L. Rajagopal

发表

Pimavanserin augments the efficacy of atypical antipsychotic drugs in a mouse model of treatment-refractory negative symptoms of schizophrenia

H. Meltzer, E. Burstein, L. Rajagopal, 2021, Behavioural Brain Research.

Effects of NBI-98782, a selective vesicular monoamine transporter 2 (VMAT2) inhibitor, on neurotransmitter efflux and phencyclidine-induced locomotor activity: Relevance to tardive dyskinesia and antipsychotic action

H. Meltzer, A. Kudwa, D. Grigoriadis, 2020, Pharmacology Biochemistry and Behavior.

GLYX-13 (rapastinel) ameliorates subchronic phencyclidine- and ketamine-induced declarative memory deficits in mice

H. Meltzer, J. Moskal, J. Burgdorf, 2016, Behavioural Brain Research.

Repeated administration of rapastinel produces exceptionally prolonged rescue of memory deficits in phencyclidine-treated mice

H. Meltzer, Mei Huang, P. Banerjee, 2022, Behavioural Brain Research.

Serotonin (5-HT)1A receptor agonism and 5-HT7 receptor antagonism ameliorate the subchronic phencyclidine-induced deficit in executive functioning in mice

H. Meltzer, B. W. Massey, L. Rajagopal, 2016, Psychopharmacology.

The novel object recognition test in rodents in relation to cognitive impairment in schizophrenia.

Herbert Y Meltzer, Mei Huang, H. Meltzer, 2014, Current pharmaceutical design.

Animal models of cognitive dysfunction and negative symptoms of schizophrenia: focus on NMDA receptor antagonism.

Shikha Snigdha, Ben Grayson, Joanna C Neill, 2010, Pharmacology & therapeutics.

Neurosteroid pregnenolone sulfate, alone, and as augmentation of lurasidone or tandospirone, rescues phencyclidine-induced deficits in cognitive function and social interaction

H. Meltzer, L. Rajagopal, D. Soni, 2018, Behavioural Brain Research.

Translating the N-methyl-D-aspartate receptor antagonist model of schizophrenia to treatments for cognitive impairment in schizophrenia.

H. Meltzer, Mei Huang, Y. Oyamada, 2013, The international journal of neuropsychopharmacology.

Comparative effect of lurasidone and blonanserin on cortical glutamate, dopamine, and acetylcholine efflux: role of relative serotonin (5‐HT)2A and DA D2 antagonism and 5‐HT1A partial agonism

H. Meltzer, Mei Huang, Y. Oyamada, 2014, Journal of neurochemistry.

The allosteric dopamine D1 receptor potentiator, DETQ, ameliorates subchronic phencyclidine-induced object recognition memory deficits and enhances cortical acetylcholine efflux in male humanized D1 receptor knock-in mice

H. Meltzer, K. Svensson, Mei Huang, 2019, Behavioural Brain Research.

Combined serotonin (5-HT)1A agonism, 5-HT2A and dopamine D2 receptor antagonism reproduces atypical antipsychotic drug effects on phencyclidine-impaired novel object recognition in rats

H. Meltzer, Y. Oyamada, M. Horiguchi, 2015, Behavioural Brain Research.

Depolarizing GABAA current in the prefrontal cortex is linked with cognitive impairment in a mouse model relevant for schizophrenia

M. Martina, H. Meltzer, Haram R. Kim, 2021, Science Advances.

Dopamine D3 receptor antagonism contributes to blonanserin-induced cortical dopamine and acetylcholine efflux and cognitive improvement

H. Meltzer, Mei Huang, Y. Oyamada, 2015, Pharmacology Biochemistry and Behavior.

5-HT1A parital agonism and 5-HT7 antagonism restore episodic memory in subchronic phencyclidine-treated mice: role of brain glutamate, dopamine, acetylcholine and GABA

H. Meltzer, Mei Huang, L. Rajagopal, 2018, Psychopharmacology.

RP5063, an atypical antipsychotic drug with a unique pharmacologic profile, improves declarative memory and psychosis in mouse models of schizophrenia

M. Cantillon, H. Meltzer, L. Bhat, 2017, Behavioural Brain Research.

Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment

K. Yamakawa, H. Kasai, I. Graef, 2024, eLife.

Radiofrequency catheter ablation in a patient with giant left atrium and permanent atrial fibrillation: maintenance of sinus rhythm at 1 year.

M. Nair, L. Rajagopal, S. Rajagopal, 2008, Indian heart journal.

Phencyclidine (PCP)–Induced Deficits in Novel Object Recognition

H. Meltzer, N. Neugebauer, Mei Huang, 2016 .

NU-1223, a simplified analog of alstonine, with 5-HT2cR agonist-like activity, rescues memory deficit and positive and negative symptoms in subchronic phencyclidine mouse model of schizophrenia

H. Meltzer, Mei Huang, A. Csakai, 2023, Behavioural Brain Research.

TPA-023 attenuates subchronic phencyclidine-induced declarative and reversal learning deficits via GABAA receptor agonist mechanism: possible therapeutic target for cognitive deficit in schizophrenia

H. Meltzer, Mei Huang, L. Rajagopal, 2018, Neuropsychopharmacology.

Translating the N-methyl-D-aspartate receptor antagonist model of schizophrenia to treatments for cognitive impairment in schizophrenia.

H. Meltzer, Mei Huang, Y. Oyamada, 2013, The international journal of neuropsychopharmacology.

Dopamine D3 receptor antagonism contributes to blonanserin-induced cortical dopamine and acetylcholine efflux and cognitive improvement

H. Meltzer, Mei Huang, Y. Oyamada, 2015, Pharmacology Biochemistry and Behavior.

Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment

Akinobu Matsumoto, Y. Komine, B. Kaang, 2021, bioRxiv.

Neonatal phencyclidine (PCP) induced deficits in rats : a behavioural investigation of relevance to schizophrenia

L. Rajagopal, 2011 .