Mandy Yim

发表

Maximizing Antibody Production in a Targeted Integration Host by Optimization of Subunit Gene Dosage and Position.

B. Snedecor, David Shaw, Michael W. Laird, 2020, Biotechnology progress.

Evaluation of heavy chain C‐terminal deletions on productivity and product quality of monoclonal antibodies in Chinese hamster ovary (CHO) cells

B. Snedecor, Michael W. Laird, S. Misaghi, 2017, Biotechnology progress.

Endothelial intercellular cell adhesion molecule 1 contributes to cell aggregate formation in CHO cells cultured in serum‐free media

B. Snedecor, W. Sandoval, David Shaw, 2019, Biotechnology progress.

Probing the importance of clonality: Single cell subcloning of clonally derived CHO cell lines yields widely diverse clones differing in growth, productivity, and product quality

B. Snedecor, David Shaw, Michael W. Laird, 2018, Biotechnology progress.

Achieving greater efficiency and higher confidence in single‐cell cloning by combining cell printing and plate imaging technologies

Mandy Yim, David Shaw, David Shaw, 2018, Biotechnology progress.

Development and characterization of an automated imaging workflow to generate clonally‐derived cell lines for therapeutic proteins

Andy Lin, Mandy Yim, Joni Tsukuda, 2018, Biotechnology progress.

Supplementation of Nucleosides During Selection can Reduce Sequence Variant Levels in CHO Cells Using GS/MSX Selection System

B. Snedecor, K. H. Hoi, David Shaw, 2018, Biotechnology journal.

Development of a targeted integration Chinese hamster ovary host directly targeting either one or two vectors simultaneously to a single locus using the Cre/Lox recombinase‐mediated cassette exchange system

B. Snedecor, Z. Modrušan, Michael W. Laird, 2021, Biotechnology progress.

Beating the odds: The poisson distribution of all input cells during limiting dilution grossly underestimates whether a cell line is clonally‐derived or not

Y. Zhou, B. Snedecor, David Shaw, 2018, Biotechnology progress.

Concurrent transfection of randomized transgene configurations into targeted integration CHO host is an advantageous and cost‐effective method for expression of complex molecules

B. Snedecor, S. Misaghi, S. Louie, 2020, Biotechnology journal.

Taming hyperactive hDNase I: Stable inducible expression of a hyperactive salt‐ and actin‐resistant variant of human deoxyribonuclease I in CHO cells

B. Snedecor, S. Misaghi, S. Louie, 2017, Biotechnology progress.

FX knockout CHO hosts can express desired ratios of fucosylated or afucosylated antibodies with high titers and comparable product quality

B. Snedecor, David Shaw, S. Misaghi, 2017, Biotechnology and bioengineering.