A. Chomyn

发表

Complementation and segregation behavior of disease-causing mitochondrial DNA mutations in cellular model systems.

G. Attardi, M. Yoneda, A. Chomyn, 1995, Biochimica et biophysica acta.

Regulation of mitochondrial gene expression in mammalian cells.

M. King, P. Polosa, G. Attardi, 1990, Biochemical Society transactions.

Marked replicative advantage of human mtDNA carrying a point mutation that causes the MELAS encephalomyopathy.

A. Martinuzzi, G. Attardi, O. Hurko, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Platelet-mediated transformation of mtDNA-less human cells: analysis of phenotypic variability among clones from normal individuals--and complementation behavior of the tRNALys mutation causing myoclonic epilepsy and ragged red fibers.

N. Bresolin, G. Scarlato, G. Attardi, 1994, American journal of human genetics.

Seven unidentified reading frames of human mitochondrial DNA encode subunits of the respiratory chain NADH dehydrogenase.

R. Doolittle, P. Mariottini, C. Ragan, 1986, Cold Spring Harbor symposia on quantitative biology.

Human mitochondrial leucyl-tRNA synthetase corrected mitochondrial dysfunctions due to the MELAS and diabetes associated tRNA Leu(UUR) A3243G mutation Running title: tRNA synthetase corrects mitochondrial dysfunction

Ronghua Li, M. Guan, A. Chomyn, 2010 .

A Comprehensive View of Mitochondrial Gene Expression in Human Cells

J. Montoya, S. Crews, G. Attardi, 1982 .

Platelet-mediated transformation of human mitochondrial DNA-less cells.

A. Chomyn, 1996, Methods in enzymology.

A case of mitochondrial myopathy, lactic acidosis and complex I deficiency

N. Bresolin, P. Cerretelli, T. Binzoni, 1990, Journal of Neurology.

Disruption of Fusion Results in Mitochondrial Heterogeneity and Dysfunction*

D. Chan, A. Chomyn, Hsiuchen Chen, 2005, Journal of Biological Chemistry.

Antibodies against synthetic peptides reveal that the unidentified reading frame A6L, overlapping the ATPase 6 gene, is expressed in human mitochondria

R. Doolittle, P. Mariottini, G. Attardi, 1983, Cell.

Proteolytic Processing of OPA1 Links Mitochondrial Dysfunction to Alterations in Mitochondrial Morphology*

S. Duvezin-Caubet, R. Jagasia, A. Reichert, 2006, Journal of Biological Chemistry.

Midline facial defect as a teratogenic effect of metronidazole.

Giuseppe Attardi, J. Montoya, D. Ojala, 1982 .

Mitochondrial Gene Products

G. Attardi, A. Chomyn, 1987 .

Six unidentified reading frames of human mitochondrial DNA encode components of the respiratory-chain NADH dehydrogenase

R. Doolittle, P. Mariottini, C. Ragan, 1985, Nature.

cDNA of the 24 kDa subunit of the bovine respiratory chain NADH dehydrogenase: high sequence conservation in mammals and tissue-specific and growth-dependent expression

A. Chomyn, S. A. T. Tsai Lai, 1989, Current Genetics.

Respiration and Growth Defects in Transmitochondrial Cell Lines Carrying the 11778 Mutation Associated with Leber's Hereditary Optic Neuropathy*

G. Hofhaus, G. Attardi, O. Hurko, 1996, Journal of Biological Chemistry.

In vitro genetic transfer of protein synthesis and respiration defects to mitochondrial DNA-less cells with myopathy-patient mitochondria.

N. Bresolin, G. Meola, G. Scarlato, 1991, Molecular and cellular biology.

Zidovudine induces molecular, biochemical, and ultrastructural changes in rat skeletal muscle mitochondria.

William, T. Papoian, W. Lewis, 1992, The Journal of clinical investigation.

URF6, last unidentified reading frame of human mtDNA, codes for an NADH dehydrogenase subunit.

R. Doolittle, C. Ragan, M. Riley, 1986, Science.

Identification of the polypeptides encoded in the ATPase 6 gene and in the unassigned reading frames 1 and 3 of human mtDNA.

R. Doolittle, P. Mariottini, M. Riley, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Mitochondrial Fusion Is Required for mtDNA Stability in Skeletal Muscle and Tolerance of mtDNA Mutations

T. Prolla, Yun E. Wang, J. McCaffery, 2010, Cell.

Purification of mitochondrial DNA from human cell cultures and placenta.

A. Chomyn, C. Ausenda, 1996, Methods in Enzymology.

In vivo labeling and analysis of human mitochondrial translation products.

A. Chomyn, 1996, Methods in enzymology.

MtDNA mutations in aging and apoptosis.

G. Attardi, A. Chomyn, 2003, Biochemical and biophysical research communications.

Genetic and Functional Analysis of Mitochondrial DNA‐Encoded Complex I Genes

T. Yagi, G. Attardi, Yidong Bai, 2004, Annals of the New York Academy of Sciences.

Mitochondrial Genetic Control of Assembly and Function of Complex I in Mammalian Cells

A. Chomyn, 2001, Journal of bioenergetics and biomembranes.

Mitochondrial biogenesis and genetics

G. Attardi, A. Chomyn, 1995 .

Search for differences in post-transcriptional modification patterns of mitochondrial DNA-encoded wild-type and mutant human tRNALys and tRNALeu(UUR).

C. Florentz, M. Helm, G. Attardi, 1999, Nucleic acids research.

The Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-like Episode Syndrome-associated Human Mitochondrial tRNALeu(UUR) Mutation Causes Aminoacylation Deficiency and Concomitant Reduced Association of mRNA with Ribosomes*

J. Enríquez, P. Fernández-Silva, V. Micol, 2000, The Journal of Biological Chemistry.

MtDNA mutation in MERRF syndrome causes defective aminoacylation of tRNALys and premature translation termination

J. Enríquez, G. Attardi, A. Chomyn, 1995, Nature Genetics.

MELAS mutation in mtDNA binding site for transcription termination factor causes defects in protein synthesis and in respiration but no change in levels of upstream and downstream mature transcripts.

I. Nonaka, C. Angelini, A. Martinuzzi, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Identification and mapping of human mitochondrial genes.

J. Montoya, G. Attardi, D. Ojala, 1982, Birth defects original article series.

Mitochondrial Outer Membrane Permeability Change and Hypersensitivity to Digitonin Early in Staurosporine-induced Apoptosis*

Shili Duan, G. Attardi, A. Chomyn, 2003, The Journal of Biological Chemistry.

Chapter 20 Recent advances on mitochondrial biogenesis

G. Attardi, A. Chomyn, 1992 .

Identification of a Novel Mitochondrial Complex Containing Mitofusin 2 and Stomatin-like Protein 2*

G. Attardi, Petr Hájek, Anne Chomyn, 2007, Journal of Biological Chemistry.

Heterogeneous Efficiencies of mRNA Translation in Human Mitochondria

G. Attardi, A. Chomyn, 1987 .

The site of synthesis of the iron-sulfur subunits of the flavoprotein and iron-protein fractions of human NADH dehydrogenase.

C. Ragan, G. Attardi, A. Chomyn, 1988, The Journal of biological chemistry.

Multiple deficiencies of mitochondrial DNA- and nuclear-encoded subunits of respiratory NADH dehydrogenase detected with peptide- and subunit-specific antibodies in mitochondrial myopathies.

J. Walker, H. Schägger, R. Sengers, 1995, Biochimica et biophysica acta.

Functions of the Proteins Encoded in Human Mitochondrial DNA

P. Mariottini, G. Attardi, A. Chomyn, 1987 .

Lack of Complex I Activity in Human Cells Carrying a Mutation in MtDNA-encoded ND4 Subunit Is Corrected by theSaccharomyces cerevisiae NADH-Quinone Oxidoreductase (NDI1) Gene*

A. Matsuno-Yagi, T. Yagi, G. Attardi, 2001, The Journal of Biological Chemistry.

The myoclonic epilepsy and ragged-red fiber mutation provides new insights into human mitochondrial function and genetics.

A. Chomyn, 1998, American journal of human genetics.

Antibodies against the COOH-terminal undecapeptide of subunit II, but not those against the NH2-terminal decapeptide, immunoprecipitate the whole human cytochrome c oxidase complex.

R. Doolittle, P. Mariottini, G. Attardi, 1986, The Journal of biological chemistry.

MitoTALEN: A General Approach to Reduce Mutant mtDNA Loads and Restore Oxidative Phosphorylation Function in Mitochondrial Diseases.

Marni J. Falk, M. Falk, D. Chan, 2015, Molecular therapy : the journal of the American Society of Gene Therapy.

Alignment of the amino terminal amino acid sequence of human cytochrome c oxidase subunits I and II with the sequence of their putative mRNAs.

M. Hunkapiller, G. Attardi, A. Chomyn, 1981, Nucleic acids research.

Immunoprecipitation of human mitochondrial translation products with peptide-specific antibodies.

H. Bentlage, A. Chomyn, 1996, Methods in enzymology.

Patterns of protein synthesis following heat shock in pupae of Drosophila melanogaster

H. K. Mitchell, A. Chomyn, G. Moller, 1979 .

Synthesis of the 84,000 dalton protein in normal and heat shocked Drosophila melanogaster cells as detected by specific antibody

H. K. Mitchell, A. Chomyn, 1982 .

Decreased Reactive Oxygen Species Production in Cells with Mitochondrial Haplogroups Associated with Longevity

G. Attardi, A. Chomyn, Ai Chen, 2012, PLoS ONE.

Myoclonic Epilepsy and Ragged Red Fibers (MERRF) Syndrome: Selective Vulnerability of CNS Neurons Does Not Correlate with the Level of Mitochondrial tRNAlys Mutation in Individual Neuronal Isolates

C. Miller, G. Attardi, A. Chomyn, 1997, The Journal of Neuroscience.

The mutation rate of the human mtDNA deletion mtDNA4977.

S. Tavaré, R. Shenkar, N. Arnheim, 1996, American journal of human genetics.

Skeletal muscle mitochondrial myopathy as a cause of exercise intolerance in a horse

S. Dimauro, James Jones, E. Birks, 1994, Muscle & nerve.

Purified and Protein-Loaded Mitochondrial Outer Membrane Vesicles for Functional Analysis of Preprotein Transport

G. Attardi, A. Chomyn, 2018 .

R. Burk, N. Barzilai, G. Atzmon, 2007, Mitochondrion.

Mitochondrial Fusion Is Required for mtDNA Stability in Skeletal Muscle and Tolerance of mtDNA Mutations

T. Prolla, Yun E. Wang, D. Chan, 2010, Cell.

Identification of the polypeptides encoded in the unassigned reading frames 2, 4, 4L, and 5 of human mitochondrial DNA.

R. Doolittle, P. Mariottini, B. Cottrell, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Immunoprecipitation of human NADH: ubiquinone oxidoreductase and cytochrome-c oxidase with single subunit-specific antibodies.

P. Mariottini, A. Chomyn, 1995, Methods in enzymology.