Y. Long

发表

Targeting drug transport mechanisms for improving platinum-based cancer chemotherapy

R. Broaddus, Jinsong Liu, N. Savaraj, 2015, Expert opinion on therapeutic targets.

Pim-1 inhibitor attenuates trinitrobenzene sulphonic acid induced colitis in the mice.

Yan Zhao, Lingqian Li, Yuan Xie, 2018, Clinics and research in hepatology and gastroenterology.

Pim-1 kinase regulates CD4+T cell differentiation

Yan Zhao, Y. Long, Yueming Shen, 2017 .

Collaboration Between RSK-EphA2 and Gas6-Axl RTK Signaling in Arginine Starvation Response That Confers Resistance to EGFR Inhibitors

N. Savaraj, L. Feun, M. Kuo, 2019, Translational oncology.

Investigation of synergistic mechanism and identification of interaction site of aldose reductase with the combination of gigantol and syringic acid for prevention of diabetic cataract

Dan Chen, Xue Li, Xiaoyong Wei, 2016, BMC Complementary and Alternative Medicine.

Gas6/Axl in arginine-starvation therapy

M. Kuo, W. Tsai, Y. Long, 2015, Oncoscience.

Argininosuccinate synthetase 1 (ASS1) is a common metabolic marker of chemosensitivity for targeted arginine- and glutamine-starvation therapy.

M. Hung, D. Hawke, N. Savaraj, 2017, Cancer letters.

Regulation of the high-affinity copper transporter (hCtr1) expression by cisplatin and heavy metals

N. Savaraj, M. Kuo, H. Chen, 2013, JBIC Journal of Biological Inorganic Chemistry.

Arginine Deiminase Resistance in Melanoma Cells Is Associated with Metabolic Reprogramming, Glucose Dependence, and Glutamine Addiction

M. Wangpaichitr, N. Savaraj, L. Feun, 2013, Molecular Cancer Therapeutics.

Activation of Ras/PI3K/ERK pathway induces c-Myc stabilization to upregulate argininosuccinate synthetase, leading to arginine deiminase resistance in melanoma cells.

Hui-Kuan Lin, N. Savaraj, L. Feun, 2012, Cancer research.

Gas6/Axl is the sensor of arginine-auxotrophic response in targeted chemotherapy with arginine-depleting agents

I. Wistuba, J. Rodriguez-Canales, J. T. Chang, 2016, Oncogene.

Mechanistic Basis for Overcoming Platinum Resistance Using Copper Chelating Agents

G. Mills, R. Kurzrock, B. Hennessy, 2012, Molecular Cancer Therapeutics.

Therapeutics , Targets , and Chemical Biology Activation of Ras / PI 3 K / ERK Pathway Induces c-Myc Stabilization to Upregulate Argininosuccinate Synthetase , Leading toArginineDeiminaseResistance inMelanomaCells

Hui-Kuan Lin, N. Savaraj, L. Feun, 2012 .

Activation of mitochondrial ATP-sensitive potassium channels improves rotenone-related motor and neurochemical alterations in rats.

Gang Hu, Yan Long, Fang Wang, 2005, The international journal of neuropsychopharmacology.

Cisplatin-induced synthetic lethality to arginine-starvation therapy by transcriptional suppression of ASS1 is regulated by DEC1, HIF-1α, and c-Myc transcription network and is independent of ASS1 promoter DNA methylation

Jeffrey T. Chang, M. Estecio, M. Wangpaichitr, 2016, Oncotarget.

Mechanisms of l-Arginine-Auxotrophic Response and Their Cancer Therapeutic Implications

N. Savaraj, L. Feun, M. Kuo, 2017 .

Combined IL-2, agonistic CD3 and 4-1BB stimulation preserve clonotype hierarchy in propagated non-small cell lung cancer tumor-infiltrating lymphocytes

P. Shah, A. Maitra, J. Roth, 2022, Journal for ImmunoTherapy of Cancer.

Chromatin remodeling system p300-HDAC2-Sin3A is involved in Arginine Starvation-Induced HIF-1α Degradation at the ASS1 promoter for ASS1 Derepression

Jeffrey T. Chang, N. Savaraj, L. Feun, 2017, Scientific Reports.

Systematic administration of iptakalim, an ATP‐sensitive potassium channel opener, prevents rotenone‐induced motor and neurochemical alterations in rats

Gang Hu, Fang Wang, Yan Long, 2005, Journal of neuroscience research.