Jianying Dong

发表

Stable IgG-like Bispecific Antibodies Directed toward the Type I Insulin-like Growth Factor Receptor Demonstrate Enhanced Ligand Blockade and Anti-tumor Activity

A. Lugovskoy, Xiufeng Wu, A. Sereno, 2010, The Journal of Biological Chemistry.

Leptin mediates postprandial increases in body temperature through hypothalamus-adrenal medulla-adipose tissue crosstalk.

G. Shulman, Xiaoyong Yang, Rachel J. Perry, 2020, The Journal of clinical investigation.

Aging-Associated Reductions in AMP-Activated Protein Kinase Activity and Mitochondrial Biogenesis

D. Befroy, G. Shulman, D. Hardie, 2007, Cell metabolism.

Syndecan-1 and -4 Synthesized Simultaneously by Mouse Mammary Gland Epithelial Cells Bear Heparan Sulfate Chains That Are Apparently Structurally Indistinguishable*

O. Goldberger, M. Bernfield, J. Deakin, 2003, The Journal of Biological Chemistry.

The role of peroxisome proliferator-activated receptor gamma coactivator-1 beta in the pathogenesis of fructose-induced insulin resistance.

G. Shulman, B. Monia, D. Weismann, 2009, Cell metabolism.

Hyperglucagonemia precedes a decline in insulin secretion and causes hyperglycemia in chronically glucose-infused rats.

G. Shulman, R. Kibbey, Dongyan Zhang, 2011, American journal of physiology. Endocrinology and metabolism.

The role of the carbohydrate response element-binding protein in male fructose-fed rats.

M. Gillum, Kisha Mitchell, G. Shulman, 2013, Endocrinology.

n-3 Fatty acids preserve insulin sensitivity in vivo in a peroxisome proliferator-activated receptor-alpha-dependent manner.

G. Shulman, G. Cline, K. Morino, 2007, Diabetes.

A Role for Mitochondrial Phosphoenolpyruvate Carboxykinase (PEPCK-M) in the Regulation of Hepatic Gluconeogenesis*

G. Shulman, M. Roden, G. Cline, 2014, The Journal of Biological Chemistry.

BIIB022, a fully human nonglycosylated γ4P antibody targeting IGF-1R for cancer therapy

Christilyn P. Graff, S. Demarest, P. Chu, 2007 .

Emerging antibody combinations in oncology

S. Demarest, K. Hariharan, Jianying Dong, 2011, mAbs.

Mitochondrial dysfunction due to long-chain Acyl-CoA dehydrogenase deficiency causes hepatic steatosis and hepatic insulin resistance

G. Shulman, G. Cline, P. A. Wood, 2007, Proceedings of the National Academy of Sciences.

Tumor-Driven Paracrine Platelet-Derived Growth Factor Receptor α Signaling Is a Key Determinant of Stromal Cell Recruitment in a Model of Human Lung Carcinoma

F. Peale, G. Frantz, N. Ferrara, 2006, Clinical Cancer Research.

VEGF‐null cells require PDGFR α signaling‐mediated stromal fibroblast recruitment for tumorigenesis

F. Peale, G. Frantz, G. Fuh, 2004, The EMBO journal.

N-acylphosphatidylethanolamine, a Gut- Derived Circulating Factor Induced by Fat Ingestion, Inhibits Food Intake

Tamas L. Horvath, Gary W. Cline, M. Gillum, 2008, Cell.

Trafficking and Proteolytic Release of Epidermal Growth Factor Receptor Ligands Are Modulated by Their Membrane-anchoring Domains*

H. Wiley, Jianying Dong, H. Wiley, 2000, The Journal of Biological Chemistry.

A stable IgG-like bispecific antibody targeting the epidermal growth factor receptor and the type I insulin-like growth factor receptor demonstrates superior anti-tumor activity

Christilyn P. Graff, Xiufeng Wu, A. Sereno, 2011, mAbs.

Combination of Two Insulin-Like Growth Factor-I Receptor Inhibitory Antibodies Targeting Distinct Epitopes Leads to an Enhanced Antitumor Response

A. Sereno, S. Demarest, E. Langley, 2010, Molecular Cancer Therapeutics.

Differential effects of interleukin-6 and -10 on skeletal muscle and liver insulin action in vivo.

G. Cline, Young-Bum Kim, You-Ree Cho, 2004, Diabetes.

The membrane-anchoring domain of epidermal growth factor receptor ligands dictates their ability to operate in juxtacrine mode.

D. Lauffenburger, H. Wiley, L. Opresko, 2005, Molecular biology of the cell.

The Membrane-anchoring Domain of EGF Receptor Ligands Dictates Their Ability to Operate in Juxtacrine Mode

D. Lauffenburger, H. Wiley, L. Opresko, 2005 .

n-3 Fatty Acids Preserve Insulin Sensitivity In Vivo in a Peroxisome Proliferator–Activated Receptor-α–Dependent Manner

G. Shulman, G. Cline, K. Morino, 2007, Diabetes.

Hormone-sensitive lipase knockout mice have increased hepatic insulin sensitivity and are protected from short-term diet-induced insulin resistance in skeletal muscle and heart.

M. Prentki, G. Shulman, G. Cline, 2005, American journal of physiology. Endocrinology and metabolism.

Adipocyte-specific overexpression of FOXC2 prevents diet-induced increases in intramuscular fatty acyl CoA and insulin resistance.

G. Shulman, D. Nilsson, G. Cline, 2005, Diabetes.

Resistance to high-fat diet-induced obesity and insulin resistance in mice with very long-chain acyl-CoA dehydrogenase deficiency.

G. Shulman, P. A. Wood, Dongyan Zhang, 2010, Cell metabolism.

Secretion from bacterial versus mammalian cells yields a recombinant scFv with variable folding properties.

F. Huang, S. Demarest, A. Capili, 2012, Archives of biochemistry and biophysics.

Inactivation of fatty acid transport protein 1 prevents fat-induced insulin resistance in skeletal muscle.

H. Lodish, G. Shulman, G. Cline, 2004, The Journal of clinical investigation.

N-3 Fatty Acids Preserve Insulin Sensitivity In Vivo in a PPARα-Dependent Manner

G. Shulman, G. Cline, K. Morino, 2007 .

Characterization of Inhibitory Anti-insulin-like Growth Factor Receptor Antibodies with Different Epitope Specificity and Ligand-blocking Properties

Christilyn P. Graff, Xiufeng Wu, A. Sereno, 2009, Journal of Biological Chemistry.

Glucose toxicity and the development of diabetes in mice with muscle-specific inactivation of GLUT4.

C. Kahn, G. Shulman, P. Perret, 2001, The Journal of clinical investigation.

The membrane-anchoring domain of epidermal growth factor receptor ligands dictates their ability to operate in juxtacrine mode.

D. Lauffenburger, L. Opresko, W. Chrisler, 2005, Molecular biology of the cell.

N-acylphosphatidylethanolamine, a Gut- Derived Circulating Factor Induced by Fat Ingestion, Inhibits Food Intake

M. Gillum, T. Horvath, G. Shulman, 2008, Cell.