V. Byford

发表

Insights into Vitamin D metabolism using cyp24 over-expression and knockout systems in conjunction with liquid chromatography/mass spectrometry (LC/MS)

Glenville Jones, R. St-Arnaud, M. Gao, 2004, The Journal of Steroid Biochemistry and Molecular Biology.

Hepatic activation and inactivation of clinically-relevant vitamin D analogs and prodrugs.

R. Mehta, Glenville Jones, S. Strugnell, 2006, Anticancer research.

Single A326G mutation converts human CYP24A1 from 25-OH-D3-24-hydroxylase into -23-hydroxylase, generating 1α,25-(OH)2D3-26,23-lactone

Glenville Jones, B. O’Leary, M. Kaufmann, 2007, Proceedings of the National Academy of Sciences.

Altered pharmacokinetics of 1alpha,25-dihydroxyvitamin D3 and 25-hydroxyvitamin D3 in the blood and tissues of the 25-hydroxyvitamin D-24-hydroxylase (Cyp24a1) null mouse.

Glenville Jones, R. St-Arnaud, M. Demay, 2005, Endocrinology.

Target cell metabolism of 1,25-dihydroxyvitamin D3 to calcitroic acid. Evidence for a pathway in kidney and bone involving 24-oxidation.

R. Ray, G. Jones, D. Lohnes, 1989, The Biochemical journal.

Anti-proliferative activity and target cell catabolism of the vitamin D analog 1 alpha,24(S)-(OH)2D2 in normal and immortalized human epidermal cells.

R. Rice, R. Kremer, L. Degraffenried, 1996, Biochemical pharmacology.

Expression and Activity of Vitamin D-Metabolizing Cytochrome P450s (CYP1α and CYP24) in Human Nonsmall Cell Lung Carcinomas.

H. Ramshaw, Jay A. White, M. Petkovich, 1999, Endocrinology.

1 alpha,24(S)-dihydroxyvitamin D2: a biologically active product of 1 alpha-hydroxyvitamin D2 made in the human hepatoma, Hep3B.

R. Moriarty, G. Jones, S. Strugnell, 1995, The Biochemical journal.

Metabolism of a 20-methyl substituted series of vitamin D analogs by cultured human cells: apparent reduction of 23-hydroxylation of the side chain by the 20-methyl group.

A. Steinmeyer, H. Wiesinger, G. Jones, 2001, Biochemical pharmacology.

In Vitro Metabolism of the Vitamin D Analog, 22-Oxacalcitriol, Using Cultured Osteosarcoma, Hepatoma, and Keratinocyte Cell Lines (*)

R. Kremer, Glenville Jones, T. Kobayashi, 1996, The Journal of Biological Chemistry.

Use of vitamin D4 analogs to investigate differences in hepatic and target cell metabolism of vitamins D2 and D3

Glenville Jones, S. Strugnell, H. Makin, 2002 .

Unique 24-hydroxylated metabolites represent a significant pathway of metabolism of vitamin D2 in humans: 24-hydroxyvitamin D2 and 1,24-dihydroxyvitamin D2 detectable in human serum.

E. Mawer, G. Jones, H. Makin, 1998, The Journal of clinical endocrinology and metabolism.

Expression and Activity of Vitamin D-Metabolizing Cytochrome P450s (CYP1a and CYP24) in Human Nonsmall Cell Lung Carcinomas*

R. Cook, H. Ramshaw, Jay A. White, 1999 .

Dehydroepiandrosterone (DHEA) metabolism in the brain: Identification by liquid chromatography/mass spectrometry of the delta-4-isomer of DHEA and related steroids formed from androstenedione by mouse BV2 microglia

B. McEwen, K. Bulloch, Gist Croft, 2006, The Journal of Steroid Biochemistry and Molecular Biology.

Influence of 1,25-dihydroxy vitamin D3 on TLR4-induced activation of antigen presenting cells is dependent on the order of receptor engagement.

E. Petrof, Glenville Jones, Sarah Siddiqui, 2011, Immunobiology.

Use of vitamin D(4) analogs to investigate differences in hepatic and target cell metabolism of vitamins D(2) and D(3).

Glenville Jones, S. Strugnell, H. Makin, 2002, Biochimica et biophysica acta.

Metabolism of dehydroepiandrosterone by rodent brain cell lines: Relationship between 7-hydroxylation and aromatization

B. McEwen, K. Bulloch, Gist Croft, 2005, The Journal of Steroid Biochemistry and Molecular Biology.