M. Aust

Dual inhibition of Bcl-2 and Bcl-xL strikingly enhances PI3K inhibition-induced apoptosis in human myeloid leukemia cells through a GSK3- and Bim-dependent mechanism.

S. Grant, M. Rahmani, A. Ferreira-Gonzalez, 2013, Cancer Research.

Depletion of the chromatin remodeler CHD4 sensitizes AML blasts to genotoxic agents and reduces tumor formation.

S. Grant, M. Rahmani, C. Dumur, 2015, Blood.

PI3K/mTOR Inhibition Markedly Potentiates HDAC Inhibitor Activity in NHL Cells through BIM- and MCL-1–Dependent Mechanisms In Vitro and In Vivo

J. Friedberg, S. Grant, M. Rahmani, 2014, Clinical Cancer Research.

Inhibition of Bcl-2 antiapoptotic members by obatoclax potently enhances sorafenib-induced apoptosis in human myeloid leukemia cells through a Bim-dependent process.

S. Grant, M. Rahmani, A. Ferreira-Gonzalez, 2012, Blood.

Co-administration of the mTORC1/TORC2 inhibitor INK128 and the Bcl-2/Bcl-xL antagonist ABT-737 kills human myeloid leukemia cells through Mcl-1 down-regulation and AKT inactivation

S. Grant, M. Rahmani, C. Dumur, 2015, Haematologica.

Inhibition Of PI3K/mTOR By BEZ235 Dramatically Potentiates Panobinostat-Induced Lethality In Diffuse Large B-Cell Lymphoma Through Multiple Mechanisms

S. Grant, M. Rahmani, M. Aust, 2013 .

Dual inhibition of Bcl-2 and Bcl-xL strikingly enhances PI3K inhibition-induced apoptosis in human myeloid leukemia cells through a GSK3- and Bim-dependent mechanism.

S. Grant, M. Rahmani, A. Ferreira-Gonzalez, 2013, Cancer research.