K. Kim

发表

Carbenoxolone prevents the development of fatty liver in C57BL/6-Lep ob/ob mice via the inhibition of sterol regulatory element binding protein-1c activity and apoptosis.

C. Kim, S. B. Park, W. Jung, 2012, European journal of pharmacology.

A novel 11β-HSD1 inhibitor improves diabesity and osteoblast differentiation.

S. B. Park, W. Jung, S. Rhee, 2014, Journal of molecular endocrinology.

Protective effects of arachidonic acid against palmitic acid-mediated lipotoxicity in HIT-T15 cells

C. Kim, H. Cheon, Y. Cho, 2012, Molecular and Cellular Biochemistry.

Apoptotic Action of Peroxisome Proliferator-Activated Receptor-γ Activation in Human Non–Small-Cell Lung Cancer Is Mediated via Proline Oxidase-Induced Reactive Oxygen Species Formation

H. Cheon, J. Ahn, K. Kim, 2007, Molecular Pharmacology.

Anti-angiogenic action of PPARγ ligand in human umbilical vein endothelial cells is mediated by PTEN upregulation and VEGFR-2 downregulation

H. Cheon, J. Ahn, K. Kim, 2011, Molecular and Cellular Biochemistry.

Inhibitory effect of leptin on rosiglitazone-induced differentiation of primary adipocytes prepared from TallyHO/Jng mice.

J. Y. Kim, W. Jung, H. Cheon, 2011, Biochemical and biophysical research communications.

Phosphatase and Tensin Homolog Deleted on Chromosome 10 Suppression Is an Important Process in Peroxisome Proliferator-Activated Receptor-γ Signaling in Adipocytes and Myotubes

W. Jung, Sung Soo Kim, H. Cheon, 2007, Molecular Pharmacology.

Effects of Polyamines on TNF α-or Tamoxifen-induced Apoptosis in Human Breast Cancer Cells

Ji Young Kim, K. Ng, K. Kim, 2002 .

Toxicity Assessment of SiO2 and TiO2 in Normal Colon Cells, In Vivo and in Human Colon Organoids

S. B. Park, W. Jung, Byumseok Koh, 2020, Molecules.

Discovery and optimization of adamantane carboxylic acid derivatives as potent diacylglycerol acyltransferase 1 inhibitors for the potential treatment of obesity and diabetes.

Ji Young Kim, Dooseop Kim, S. Rhee, 2015, European journal of medicinal chemistry.

Synthesis and Diacylglycerol Acyltransferase-1 Inhibition of Azabicyclo(3.1.0)hexane Derivatives

Joo Yun Lee, D. Kim, Ji Young Kim, 2015 .

SAR Study of β-Aminoacyl-Containing Cyclic Hydrazide Derivatives as DPP-IV Inhibitors

H. Cheon, S. Rhee, J. Ahn, 2008 .

Anti-inflammatory effect of a selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor via the stimulation of heme oxygenase-1 in LPS-activated mice and J774.1 murine macrophages.

Kyoung-Jin Choi, S. B. Park, W. Jung, 2016, Journal of pharmacological sciences.

Synthesis and biological evaluation of cyclic sulfamide derivatives as 11β-hydroxysteroid dehydrogenase 1 inhibitors.

W. Jung, J. Bok, S. Rhee, 2012, ACS medicinal chemistry letters.

Identification of cyclicsulfonamide derivatives with an acetamide group as 11β-hydroxysteroid dehydrogenase 1 inhibitors.

C. Kim, N. Kang, S. Rhee, 2011, Chemical & pharmaceutical bulletin.

Synthesis and 11β hydroxysteroid dehydrogenase 1 inhibition of thiazolidine derivatives with an adamantyl group.

C. Kim, W. Jung, M. Bae, 2011, Bioorganic & medicinal chemistry letters.

Discovery of cyclicsulfonamide derivatives as 11 beta-hydroxysteroid dehydrogenase 1 inhibitors.

C. Kim, H. Cheon, S. Rhee, 2010, Bioorganic & medicinal chemistry letters.

Cyp7a1 is continuously increased with disrupted Fxr-mediated feedback inhibition in hypercholesterolemic TALLYHO/Jng mice.

W. Jung, S. Rhee, K. Kim, 2018, Biochimica et biophysica acta. Molecular and cell biology of lipids.

Optimization of Enzyme Activity Assay for Screening of Acryl CoA: Monoacylglycerol Acyltransferase 2 Inhibitors: Optimization of assay system for screening of MGAT2 inhibitors

W. Jung, S. Rhee, J. S. Park, 2015 .

Differential anti-proliferative actions of peroxisome proliferator-activated receptor-gamma agonists in MCF-7 breast cancer cells.

Sung Soo Kim, H. Cheon, K. Kim, 2006, Biochemical pharmacology.

Synthesis and biological evaluation of aminobenzimidazole derivatives with a phenylcyclohexyl acetic acid group as anti-obesity and anti-diabetic agents.

Ji Young Kim, W. Jung, S. Rhee, 2013, Bioorganic & medicinal chemistry letters.

Neuroprotective effects of KR-62980, a new PPARγ agonist, against chemical ischemia–reperfusion in SK-N-SH cells

S. H. Lee, H. Cheon, J. Ahn, 2011, Brain Research.

Synthesis and biological evaluation of pyrazoline analogues with beta-amino acyl group as dipeptidyl peptidase IV inhibitors.

Jie-Oh Lee, Sung Soo Kim, H. Cheon, 2008, European journal of medicinal chemistry.

Synthesis and biological evaluation of homopiperazine derivatives with beta-aminoacyl group as dipeptidyl peptidase IV inhibitors.

Jie-Oh Lee, Sung Soo Kim, H. Cheon, 2008, Bioorganic & medicinal chemistry letters.

Design, Synthesis, and Structure−Activity Relationship of 6-Alkynylpyrimidines as Potent Adenosine Kinase Inhibitors

A. Gomtsyan, Chih-Hung Lee, S. Bhagwat, 2002 .

Protective effects of carbenoxolone, an 11β-HSD1 inhibitor, against chemical induced dry eye syndrome

Kyoung-Jin Choi, S. B. Park, W. Jung, 2017, Apoptosis.

Fatty Liver and Insulin Resistance in the Liver-Specific Knockout Mice of Mitogen Inducible Gene-6

K. S. Kim, S. Rhee, H. Kim, 2016, Journal of diabetes research.

Anticancer effect of XAV 939 is observed by inhibiting lactose dehydrogenase A in a 3 ‐ dimensional culture of colorectal cancer cells

W. Jung, Dahee Kim, S. Rhee, 2019 .

Identification of a novel 11β-HSD1 inhibitor from a high-throughput screen of natural product extracts.

H. Jeong, S. B. Park, W. Jung, 2015, Pharmacological research.

Antiangiogenic Effect of Rosiglitazone Is Mediated via Peroxisome Proliferator-activated Receptor γ-activated Maxi-K Channel Opening in Human Umbilical Vein Endothelial Cells*

H. Cheon, Ki Young Kim, Hyae Gyeong Cheon, 2006, Journal of Biological Chemistry.

Pharmacokinetic characterization of 2-(3-benzoyl)-4-hydroxy-1,1-dioxo-2H-1,2-benzothiazine-2-yl-1-phenylethanone, a novel 11β-hydroxysteroid dehydrogenase type 1 inhibitor in rats

M. Bae, J. Song, J. Ahn, 2016, Archives of Pharmacal Research.

Pharmacokinetic characterization of 2-(3-benzoyl)-4-hydroxy-1,1-dioxo-2H-1,2-benzothiazine-2-yl-1-phenylethanone, a novel 11β-hydroxysteroid dehydrogenase type 1 inhibitor in rats

M. Bae, J. Song, J. Ahn, 2016, Archives of pharmacal research.

Anti-diabetic and anti-inflammatory effect of a novel selective 11β-HSD1 inhibitor in the diet-induced obese mice.

H. Jeong, S. B. Park, W. Jung, 2013, European journal of pharmacology.

Anti-diabetic and anti-adipogenic effects of a novel selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor, 2-(3-benzoyl)-4-hydroxy-1,1-dioxo-2H-1,2-benzothiazine-2-yl-1-phenylethanone (KR-66344).

W. Jung, H. Cheon, N. Kang, 2011, Biochemical pharmacology.

Anti-diabetic and anti-adipogenic effects of a novel selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor in the diet-induced obese mice.

W. Jung, N. Kang, S. Rhee, 2012, European journal of pharmacology.

Discovery of β-aminoacyl containing thiazolidine derivatives as potent and selective dipeptidyl peptidase IV inhibitors.

Jie-Oh Lee, Sung Soo Kim, S. Schneider, 2011, Bioorganic & medicinal chemistry letters.

Optimization of cyclic sulfamide derivatives as 11β-hydroxysteroid dehydrogenase 1 inhibitors for the potential treatment of ischemic brain injury.

S. B. Park, W. Jung, J. H. Lee, 2019, Bioorganic & medicinal chemistry letters.

Protective effects of arachidonic acid against palmitic acid-mediated lipotoxicity in HIT-T15 cells

C. Kim, H. Cheon, Y. Cho, 2012, Molecular and Cellular Biochemistry.

Anticancer effect of XAV939 is observed by inhibiting lactose dehydrogenase A in a 3-dimensional culture of colorectal cancer cells

W. Jung, Dahee Kim, Byumseok Koh, 2019, Oncology letters.

Optimization of Benzimidazole Scaffold with a trans‐Phenylcyclohexyl Acetic Acid as Diacylglycerol Acyltransferase‐1 Inhibitors

J. H. Oh, Ji Young Kim, W. Jung, 2017 .

Inhibitory effect of leptin on rosiglitazone-induced differentiation of primary adipocytes prepared from TallyHO/Jng mice.

J. Y. Kim, W. Jung, H. Cheon, 2011, Biochemical and biophysical research communications.