmune disease

R. Falk, J. Jennette, W. Pendergraft, 2004, Journal of Molecular Medicine.

High Basal Activity of the PTPN22 Gain-of-Function Variant Blunts Leukocyte Responsiveness Negatively Affecting IL-10 Production in ANCA Vasculitis

Yichun Hu, Yali Cao, R. Falk, 2012, PloS one.

A study of conformational restraints on reactivity of human PR3-specific autoantibodies (ANCA) facilitated through protein folding manipulations of a new recombinant proteinase 3 protein

Lila Farrag, R. Falk, J. Jennette, 2007, Autoimmunity.

ANCA signaling: not just a matter of respiratory burst.

R. Falk, G. Preston, 2001, Kidney international.

New insights that link microbes with the generation of antineutrophil cytoplasmic autoantibodies: the theory of autoantigen complementarity

R. Falk, W. Pendergraft, G. Preston, 2005, Current opinion in nephrology and hypertension.

Myeloperoxidase interacts with endothelial cell-surface cytokeratin 1 and modulates bradykinin production by the plasma Kallikrein-Kinin system.

A. Schmaier, J. Astern, R. Falk, 2007, The American journal of pathology.

Dysregulation of autoantigen genes in ANCA-associated vasculitis involves alternative transcripts and new protein synthesis.

D. Ciavatta, R. Falk, J. Jennette, 2015, Journal of the American Society of Nephrology : JASN.

Microarray Studies of Gene Expression in Circulating Leukocytes in Kidney Diseases

D. Alcorta, R. Falk, J. Jennette, 2002, Nephron Experimental Nephrology.

Gene expression profiles of circulating leukocytes correlate with renal disease activity in IgA nephropathy.

D. Alcorta, R. Falk, J. Jennette, 2004, Kidney international.

Expression of p300-truncated fragments results in the modulation of apoptosis in rat mesangial cells.

R. Falk, M. Segelmark, W. Pendergraft, 2000, Kidney international.

ANCA patients have T cells responsive to complementary PR-3 antigen.

J. Jennette, S. Hogan, H. Chin, 2008, Kidney international.

Cellular senescence and cancer.

J. Barrett, P. Vojta, D. Alcorta, 1994, Cold Spring Harbor symposia on quantitative biology.

Anti-LAMP-2 antibodies are not prevalent in patients with antineutrophil cytoplasmic autoantibody glomerulonephritis.

Yichun Hu, D. Bunch, J. Jennette, 2012, Journal of the American Society of Nephrology : JASN.