M. Kittelmann

发表

Isolation and classification of acetic acid bacteria from high percentage vinegar fermentations

H. G. Trüper, M. Kittelmann, W. Stamm, 2004, Applied Microbiology and Biotechnology.

Non‐clinical characterization of the disposition of EMA401, a novel small molecule angiotensin II type 2 receptor (AT2R) antagonist

M. Kittelmann, R. Murgasova, Ester Tor Carreras, 2020, Biopharmaceutics & drug disposition.

3'-Demethoxy-3'-hydroxystaurosporine-O-methyltransferase from Streptomyces longisporoflavus catalyzing the last step in the biosynthesis of staurosporine.

H. Zähner, K. Goeke, O. Ghisalba, 1998, The Journal of antibiotics.

Biocatalysis in the Fine Chemical and Pharmaceutical Industries

Joseph P. Adams, Peter W. Sutton, Roger M. Howard, 2012 .

Draft Genome Sequences of Three Actinobacteria Strains Presenting New Candidate Organisms with High Potentials for Specific P450 Cytochromes

V. Urlacher, Y. Vainshtein, A. Vogel, 2017, Genome Announcements.

CMP-N-acetyl neuraminic-acid synthetase from Escherichia coli: fermentative production and application for the preparative synthesis of CMP-neuraminic acid

U. Kragl, C. Wandrey, O. Ghisalba, 1995, Applied Microbiology and Biotechnology.

N‐Acetylneuraminic Acid From a Rare Chemical from Natural Sources to a Multikilogram Enzymatic Synthesis for Industrial Application

U. Kragl, C. Wandrey, O. Ghisalba, 1995 .

Preparative Enzymatic Synthesis of Activated Neuraminic Acid by Using a Microbial Enzyme

U. Kragl, C. Wandrey, O. Ghisalba, 1992, Annals of the New York Academy of Sciences.

Isolation and characterization of highly (R)-specific N-acetyl-1-phenylethylamine amidohydrolase, a new enzyme from Arthrobacter aurescens AcR5b

O. Ghisalba, M. Kittelmann, K. Laumen, 1997, Applied Microbiology and Biotechnology.

PDFlib PLOP: PDF Linearization, Optimization, Protection Page inserted by evaluation version

U. Kragl, C. Wandrey, O. Ghisalba, 2005 .

Human UDP-glucuronosyltransferase UGT1A4 forms tertiary N-glucuronides predominately with the energetically less favored tautomer of substituted 1H-indazole (benzpyrazole)

M. Kittelmann, A. Fredenhagen, J. Kühnöl, 2017, Journal of Analytical Science and Technology.

Biocatalytic Synthesis and Structure Elucidation of Cyclized Metabolites of the Deacetylase Inhibitor Panobinostat (LBH589)

P. Atadja, M. Shultz, Ping Wang, 2012, Drug Metabolism and Disposition.

Microbial production, purification, and characterization of (S)-specific N-acetyl-2-amino-1-phenyl-4-pentene amidohydrolase from Rhodococcus globerulus K1/1

P. Wahl, O. Ghisalba, M. Kittelmann, 1999, Applied Microbiology and Biotechnology.

Chemo-enzymatic approaches for the creation of novel chiral building blocks and reagents for pharmaceutical applications

O. Ghisalba, M. Kittelmann, K. Laumen, 2002 .

New Biocatalytic Approaches for the Synthesis of Chiral Drugs, Intermediates, and Substrates

O. Ghisalba, M. Kittelmann, K. Laumen, 1998 .

Expression of recombinant human flavin monooxygenase and moclobemide-N-oxide synthesis on multi-mg scale.

Anton Glieder, Sandra Abad, Beat Wirz, 2012, Chemical communications.

Preparative Enzymatic Synthesis of the Acylglucuronide of Mycophenolic Acid

E. Francotte, O. Ghisalba, L. Oberer, 2003 .

Gas-Phase Rearrangement of the O-Glucuronide of Vildagliptin Forms Product-Ion Fragments Suggesting Wrongly an N-Glucuronide

L. Oberer, M. Kittelmann, A. Fredenhagen, 2018, Drug Metabolism and Disposition.

Human FMO2-based microbial whole-cell catalysts for drug metabolite synthesis

Martina Geier, Beat Wirz, Matthias Kittelmann, 2015, Microbial Cell Factories.

Production of Recombinant Human Aldehyde Oxidase in Escherichia coli and Optimization of Its Application for the Preparative Synthesis of Oxidized Drug Metabolites

Anton Glieder, Sandra Abad, Matthias Kittelmann, 2014 .

The occurrence of bacteriophages in spirit vinegar fermentation

H. G. Trüper, M. Kittelmann, W. Stamm, 2004, Applied Microbiology and Biotechnology.

Metabolism and Disposition of the Metabotropic Glutamate Receptor 5 Antagonist (mGluR5) Mavoglurant (AFQ056) in Healthy Subjects

Yi Jin, Thierry Wolf, Matthias Kittelmann, 2013, Drug Metabolism and Disposition.

Isolation and Characterization of N-Acetyldehydroleucine Acylase, a New Enzyme from Zoogloea ramigera

M. Kula, M. Kittelmann, 1992 .

A novel cytochrome P450 mono‐oxygenase from Streptomyces platensis resembles activities of human drug metabolizing P450s

V. Urlacher, A. Vogel, S. Lütz, 2018, Biotechnology and bioengineering.

The Development of Biocatalysis as a Tool for Drug Discovery.

S. Lütz, Katrin Rosenthal, Radka Snajdrova, 2020, Chimia (Basel).

Recombinant human cytochrome P450 monooxygenases for drug metabolite synthesis.

Matthias Kittelmann, S. Lütz, K. Schroer, 2010, Biotechnology and Bioengineering.

Identification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and Humans

J. Mangold, O. Simon, H. Einolf, 2016, Drug Metabolism and Disposition.

Syk inhibitors with high potency in presence of blood.

Jianwei Che, E. Vangrevelinghe, Christian C. Lee, 2014, Bioorganic & medicinal chemistry letters.

Human flavin monooxygenase 2: Heterologous expression in E. coli and API modification

A. Glieder, M. Geier, S. Lütz, 2014 .

Recombinant Yeast and Bacteria that Express Human P450s: Bioreactors for Drug Discovery, Development, and Biotechnology

C. Wolf, T. Friedberg, O. Ghisalba, 2007 .

Metabolism and Disposition of the Metabotropic Glutamate Receptor 5 Antagonist ( mGluR 5 ) Mavoglurant ( AFQ 056 ) in Healthy Subjects

R. Woessner, L. Leuthold, A. Chakraborty, 2013 .

Human xanthine oxidase recombinant in E. coli: A whole cell catalyst for preparative drug metabolite synthesis.

Beat Wirz, Matthias Kittelmann, Margit Winkler, 2016, Journal of biotechnology.

Preparation of Drug Metabolites Using Fungal and Bacterial Strains

O. Ghisalba, M. Kittelmann, 2007 .