Dorien De Pooter

Novel Pyrimidine Toll-like Receptor 7 and 8 Dual Agonists to Treat Hepatitis B Virus.

J. Vlach, F. Pauwels, E. Arnoult, 2016, Journal of medicinal chemistry.

2,4-Diaminoquinazolines as Dual Toll-like Receptor (TLR) 7/8 Modulators for the Treatment of Hepatitis B Virus.

V. Pande, F. Pauwels, T. Jonckers, 2018, Journal of medicinal chemistry.

A Therapeutic Hepatitis B Virus DNA Vaccine Induces Specific Immune Responses in Mice and Non-Human Primates

J. Neefs, E. van Gulck, C. Evans, 2021, Vaccines.

Identification and Optimization of Pyrrolo[3,2-d]pyrimidine Toll-like Receptor 7 (TLR7) Selective Agonists for the Treatment of Hepatitis B.

F. Pauwels, T. Jonckers, E. Arnoult, 2017, Journal of medicinal chemistry.

Discovery of selective 2,4-diaminoquinazoline toll-like receptor 7 (TLR 7) agonists.

F. Pauwels, T. Jonckers, E. Arnoult, 2018, Bioorganic & medicinal chemistry letters.

Sustained Liver HBsAg Loss and Clonal T- and B-Cell Expansion upon Therapeutic DNA Vaccination Require Low HBsAg Levels

Lore Verschueren, Marjolein Crabbe, Dorien De Pooter, 2023, bioRxiv.

mRNA Therapeutic Vaccine for Hepatitis B Demonstrates Immunogenicity and Efficacy in the AAV-HBV Mouse Model

Soheil Pourshahian, Dorien De Pooter, Koen Dockx, 2024, Vaccines.

Robust isolation protocol for mouse leukocytes from blood and liver resident cells for immunology research

Dorien De Pooter, Koen Dockx, Nádia Conceição-Neto, 2024, PloS one.