A. Bristow

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The proinsulin content of commercial bovine insulin formulations

N. Sutcliffe, A. Bristow, 1984, The Journal of pharmacy and pharmacology.

IL-1-Driven Endogenous IL-10 Production Protects Against the Systemic and Local Acute Inflammatory Response Following Intestinal Reperfusion Injury1

M. Teixeira, S. Poole, D. G. Souza, 2003, The Journal of Immunology.

Development of a two-site immunoradiometric assay for rat/human corticotrophin-releasing factor. Application to the measurement of interleukin-1 beta-stimulated production of hypothalamic CRF in vitro.

P. Hagan, S. Poole, F. Tilders, 1993, Journal of immunological methods.

A simple sensitive bioassay for interleukin-1 which is unresponsive to 10(3) U/ml of interleukin-2.

C. Bird, R. Thorpe, A. Gearing, 1987, Journal of immunological methods.

Insulin Increases Plasma Somatomedin C (IGF‐1) Concentrations in Adult Type 1 Diabetic Patientss

P. Grant, M. Stickland, R. Clarke, 1989, Diabetic medicine : a journal of the British Diabetic Association.

Recombinant-DNA-derived insulin analogues as potentially useful therapeutic agents.

A. Bristow, 1993, Trends in biotechnology.

Dual Effect of Central Injection of Recombinant Rat Interleukin-4 on Lipopolysaccharide-Induced Sickness Behavior in Rats

R. Dantzer, R. Bluthé, J. Lestage, 2002, Neuropsychopharmacology.

Biological activity and brain actions of recombinant rat interleukin-1alpha and interleukin-1beta.

R. Dantzer, N. Rothwell, A. van Dam, 1998, European cytokine network.

Expression and regulation of interleukin‐10 and interleukin‐10 receptor in rat astroglial and microglial cells

J. Leysen, A. Wierinckx, A. van Dam, 2002, The European journal of neuroscience.

Intestinal Reperfusion Injury Acute Inflammatory Response Following Protects Against the Systemic and Local IL-1-Driven Endogenous IL-10 Production

M. Teixeira, S. Poole, R. Guabiraba, 2003 .

Interleukin-1β as a potent hyperalgesic agent antagonized by a tripeptide analogue

S. Ferreira, S. Poole, B. B. Lorenzetti, 1988, Nature.

The International Reference Reagent for insulin-like growth factor-I.

R. E. Das, A. Bristow, R. Gooding, 1990, The Journal of endocrinology.

Differential regulation of type I and type II interleukin‐1 receptors in focal brain inflammation

V. Perry, S. Campbell, D. Anthony, 2005, The European journal of neuroscience.

Intracerebral NMDA Injection Stimulates Production of Interleukin‐1β in Perinatal Rat Brain

F. Silverstein, P. Hagan, S. Poole, 1996, Journal of neurochemistry.

Development of a stable chemically cross-linked erythropoietin dimer for use in the quality control of erythropoietin therapeutic products

C. Burns, A. Costanzo, A. Bristow, 2019, Analytical and Bioanalytical Chemistry.

Endogenous Interleukin‐10 is Required for the Defervescence of Fever Evoked by Local Lipopolysaccharide‐Induced and Staphylococcus Aureus‐Induced Inflammation in Rats

C. Ball, S. Poole, D. Mitchell, 2003, The Journal of physiology.

Corticotrophin-releasing hormone (CRH)-binding protein interference with CRH antibody binding: implications for direct CRH immunoassay.

C. Wolfe, P. Hagan, S. Poole, 1995, The Journal of endocrinology.

Deletion of the ventral noradrenergic bundle obliterates the early ACTH response after systemic LPS, independently from the plasma IL-1β surge

S. Gaillet, I. Assenmacher, L. Givalois, 1995, Endocrine.

Corticotrophin-releasing factor as a mediator of the acute-phase response in rats, mice and rabbits.

P. Hagan, S. Poole, A. Bristow, 1993, The Journal of endocrinology.

Central injection of interleukin-13 potentiates LPS-induced sickness behavior in rats

R. Dantzer, R. Bluthé, J. Lestage, 2001, Neuroreport.

Detection of host‐derived contaminants in products of recombinant DNA technology in E. coli: a comparison of silver‐staining and immunoblotting

A. Bristow, R. Gooding, 1985, The Journal of pharmacy and pharmacology.

Development and application of radioimmunoassays for interleukin-1α and interleukin-1β

S. Poole, S. Selkirk, B. Rafferty, 1989 .

An ELISA method to estimate the mono ADP-ribosyltransferase activities: e.g in pertussis toxin and vaccines.

C. Ball, C. Yuen, S. Tanley, 2018, Analytical biochemistry.

The Role of the Vagus Nerve in Mediating the Long‐Term Anorectic Effects of Leptin

G. Luheshi, C. Rummel, A. Bristow, 2007, Journal of neuroendocrinology.

High-resolution structure of murine interleukin 1 homologue IL-1F5 reveals unique loop conformations for receptor binding specificity.

Xue Yuan Pei, Adrian F Bristow, N. Gay, 2003, Biochemistry.

Analysis of therapeutic growth hormone preparations: report of an interlaboratory collaborative study on growth hormone assay methodologies.

S. Jeffcoate, A. Bristow, Adrian Bristow, 1992, Biologicals : journal of the International Association of Biological Standardization.

Cyclic nucleotide-dependent phosphorylation of endogenous proteins in bovine adrenocortical cell membranes.

R. Rodnight, D. Schulster, A. Bristow, 1981, Biochimica et biophysica acta.

Reversed-phase high-performance liquid chromatography of human thyroid-stimulating hormone.

N. Sutcliffe, A. Bristow, C. Wilson, 1983, Journal of chromatography.

ACTH (corticotropin)-receptor mediated events in the adrenocortical cell membrane.

D. Salmon, D. Schulster, A. Bristow, 1981, Biochemical Society transactions.

Effects of ACTH (corticotropin) analogues on steroidogenesis and cyclic AMP in rat adrenocortical cells. Evidence for two different steroidogenically responsive receptors.

J. Fauchère, R. Schwyzer, D. Schulster, 1980, The Biochemical journal.

WHO international reference reagents for human proinsulin and human insulin C-peptide.

R. E. Das, A. Bristow, 1988, Journal of biological standardization.

Immunosuppressive activity of corticotrophin-releasing factor. Inhibition of interleukin-1 and interleukin-6 production by human mononuclear cells.

P. Hagan, S. Poole, A. Bristow, 1992, The Biochemical journal.

Rat tumour necrosis factor-alpha: expression in recombinant Pichia pastoris, purification, characterization and development of a novel ELISA.

C. Ball, G. Tarrant, S. Poole, 1999, European cytokine network.

Rat interleukin 6: expression in recombinant Escherichia coli, purification and development of a novel ELISA.

C. Ball, Y. Mistry, G. Tarrant, 1999, Cytokine.

Temporal cascade of plasma level surges in ACTH, corticosterone, and cytokines in endotoxin-challenged rats.

I. Assenmacher, L. Givalois, J. Dornand, 1994, The American journal of physiology.

Leptin induces cyclooxygenase‐2 via an interaction with interleukin‐1β in the rat brain

Adrian F Bristow, S. Poole, G. Luheshi, 2006, The European journal of neuroscience.

Assay of Pyrogens by Interleukin‐6 Release from Monocytic Cell Lines

C. Ball, S. Poole, S. Selkirk, 1991, The Journal of pharmacy and pharmacology.

Peripheral analgesic activities of peptides related to α‐melanocyte stimulating hormone and interleukin‐1β193–195

S. Ferreira, S. Poole, B. B. Lorenzetti, 1992 .

Rat brain vascular distribution of interleukin‐1 type‐1 receptor immunoreactivity: Relationship to patterns of inducible cyclooxygenase expression by peripheral inflammatory stimuli

A. Blomqvist, S. Vigues, J. Konsman, 2004, The Journal of comparative neurology.

A novel bioassay for B-cell activating factor (BAFF) based on expression of a BAFF-receptor ectodomain-tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor-2 endodomain fusion receptor in human rhabdomyosarcoma cells.

M. Wadhwa, A. Meager, C. Ball, 2008, Journal of immunological methods.

The Second International Standard for somatropin (recombinant DNA-derived human growth hormone): preparation and calibration in an international collaborative study.

A. Jespersen, A. Bristow, 2001, Biologicals : journal of the International Association of Biological Standardization.

Collaborative study for the establishment of erythropoietin BRP batch 2.

M. Behr‐Gross, A. Daas, A. Bristow, 2004, Pharmeuropa bio.

A sialylation-sensitive cell-based in vitro bioassay for erythropoietin; incorporation of the galactose-binding Erythrina crista-galli lectin.

Adrian F Bristow, A. Heath, E. Liefooghe, 2005, Biologicals : journal of the International Association of Biological Standardization.

Consensus on How to Measure Growth Hormone in Serum

M. Ranke, G. Baumann, J. Seth, 1999, Hormone Research in Paediatrics.

Endotoxin-stimulated production of rat hypothalamic interleukin-1 beta in vivo and in vitro, measured by specific immunoradiometric assay.

P. Hagan, S. Poole, A. Bristow, 1993, Journal of molecular endocrinology.

Interleukin-1 beta production in vivo and in vitro in rats and mice measured using specific immunoradiometric assays.

S. Poole, K. Mosley, A. Bristow, 1991, Journal of molecular endocrinology.

The First International Standard for Somatropin: report of an international collaborative study.

S. Jeffcoate, R. Gaines-Das, D. Schulster, 1995, Growth regulation.

International Standards for Growth Hormone

A. Bristow, 1999, Hormone Research in Paediatrics.

Central injection of IL-10 antagonizes the behavioural effects of lipopolysaccharide in rats

R. Dantzer, N. Castanon, R. Bluthé, 1999, Psychoneuroendocrinology.

Somatropin and its variants: structural characterization and methods of analysis.

A. Bayol, M. Girard, E. Charton, 2004, Pharmeuropa bio.

Tm-Values and Unfolded Fraction Can Predict Aggregation Rates for Granulocyte Colony Stimulating Factor Variant Formulations but Not under Predominantly Native Conditions.

Paul A Dalby, Paul Matejtschuk, Adrian F Bristow, 2018, Molecular pharmaceutics.

World Health Organization International Standards for highly purified human, porcine and bovine insulins.

D. Bangham, R. E. Das, A. Bristow, 1988, Journal of biological standardization.

Rat interleukin-10: production and characterisation of biologically active protein in a recombinant bacterial expression system.

S. Vigues, C. Ball, S. Poole, 2001, European cytokine network.

Chronic restraint enhances interleukin-1-beta release in the basal state and after an endotoxin challenge, independently of adrenocorticotropin and corticosterone release.

I. Assenmacher, J. Boissin, L. Givalois, 1994, Neuroimmunomodulation.

Peripheral analgesic activities of peptides related to alpha-melanocyte stimulating hormone and interleukin-1 beta 193-195.

S. Poole, T. Smith, B. B. Lorenzetti, 1992, British journal of pharmacology.

Production of interleukin-1 receptor antagonist isoforms by microglia in mixed rat glial cells stimulated by lipopolysaccharide.

R. Dantzer, D. Verrier, P. Parnet, 2000, European cytokine network.

The rat interleukin 10 receptor: cloning and sequencing of cDNA coding for the alpha-chain protein sequence, and demonstration by western blotting of expression in the rat brain.

S. Vigues, S. Poole, A. Bristow, 2001, Cytokine.

Assignment of quantities to biological medicines: an old problem re-discovered

Adrian F Bristow, A. Bristow, 2011, Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences.

Reversible inhibition of penicillinase by quinacillin: evaluation of mechanisms involving two conformational states of the enzyme.

R. Pain, R. Virden, A. Bristow, 1978, Biochemical and Biophysical Research Communications - BBRC.

Preferential nitration with tetranitromethane of a specific tyrosine residue in penicillinase from Staphylococcus aureus PCl. Evidence that the preferentially nitrated residue is not part of the active site but that loss of activity is due to intermolecular cross-linking.

R. Virden, A. Bristow, 1978, The Biochemical journal.

The active site of penicillinase from Staphylococcus aureus PC1. Isolation of a specific covalent complex with the substrate quinacillin.

R. Pain, R. Virden, A. Bristow, 1975, The Biochemical journal.

Evaluation of Tryptic Peptides from Neisseria meningitidis Outer Membrane Proteins PorA and PorBDigestion, Peptides

C. Metcalfe, J. Wheeler, A. Bristow, 2017 .

Glycan analysis of glycoprotein pharmaceuticals: Evaluation of analytical approaches to Z number determination in pharmaceutical erythropoietin products.

Yong Zhou, C. Yuen, A. Bristow, 2011, Biologicals : journal of the International Association of Biological Standardization.