M. Zrada

发表

A potent and orally active HIV-1 integrase inhibitor.

Wei Xu, D. Hazuda, Michael D. Miller, 2007, Bioorganic & medicinal chemistry letters.

Differences in the absorption, metabolism and biliary excretion of a diastereomeric pair of α v β 3 - antagonists in rat: limited role of P-glycoprotein

B. Ma, J. Hochman, C. Tang, 2002, Xenobiotica; the fate of foreign compounds in biological systems.

Kinesin spindle protein (KSP) inhibitors. Part V: discovery of 2-propylamino-2,4-diaryl-2,5-dihydropyrroles as potent, water-soluble KSP inhibitors, and modulation of their basicity by beta-fluorination to overcome cellular efflux by P-glycoprotein.

P. Coleman, Christopher D. Cox, Weikang Tao, 2007, Bioorganic & medicinal chemistry letters.

MK-8825: a potent and selective CGRP receptor antagonist with good oral activity in rats.

J. Vacca, H. Selnick, S. Graham, 2012, Bioorganic & medicinal chemistry letters.

Synthesis and hypoglycemic activity of substituted 8-(1-piperazinyl)imidazo[1,2-a]pyrazines.

M. Maccoss, R. Tolman, R Saperstein, 1992, Journal of medicinal chemistry.

9-hydroxyazafluorenes and their use in thrombin inhibitors.

Youwei Yan, B. Wong, P. Nantermet, 2005, Journal of medicinal chemistry.

Development of an efficient and selective radioligand for bradykinin B1 receptor occupancy studies.

M. Bock, R. Freidinger, R. Chang, 2004, Bioorganic & Medicinal Chemistry Letters.

Discovery of 1,4-substituted piperidines as potent and selective inhibitors of T-type calcium channels.

Steven V. Fox, S. Doran, W. Shipe, 2008, Journal of medicinal chemistry.

Selectivity of (+)-4-propyl-9-hydroxynaphthoxazine [(+)-PHNO] for dopamine receptors in vitro and in vivo.

V. J. Lotti, D. Taylor, M. Williams, 1985, The Journal of pharmacology and experimental therapeutics.

Design, synthesis, and evaluation of a novel 4-aminomethyl-4-fluoropiperidine as a T-type Ca2+ channel antagonist.

Steven V. Fox, S. Doran, W. Shipe, 2008, Journal of medicinal chemistry.

Understanding and reducing the experimental variability of in vitro plasma protein binding measurements.

Bernard K. Choi, L. Cohen, Paul J. Harradine, 2014, Journal of pharmaceutical sciences.

Structure-affinity relationships of arylquinolizines at alpha-adrenoceptors.

J. Huff, J. Vacca, W. Randall, 1988, Journal of medicinal chemistry.

The anesthetized guinea pig: an effective early cardiovascular derisking and lead optimization model.

M. Nishida, K. Hoagland, J. Imredy, 2013, Journal of pharmacological and toxicological methods.

8-Hydroxy-3,4-dihydropyrrolo[1,2-a]pyrazine-1(2H)-one HIV-1 integrase inhibitors.

D. Hazuda, W. Schleif, L. Gabryelski, 2007, Bioorganic & medicinal chemistry letters.