K. Kawai

发表

Intestinal absorption and excretion of troglitazone sulphate, a major biliary metabolite of troglitazone

S. Muramatsu, T. Hirota, K. Kawai, 2000, Xenobiotica; the fate of foreign compounds in biological systems.

OATP1B1, OATP1B3, AND MRP2 ARE INVOLVED IN HEPATOBILIARY TRANSPORT OF OLMESARTAN, A NOVEL ANGIOTENSIN II BLOCKER

T. Abe, D. Nakai, Y. Yoshigae, 2006, Drug Metabolism and Disposition.

Disposition and metabolism of the new oral antidiabetic drug troglitazone in rats, mice and dogs.

T. Kinoshita, H. Iwabuchi, K. Nakamura, 1997, Arzneimittel-Forschung.

Disposition and metabolism of pravastatin sodium in rats, dogs and monkeys

T. Tokui, M. Tanaka, K. Kawai, 1992, European Journal of Drug Metabolism and Pharmacokinetics.

Absorption, distribution and excretion of the new thienopyridine agent prasugrel in rats

N. Farid, A. Kurihara, K. Hagihara, 2007, Xenobiotica; the fate of foreign compounds in biological systems.

A novel radioiodination reagent for protein radiopharmaceuticals with L-lysine as a plasma-stable metabolizable linkage to liberate m-iodohippuric acid after lysosomal proteolysis.

H. Saji, M. Ono, Y. Arano, 1997, Journal of medicinal chemistry.

Stereospecific synthesis of a family of novel (E)‐2‐aryl‐1‐silylalka‐1,4‐dienes or (E)‐4‐aryl‐5‐silylpenta‐1,2,4‐trienes via a cross‐coupling of (Z)‐silyl(stannyl)ethenes with allyl halides or propargyl bromide

K. Kawai, Fumio Sasaki, T. Nakano,, 2008 .

COVALENT BINDING OF RADIOACTIVITY FROM [14C]ROFECOXIB, BUT NOT [14C]CELECOXIB OR [14C]CS-706, TO THE ARTERIAL ELASTIN OF RATS

S. Inoue, T. Hirota, K. Koyama, 2006, Drug Metabolism and Disposition.

Running Title : Covalent binding of rofecoxib to arterial elastin Corresponding

S. Inoue, T. Hirota, K. Koyama, 2006 .

SPECIES DIFFERENCE IN THE METABOLISM OF L-5-HYDROXY-TRYPTOPHAN AND 5-HYDROXYTRYPTAMINE IN MICE, RATS, DOGS, AND MONKEYS

H. Shindo, K. Kawai, T. Maeda, 1979 .

OATP 1 B 1 , OATP 1 B 3 , AND MRP 2 ARE INVOLVED IN HEPATOBILIARY TRANSPORT OF OLMESARTAN , A NOVEL ANGIOTENSIN II BLOCKER

T. Abe, D. Nakai, Y. Yoshigae, 2006 .

Tumor Selective Effect of RS-1541 (Palmitoyl-Rhizoxin) in M5076 Sarcoma and Host Tissues in Vivo

Takashi Inoue, K. Sasagawa, T. Tokui, 1995, Pharmaceutical Research.

Pharmacokinetics and Disposition of CS-023 (RO4908463), a Novel Parenteral Carbapenem, in Animals

T. Hirota, S. Kuwahara, T. Shibayama, 2006, Antimicrobial Agents and Chemotherapy.

Disposition and Metabolism of the Oral Antidiabetic Drug Troglitazone in Monkeys

H. Haruyama, H. Ikenaga, M. Ishikawa, 2000 .

Urinary metabolites of 1-(3-Mercapto-2-D-methyl-1-oxopropyl)-L-proline(SQ-14225),a new antihypertensive agent, in rats and dogs.

H. Shindo, K. Kawai, T. Ikeda, 1981 .

Contribution of serum lipoproteins as carriers of antitumour agent RS‐1541 (palmitoyl rhizoxin) in mice

T. Kobayashi, K. Sasagawa, T. Tokui, 1994, Biopharmaceutics & drug disposition.

Absorption, distribution, excretion and metabolism of cefmetazole in cynomolgus monkeys.

S. Sugawara, H. Shindo, K. Kawai, 1982, Journal of antibiotics (Tokyo. 1968).

Short communication: An alternative and effective catalyst in the stereo‐specific reaction of Z‐1‐aryl‐1‐stannyl‐2‐silylethenes with allyl bromide

T. Miyamoto, K. Kawai, T. Nakano,, 2005 .

In vitro studies on the metabolic pathway of SQ 14225 (Captopril) and mechanism of mixed disulfide formation.

H. Shindo, K. Kawai, T. Ikeda, 1981, Journal of pharmacobio-dynamics.

Distribution of KAI-9803, a Novel δ-Protein Kinase C Inhibitor, after Intravenous Administration to Rats

A. Kurihara, Y. Miyaji, Leon Chen, 2011, Drug Metabolism and Disposition.

Pharmacokinetics and disposition of recombinant human osteoprotegerin (rhOPG) after intravenous administration in female fischer rats

E. Kamiyama, A. Kurihara, Y. Miyaji, 2009, Xenobiotica; the fate of foreign compounds in biological systems.

Use of an intravenous microdose of 14C-labeled drug and accelerator mass spectrometry to measure absolute oral bioavailability in dogs; cross-comparison of assay methods by accelerator mass spectrometry and liquid chromatography-tandem mass spectrometry.

Toshihiko Ikeda, Yoshihiro Miyaji, Kenji Kawai, 2009, Drug metabolism and pharmacokinetics.

Relationship between inhibition of pressor response to angiotensin I and blood concentration of captopril following a single oral administration to dogs.

H. Shindo, K. Kawai, T. Ikeda, 1981, European journal of pharmacology.

Assessment of the radiochemical design of antibodies with a metabolizable linkage for target-selective radioactivity delivery.

H. Sakahara, J. Konishi, H. Saji, 1998, Bioconjugate chemistry.

Synthesis of [2-14C] griseolic acid 9′-(4-acetoxy-3-methoxybenzyl)ester, a antiglaucoma agent

K. Hirai, K. Kawai, Susumu Sato, 1993 .

Studies on the metabolism of D- and L-isomers of 3,4-dihydroxyphenylalanine (DOPA). V. Mechanism of intestinal absorption of D- and L-DOPA-14C in rats.

H. Shindo, K. Kawai, T. Komai, 1973, Chemical & pharmaceutical bulletin.

STUDIES ON INTESTINAL ABSORPTION OF PIVAMPICILLIN AND SPECIES DIFFERENCE IN THE INTESTINAL ESTERASE ACTIVITY

K. Fukuda, H. Shindo, K. Kawai, 1978 .

Studies on drug metabolism by use of isotopes. XV. Stability of deuterium-label in p-hydroxylation of l-ephedrine.

S. Baba, K. Kawai, 1975, Chemical & pharmaceutical bulletin.

Studies on drug metabolism by use of isotopes. XVII. Mass spectrometric quantification of urinary metabolites of deuterated l-ephedrine in man.

S. Baba, K. Kawai, 1975, Chemical & pharmaceutical bulletin.

Studies on drug metabolism by use of isotopes. XIII. Isotope effect on metabolism of deuterated 1-ephedrine.

S. Baba, K. Kawai, 1974, Chemical & pharmaceutical bulletin.

[Studies on drug metabolism by use of isotopes. XII. Quantitative analysis of 22H-labeled compounds on benzene ring by mass spectrometry (author's transl)].

S. Baba, Y. Shida, K. Kawai, 1974, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

[Studies on drug metabolism by use of isotopes. XI. Studies on synthesis and physiochemical features of 2H-labeled l-ephedrine on benzene ring (author's transl)].

S. Baba, K. Kawai, 1974, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

[Studies on the metabolism in man by use of 2H-labelled drug. Quantitative determination of the metabolites of 1-ephedrine(aron. -2H S5) in man].

Y. Shida, K. Kawai, S. Baba, 1972, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

Stereoselective Metabolism of New Oral Anti-diabetic Agent Troglitazone Stereoisomers in Liver

T. Tokui, K. Kawai, F. Tsuruta, 1998 .