D. Neau

发表

Mechanistic Insights into Validoxylamine A 7'-Phosphate Synthesis by VldE Using the Structure of the Entire Product Complex

M. Cavalier, Yong-Hwan Lee, T. Mahmud, 2012, PloS one.

Mechanistic Implications of the Unique Structural Features and Dimerization of the Cytoplasmic Domain of the Pseudomonas Sigma Regulator, PupR.

S. Chakravarthy, Huaying Zhao, A. Balbo, 2015, Biochemistry.

Covalent Small Molecule Inhibitors of Ca2+-Bound S100B

Timothy L. Foley, David J Weber, A. Jadhav, 2014, Biochemistry.

C-terminal modification of the insulin B:11–23 peptide creates superagonists in mouse and human type 1 diabetes

P. Marrack, J. Kappler, S. Dai, 2017, Proceedings of the National Academy of Sciences.

Crystal Structure of Carboxyltransferase from Staphylococcus aureus Bound to the Antibacterial Agent Moiramide B.

G. Waldrop, S. Pakhomova, Carol M. Taylor, 2016, Biochemistry.

Data publication with the structural biology data grid supports live analysis

Oleg V. Tsodikov, Stephen C. Blacklow, Amedeo Caflisch, 2016, Nature Communications.

Peptide Centric Vβ Specific Germline Contacts Shape a Specialist T Cell Response

C. Deane, P. Thomas, W. K. Wong, 2022, Frontiers in Immunology.

BECN2 interacts with ATG14 through a metastable coiled‐coil to mediate autophagy

S. Chakravarthy, B. Levine, S. Sinha, 2017, Protein science : a publication of the Protein Society.

Helical remodeling augments 5-lipoxygenase activity in the synthesis of proinflammatory mediators

M. Newcomer, N. Gilbert, D. Neau, 2022, The Journal of biological chemistry.

Small Molecule Inhibitors of Ca(2+)-S100B Reveal Two Protein Conformations.

Alexander D. MacKerell, M. I. Ansari, David J Weber, 2016, Journal of medicinal chemistry.

Optimization and Mechanistic Characterization of Pyridopyrimidine Inhibitors of Bacterial Biotin Carboxylase.

F. Cohen, J. Pogliano, G. Waldrop, 2019, Journal of medicinal chemistry.

The Structure of Human 5-Lipoxygenase

A. Brash, M. Newcomer, N. Gilbert, 2011, Science.

An ensemble of lipoxygenase structures reveals novel conformations of the Fe coordination sphere

A. Brash, M. Newcomer, S. Pakhomova, 2019, Protein science : a publication of the Protein Society.

The 1.85 A structure of an 8R-lipoxygenase suggests a general model for lipoxygenase product specificity.

A. Brash, M. Newcomer, N. Gilbert, 2009, Biochemistry.

Expression of an 8R-Lipoxygenase From the Coral Plexaura homomalla.

M. Newcomer, N. Gilbert, D. Neau, 2018, Methods in enzymology.

Improving protein crystal quality by selective removal of a Ca(2+)-dependent membrane-insertion loop.

M. Newcomer, A. Dassey, N. Gilbert, 2007, Acta crystallographica. Section F, Structural biology and crystallization communications.

Structural Basis of the Enhanced Pollutant-Degrading Capabilities of an Engineered Biphenyl Dioxygenase

J. Bolin, Pravindra Kumar, M. Sylvestre, 2016, Journal of bacteriology.

Title : The structural basis of the enhanced pollutant-degrading capabilities of an engineered 1 biphenyl dioxygenase 2 Running Title : Structural Studies of BphAE variant II 9 3

J. Bolin, Pravindra Kumar, M. Sylvestre, 2016 .

Directed Evolution of a Ring-cleaving Dioxygenase for Polychlorinated Biphenyl Degradation*

J. Bolin, L. Eltis, Pascal D. Fortin, 2005, Journal of Biological Chemistry.

Rotational and Translational Diffusion of a Rodlike Virus in Random Coil Polymer Solutions

P. Russo, Z. Bu, Z. Küçükyavuz, 1997 .

Structural basis for ligand and heparin binding to neuropilin B domains

H. Bellamy, C. V. Vander Kooi, D. Leahy, 2007, Proceedings of the National Academy of Sciences.

The three-dimensional structure of the biotin carboxylase-biotin carboxyl carrier protein complex of E. coli acetyl-CoA carboxylase.

G. Waldrop, S. Pakhomova, T. C. Broussard, 2013, Structure.

The Structure of Human 15-Lipoxygenase-2 with a Substrate Mimic*

M. Newcomer, S. Bartlett, D. Neau, 2014, The Journal of Biological Chemistry.

Structural and mechanistic insights into 5-lipoxygenase inhibition by natural products

O. Werz, M. Newcomer, U. Garscha, 2020, Nature Chemical Biology.

Conversion of human 5‐lipoxygenase to a 15‐lipoxygenase by a point mutation to mimic phosphorylation at Serine‐663

A. Brash, M. Newcomer, Z. Rui, 2012 .

Novel Vβ specific germline contacts shape an elite controller T cell response

C. Deane, P. Thomas, W. K. Wong, 2020, bioRxiv.

Molecular basis of the fructose‐2,6‐bisphosphatase reaction of PFKFB3: Transition state and the C‐terminal function

M. Cavalier, Yong-Hwan Lee, Song-Gun Kim, 2012, Proteins.

Structural insights into the binding of the human receptor for advanced glycation end products (RAGE) by S100B, as revealed by an S100B-RAGE-derived peptide complex.

S. Vetter, V. Indurthi, D. Neau, 2015, Acta crystallographica. Section D, Biological crystallography.

Helical remodeling augments 5-lipoxygenase activity

M. Newcomer, N. Gilbert, D. Neau, 2022, bioRxiv.

Identification and analysis of a bottleneck in PCB biodegradation

J. Bolin, L. Eltis, Halim Maaroufi, 2002, Nature Structural Biology.

How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes

P. Marrack, J. Kappler, S. Dai, 2019, Science Immunology.

Crystal structure of heart 6‐phosphofructo‐2‐kinase/fructose‐2,6‐bisphosphatase (PFKFB2) and the inhibitory influence of citrate on substrate binding

Yong-Hwan Lee, Song-Gun Kim, Y. Yim, 2017, Proteins.

Structure-Based Development of Small Molecule PFKFB3 Inhibitors: A Framework for Potential Cancer Therapeutic Agents Targeting the Warburg Effect

Yong-Hwan Lee, I. Sehgal, D. Neau, 2011, PloS one.

The Center for Advanced Microstructures and Devices (CAMD): New Opportunities and New Facilities

H. Bellamy, J. Goettert, C. Kumar, 2007 .

Characterization of the structure and function of Klebsiella pneumoniae allantoin racemase.

S. Ealick, J. French, D. Neau, 2011, Journal of molecular biology.

Crystal Structure of a Lipoxygenase in Complex with Substrate

A. Brash, M. Newcomer, G. Bender, 2014, The Journal of Biological Chemistry.

Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase.

G. Waldrop, S. Pakhomova, T. C. Broussard, 2015, Biochemistry.

Kinetic and structural investigations of novel inhibitors of human epithelial 15-lipoxygenase-2.

Adam Yasgar, A. Jadhav, A. Simeonov, 2021, Bioorganic & medicinal chemistry.

OF 8 R-LIPOXYGENASE ARACHIDONIC ACID-BINDING SITE Complex with Substrate : THE Crystal Structure of a Lipoxygenase in Protein Structure and Folding :

A. Brash, M. Newcomer, G. Bender, 2014 .

Two Divalent Metal Ions and Conformational Changes Play Roles in the Hammerhead Ribozyme Cleavage Reaction.

David Neau, B. Golden, Aamir Mir, 2015, Biochemistry.