J. Mikuni

发表

Discovery of a small molecule inhibitor targeting dengue virus NS5 RNA-dependent RNA polymerase

M. Shirouzu, T. Honma, H. Shimizu, 2019, PLoS neglected tropical diseases.

Activity cliff for 7-substituted pyrrolo-pyrimidine inhibitors of HCK explained in terms of predicted basicity of the amine nitrogen.

M. Shirouzu, T. Honma, Hitomi Yuki, 2017, Bioorganic & medicinal chemistry.

Identification of novel drug-resistant EGFR mutant inhibitors by in silico screening using comprehensive assessments of protein structures.

S. Yokoyama, M. Shirouzu, T. Honma, 2012, Bioorganic & medicinal chemistry.

A Pyrrolo-Pyrimidine Derivative Targets Human Primary AML Stem Cells in Vivo

Satoshi Tanaka, Shigeyuki Yokoyama, Hiroshi Kajita, 2013, Science Translational Medicine.

Crystal structures of the S6K1 kinase domain in complexes with inhibitors

S. Yokoyama, M. Shirouzu, T. Honma, 2014, Journal of Structural and Functional Genomics.

Protein ligand interaction analysis against new CaMKK2 inhibitors by use of X-ray crystallography and the fragment molecular orbital (FMO) method.

S. Yokoyama, T. Honma, D. Takaya, 2020, Journal of molecular graphics & modelling.

Kinase crystal identification and ATP-competitive inhibitor screening using the fluorescent ligand SKF86002.

S. Yokoyama, M. Shirouzu, A. Tanaka, 2014, Acta crystallographica. Section D, Biological crystallography.

Phosphorylated and non-phosphorylated HCK kinase domains produced by cell-free protein expression.

S. Yokoyama, T. Terada, M. Shirouzu, 2018, Protein expression and purification.

A fluorescence correlation spectroscopy-based assay for fragment screening of slowly inhibiting protein-peptide interaction inhibitors.

S. Yokoyama, T. Honma, T. Nagano, 2010, Analytical biochemistry.

Identification of novel drug-resistant EGFR mutant inhibitors by in silico screening using comprehensive assessments of protein structures.

S. Yokoyama, M. Shirouzu, T. Honma, 2012, Bioorganic & medicinal chemistry.