Huanqiu Li

发表

Sodium tanshinone IIA sulfonate ameliorates ischemia-induced myocardial inflammation and lipid accumulation in Beagle dogs through NLRP3 inflammasome.

H. Ji, Xing Yu, Qinghua Hu, 2015, International journal of cardiology.

(E)-2-(4-bromophenyl)-1-(2, 4-dihydroxyphenyl)ethanone oxime is a potential therapeutic agent for treatment of hyperuricemia through its dual inhibitory effects on XOD and URAT1.

Kun Hao, Qinghua Hu, Huanqiu Li, 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

HJ22, a Novel derivative of piperine, Attenuates ibotenic acid-induced cognitive impairment, oxidativestress, apoptosis and inflammation via inhibiting the protein-protein interaction of Keap1-Nrf2.

Qinghua Hu, Huanqiu Li, Chunxiao Liu, 2020, International immunopharmacology.

Discovery of Novel Aminotetralines and Aminochromanes as Selective and Competitive Glycine Transporter 1 (GlyT1) Inhibitors.

Justin D Dietrich, A. Vasudevan, J. Sydor, 2018, Journal of medicinal chemistry.

GPR105-Targeted Therapy Promotes Gout Resolution as a Switch Between NETosis and Apoptosis of Neutrophils

Wenjiao Jiang, Kun Hao, Sheng Tian, 2022, Frontiers in Immunology.

Reaction-Based "Off-On" Fluorescent Probe Enabling Detection of Endogenous Labile Fe(2+) and Imaging of Zn(2+)-induced Fe(2+) Flux in Living Cells and Elevated Fe(2+) in Ischemic Stroke.

Yongyi Wei, Fu-Sen Liang, Yanting Cao, 2016, Bioconjugate chemistry.

Development of novel NLRP3-XOD dual inhibitors for the treatment of gout.

Eun Hee Ha, Sheng Tian, E. Ha, 2020, Bioorganic & medicinal chemistry letters.

Therapeutic potential of fucosyltransferases in cancer and recent development of targeted inhibitors.

Sheng Tian, Huanqiu Li, Yixin Lv, 2022, Drug discovery today.

De Novo Design, Synthesis, and Biological Evaluation of 3,4-Disubstituted Pyrrolidine Sulfonamides as Potent and Selective Glycine Transporter 1 Competitive Inhibitors.

Justin D Dietrich, A. Vasudevan, J. Sydor, 2018, Journal of medicinal chemistry.

LSD1 inhibitors for anticancer therapy: a patent review (2017-present)

Sheng Tian, Huanqiu Li, Yixin Lv, 2022, Expert opinion on therapeutic patents.

Engineering Iron Responses in Mammalian Cells by Signal-Induced Protein Proximity.

Yongyi Wei, Fu-Sen Liang, Roushu Zhang, 2017, ACS synthetic biology.

The role of P2Y6R in cardiovascular diseases and recent development of P2Y6R antagonists.

H. Ji, Qian Zhang, Qinghua Hu, 2020, Drug discovery today.

Development of benzoxazole deoxybenzoin oxime and acyloxylamine derivatives targeting innate immune sensors and xanthine oxidase for treatment of gout.

Qinghua Hu, Huanqiu Li, Mingxing Miao, 2018, Bioorganic & medicinal chemistry.

A novel SRSF3 inhibitor, SFI003, exerts anticancer activity against colorectal cancer by modulating the SRSF3/DHCR24/ROS axis

Yun-di Guo, F. Meng, Weipeng Wang, 2022, Cell Death Discovery.

A novel SRSF3 inhibitor, SFI003, exerts anticancer activity against colorectal cancer by modulating the SRSF3/DHCR24/ROS axis

Yun-di Guo, Jing Sun, Hongjiang Zhang, 2022, Cell death discovery.

Neuroprotective Effects of DTIO, A Novel Analog of Nec-1, in Acute and Chronic Stages After Ischemic Stroke

Jie Chen, Wei Li, Yong-ming Zhu, 2018, Neuroscience.

Discovery and computational studies of 2-phenyl-benzoxazole acetamide derivatives as promising P2Y14R antagonists with anti-gout potential.

Sheng Tian, Yifan Zhu, Qinghua Hu, 2021, European journal of medicinal chemistry.

Discovery of Janus Kinase 2 (JAK2) and Histone Deacetylase (HDAC) Dual Inhibitors as a Novel Strategy for the Combinational Treatment of Leukemia and Invasive Fungal Infections.

Guoqiang Dong, Wannian Zhang, C. Sheng, 2018, Journal of medicinal chemistry.

Recent progress on the discovery of NLRP3 inhibitors and their therapeutic potential.

F. Liu, Huanqiu Li, Weiwei Wang, 2020, Current medicinal chemistry.

Discovery of Selective P2Y6R Antagonists with High Affinity and In Vivo Efficacy for Inflammatory Disease Therapy.

Sheng Tian, Duxin Li, Yifan Zhu, 2023, Journal of medicinal chemistry.

Structure-based virtual screening for discovery of paederosidic acid from Paederia scandens as novel P2Y14R antagonist.

Sheng Tian, X. Zhao, Yuxin Li, 2023, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Discovery of novel and potent P2Y14R antagonists via structure-based virtual screening for the treatment of acute gouty arthritis

Sheng Tian, Yingxian Liu, Qinghua Hu, 2020, Journal of advanced research.

Network pharmacology-based analysis of Jin-Si-Wei on the treatment of Alzheimer's disease.

Qinghua Hu, Huanqiu Li, Mengze Zhou, 2023, Journal of ethnopharmacology.

FDW028, a novel FUT8 inhibitor, impels lysosomal proteolysis of B7-H3 via chaperone-mediated autophagy pathway and exhibits potent efficacy against metastatic colorectal cancer

Jie Yang, Sheng Tian, Jing Sun, 2023, Cell death & disease.

Continued exploration of biphenylsulfonamide scaffold as a platform for aggrecanase-1 inhibition.

J. Xiang, L. Xing, S. Tam, 2011, Bioorganic & medicinal chemistry letters.

Targeting P2Y14R protects against necroptosis of intestinal epithelial cells through PKA/CREB/RIPK1 axis in ulcerative colitis

Yifan Zhu, Qinghua Hu, Huanqiu Li, 2024, Nature communications.

Macrophage P2Y6 receptor deletion attenuates atherosclerosis by limiting foam cell formation through phospholipase Cβ/store-operated calcium entry/calreticulin/scavenger receptor A pathways.

Qinghua Hu, Huanqiu Li, Mengze Zhou, 2023, European heart journal.

Comprehensive insights into potential roles of purinergic P2 receptors on diseases: Signaling pathways involved and potential therapeutics.

Yifan Zhu, Qinghua Hu, Huanqiu Li, 2024, Journal of advanced research.

Macrophage P2Y6R activation aggravates psoriatic inflammation through IL-27-mediated Th1 responses

Yifan Zhu, Qinghua Hu, Huanqiu Li, 2024, Acta Pharmaceutica Sinica B.