S. Pieters

发表

Novel Pyrimidine Toll-like Receptor 7 and 8 Dual Agonists to Treat Hepatitis B Virus.

J. Vlach, F. Pauwels, E. Arnoult, 2016, Journal of medicinal chemistry.

2,4-Diaminoquinazolines as Dual Toll-like Receptor (TLR) 7/8 Modulators for the Treatment of Hepatitis B Virus.

V. Pande, F. Pauwels, T. Jonckers, 2018, Journal of medicinal chemistry.

Design and synthesis of a novel series of bicyclic heterocycles as potent γ-secretase modulators.

G. Macdonald, G. Tresadern, M. Mercken, 2012, Journal of medicinal chemistry.

Synthesis and Pharmacological Characterization of Two Novel, Brain Penetrating P2X7 Antagonists.

P. Bonaventure, N. Carruthers, Hong Ao, 2013, ACS medicinal chemistry letters.

Identification and Optimization of Pyrrolo[3,2-d]pyrimidine Toll-like Receptor 7 (TLR7) Selective Agonists for the Treatment of Hepatitis B.

F. Pauwels, T. Jonckers, E. Arnoult, 2017, Journal of medicinal chemistry.

New 2-substituted 1,2,3,4-tetrahydrobenzofuro[3,2-c]pyridine having highly active and potent central alpha 2-antagonistic activity as potential antidepressants.

J. Leysen, A. Megens, F. Bischoff, 2000, Bioorganic & medicinal chemistry letters.

2-Amino-3,4-dihydroquinazolines as inhibitors of BACE-1 (beta-site APP cleaving enzyme): Use of structure based design to convert a micromolar hit into a nanomolar lead.

Junya Qu, Allen B Reitz, Brett A Tounge, 2007, Journal of medicinal chemistry.

New 2-Substituted 1,2,3,4-Tetrahydrobenzofuro[3,2-c]pyridine Having Highly Active and Potent Central α2-Antagonistic Activity as Potential Antidepressants.

J. Leysen, A. Megens, F. Bischoff, 2000 .

Design and synthesis of a novel series of cyanoindole derivatives as potent γ-secretase modulators.

G. Macdonald, M. Mercken, S. Samanta, 2019, Bioorganic & medicinal chemistry letters.

Anilinotriazoles as potent gamma secretase modulators.

G. Macdonald, G. Tresadern, M. Mercken, 2014, Bioorganic & medicinal chemistry letters.

Discovery of selective 2,4-diaminoquinazoline toll-like receptor 7 (TLR 7) agonists.

F. Pauwels, T. Jonckers, E. Arnoult, 2018, Bioorganic & medicinal chemistry letters.