Hiromi Ogata

发表

Novel bis-Tetrahydrofuranylurethane-Containing Nonpeptidic Protease Inhibitor (PI) UIC-94017 (TMC114) with Potent Activity against Multi-PI-Resistant Human Immunodeficiency Virus In Vitro

Irene T. Weber, Robert W. Harrison, Patra Volarath, 2003, Antimicrobial Agents and Chemotherapy.

Association behavior and control of the quality of cancer therapeutic bispecific diabodies expressed in Escherichia coli

Yoshikazu Tanaka, I. Kumagai, H. Nakazawa, 2020 .

Multimerization of anti‐(epidermal growth factor receptor) IgG fragments induces an antitumor effect: the case for humanized 528 scFv multimers

I. Kumagai, M. Umetsu, S. Furumoto, 2013, The FEBS journal.

In vitro and in vivo antitumor effects of recombinant bispecific antibodies based on humanized anti-EGFR antibody.

M. Unno, T. Kudo, I. Kumagai, 2011, Oncology reports.

Rearranging the domain order of a diabody-based IgG-like bispecific antibody enhances its antitumor activity and improves its degradation resistance and pharmacokinetics

M. Unno, T. Omasa, T. Kudo, 2014, mAbs.

Structural considerations for functional anti-EGFR × anti-CD3 bispecific diabodies in light of domain order and binding affinity

K. Makabe, I. Kumagai, T. Kumagai, 2018, Oncotarget.

Domain order of a bispecific diabody dramatically enhances its antitumor activity beyond structural format conversion: the case of the hEx3 diabody.

M. Unno, T. Kudo, I. Kumagai, 2013, Protein engineering, design & selection : PEDS.

The current status of, and challenges in, the development of CCR5 inhibitors as therapeutics for HIV-1 infection.

Hiroaki Mitsuya, H. Mitsuya, K. Maeda, 2004, Current opinion in pharmacology.

Spirodiketopiperazine-Based CCR5 Inhibitor Which Preserves CC-Chemokine/CCR5 Interactions and Exerts Potent Activity against R5 Human Immunodeficiency Virus Type 1 In Vitro

H. Mitsuya, K. Maeda, Y. Koh, 2004, Journal of Virology.

Anti‐EGFR scFv tetramer (tetrabody) with a stable monodisperse structure, strong anticancer effect, and a long in vivo half‐life

I. Kumagai, M. Umetsu, S. Furumoto, 2016, FEBS open bio.

Immunodeficiency Virus In Vitro against Multi-PI-Resistant Human UIC-94017 ( TMC 114 ) with Potent Activity Nonpeptidic Protease Inhibitor ( PI )-Tetrahydrofuranylurethane-Containing bis Novel

Irene T. Weber, Robert W. Harrison, Patra Volarath, 2003 .

Build-up functionalization of anti-EGFR × anti-CD3 bispecific diabodies by integrating high-affinity mutants and functional molecular formats

T. Omasa, I. Kumagai, M. Umetsu, 2020, Scientific Reports.

In vitro and in vivo antitumor effects of recombinant bispecific antibodies based on humanized anti-EGFR antibody.

M. Unno, T. Kudo, I. Kumagai, 2011, Oncology reports.