M. Sannigrahi

发表

I. Novel HCV NS5B polymerase inhibitors: discovery of indole 2-carboxylic acids with C3-heterocycles.

B. Feld, R. Palermo, J. Duca, 2011, Bioorganic & medicinal chemistry letters.

Structure-activity relationship (SAR) development and discovery of potent indole-based inhibitors of the hepatitis C virus (HCV) NS5B polymerase.

B. Feld, J. Duca, F. G. Njoroge, 2012, Journal of medicinal chemistry.

P4 capped amides and lactams as HCV NS3 protease inhibitors with improved potency and DMPK profile.

X. Tong, A. Prongay, V. Girijavallabhan, 2010, Bioorganic & medicinal chemistry letters.

Cyclic sulfones as novel P3-caps for hepatitis C virus NS3/4A (HCV NS3/4A) protease inhibitors: synthesis and evaluation of inhibitors with improved potency and pharmacokinetic profiles.

X. Tong, A. McPhail, A. Arasappan, 2010, Journal of medicinal chemistry.

Stereocontrolled synthesis of spirocyclics

M. Sannigrahi, 1999 .

Stereoselective Synthesis of β-Substituted β-Amino Sulfones and Sulfonamides via Addition of Sulfonyl Anions to Chiral N-Sulfinyl Imines

A. McPhail, A. Arasappan, T. Chan, 2006 .

Discovery of an irreversible HCV NS5B polymerase inhibitor.

J. Gesell, J. Duca, F. G. Njoroge, 2013, Bioorganic & medicinal chemistry letters.

The introduction of P4 substituted 1-methylcyclohexyl groups into Boceprevir: a change in direction in the search for a second generation HCV NS3 protease inhibitor.

Zhuyan Guo, Frank Bennett, X. Tong, 2010, Bioorganic & medicinal chemistry letters.

Carboxy mediated stereoselective reduction of ketones with sodium triacetoxyborohydride: synthesis of novel 3,4-fused tetrahydropyran and tetrahydrofuran prolines☆

V. Girijavallabhan, A. Saksena, M. Sannigrahi, 2004 .

Rapid assembly of tetrahydrodibenzofurans and tetrahydrocarbazoles from benzene and o-iodophenols and o-iodoanilines: reductive radical arylation of benzene in action

D. Crich, M. Sannigrahi, 2002 .

Novel synthesis of sterically hindered N-substituted lactams from imides

F. G. Njoroge, T. Chan, N. Shih, 2006 .

Applications of 5-Endo-trigonal Cyclization: Construction of Compounds Relevant to the Synthesis of Prostaglandins and Methyl epi-Jasmonate.

D. Clive, M. Sannigrahi, D. Mayhew, 1999, The Journal of organic chemistry.

Syntheses of dipeptides containing (1R,5S)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2(S)-carboxylic acid (4), (1R,5S)-spiro[3-azabicyclo[3.1.0]hexane-6,1′-cyclopropane]- 2(S)-carboxylic acid (5) and (1S,5R)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2(S)-carboxylic acid (6)

A. McPhail, T. Chan, Yuhua Huang, 2006 .

Discovery of Narlaprevir (SCH 900518): A Potent, Second Generation HCV NS3 Serine Protease Inhibitor.

Weiying Yang, Frank Bennett, Jesse Wong, 2010, ACS medicinal chemistry letters.

A facile and efficient synthesis of 3,3-dimethyl isopropylidene proline from (+)-3-carene.

V. Girijavallabhan, A. Saksena, M. Sannigrahi, 2010, The Journal of organic chemistry.

Toward second generation hepatitis C virus NS3 serine protease inhibitors: discovery of novel P4 modified analogues with improved potency and pharmacokinetic profile.

Frank Bennett, X. Tong, A. Arasappan, 2009, Journal of medicinal chemistry.

Direct measurement of enol ether radical cation reaction kinetics.

M. Newcomb, D. Crich, M. Sannigrahi, 2001, Journal of the American Chemical Society.

Design, synthesis, and evaluation of oxygen-containing macrocyclic peptidomimetics as inhibitors of HCV NS3 protease.

X. Tong, Melissa L. Blackman, J. Pichardo, 2009, Journal of medicinal chemistry.

Stereoselective Synthesis of β‐Substituted β‐Amino Sulfones and Sulfonamides via Addition of Sulfonyl Anions to Chiral N‐Sulfinyl Imines.

A. McPhail, A. Arasappan, T. Chan, 2006 .

Stereoselective synthesis of beta-substituted beta-amino sulfones and sulfonamides via addition of sulfonyl anions to chiral N-sulfinyl imines.

A. McPhail, A. Arasappan, T. Chan, 2006, Organic letters.