Guoyi Yan

发表

Discovery and biological evaluation of darolutamide derivatives as inhibitors and down-regulators of wild-type AR and the mutants.

Xinghai Li, Mingxing Hu, J. Yu, 2019, European journal of medicinal chemistry.

Predictive significance of tumor budding in postoperative liver metastasis of pancreatic neuroendocrine tumors

Deyu Li, Senmao Mu, Guoyi Yan, 2020, Journal of surgical oncology.

LncRNA MAPKAPK5_AS1 facilitates cell proliferation in hepatitis B virus -related hepatocellular carcinoma

Deyu Li, Guoyi Yan, L. Tao, 2022, Laboratory Investigation.

Synthesis and biological evaluation of 4-(1,2,3-triazol-1-yl)coumarin derivatives as potential antitumor agents.

Zhi Li, Meng Zhou, Hao Luo, 2014, Bioorganic & medicinal chemistry letters.

Analysis of furo[3,2-c]tetrahydroquinoline and pyrano[3,2-c]tetrahydroquinoline derivatives as antitumor agents and their metabolites by liquid chromatography/electrospray ionization tandem mass spectrometry.

Gu He, Meng Zhou, Hao Luo, 2013, Rapid communications in mass spectrometry : RCM.

Design, synthesis and biological evaluation of indole derivatives as Vif inhibitors.

Yong-tang Zheng, Rong-Hua Luo, Rui Li, 2017, Bioorganic & medicinal chemistry letters.

Discovery of a novel covalent CDK4/6 inhibitor based on palbociclib scaffold.

Xinyu R. Ma, Yuanyuan Liu, Jie Yang, 2021, European journal of medicinal chemistry.

Discovery of 2-Methyl-2-(4-(2-methyl-8-(1H-pyrrolo[2,3-b]pyridin-6-yl)-1H-naphtho[1,2-d]imidazol-1-yl)phenyl)propanenitrile as a Novel PI3K/mTOR Inhibitor with Enhanced Antitumor Efficacy In Vitro and In Vivo.

Rui Li, Yuanyuan Liu, Jie Yang, 2022, Journal of medicinal chemistry.

Anti-CD133 Antibody-Targeted Therapeutic Immunomagnetic Albumin Microbeads Loaded with Vincristine-Assisted to Enhance Anti-Glioblastoma Treatment.

P. Lu, Yongxia Zhu, Yuqi Guo, 2019, Molecular pharmaceutics.

Identification of hit compounds for squalene synthase: Three‐dimensional quantitative structure‐activity relationship pharmacophore modeling, virtual screening, molecular docking, binding free energy calculation, and molecular dynamic simulation

J. Shi, Meng Zhou, Rui Li, 2017 .

Synthesis and biological evaluation of novel 2,3-dihydrochromeno[3,4-d]imidazol-4(1H)-one derivatives as potent anticancer cell proliferation and migration agents.

Meng Zhou, Rui Li, Guoyi Yan, 2016, European journal of medicinal chemistry.

Synthesis, biological evaluation and molecular docking study of N-(2-methoxyphenyl)-6-((4-nitrophenyl)sulfonyl)benzamide derivatives as potent HIV-1 Vif antagonists.

Yong-tang Zheng, Ruirui Wang, Rong-Hua Luo, 2017, European journal of medicinal chemistry.

Design, Synthesis and Biological Evaluation of 4, 6-Coumarin Derivatives as Anti-Cancer and Apoptosis-Inducing Agents.

Meng Zhou, Rui Li, Guoyi Yan, 2021, Anti-cancer agents in medicinal chemistry.

Design, Synthesis, and Biological Evaluation of Dimorpholine Substituted Thienopyrimidines as Potential Class I PI3K/mTOR Dual Inhibitors.

Lifeng Zhao, Guoyi Yan, Yufang Deng, 2017, Journal of medicinal chemistry.

Discovery and biological evaluation of novel androgen receptor antagonist for castration-resistant prostate cancer.

J. Yu, Xinghai Li, Guoyi Yan, 2019, European journal of medicinal chemistry.

Synthesis and biological evaluation of (E)-4-(3-arylvinyl-1H-indazol-6-yl)pyrimidin-2-amine derivatives as PLK4 inhibitors for the treatment of breast cancer

Q. Lei, Tinghong Ye, Ningyu Wang, 2017 .

Discovery of 4-phenyl-2H-benzo[b][1,4]oxazin-3(4H)-one derivatives as potent and orally active PI3K/mTOR dual inhibitors.

Rui Li, Lifeng Zhao, Jie Yang, 2019, European journal of medicinal chemistry.

Metabolically Stable Diphenylamine Derivatives Suppress Androgen Receptor and BET Protein in Prostate Cancer.

Xinghai Li, J. Yu, Guoyi Yan, 2020, Biochemical pharmacology.

Identification of critical pathways and potential therapeutic targets in poorly differentiated duodenal papilla adenocarcinoma

Yuqi Guo, Deyu Li, Senmao Mu, 2020, Cancer cell international.

Discovery of a PROTAC targeting ALK with in vivo activity.

Jie Yang, Meng Zhou, Rui Li, 2021, European journal of medicinal chemistry.

Discovery of a novel class of pyridine derivatives that selectively inhibits mutant isocitrate dehydrogenase 2

Yinglan Zhao, Lifeng Zhao, Mingxing Hu, 2018, Chemical biology & drug design.

Identification of Critical Pathways and Potential Key Genes in Poorly Differentiated Pancreatic Adenocarcinoma

Fangyuan Qin, Y. Zhai, Senmao Mu, 2021, OncoTargets and therapy.

Selective degradation of PARP2 by PROTACs via recruiting DCAF16 for triple-negative breast cancer.

Rui Li, Hongjia Zhang, Xinyu R. Ma, 2022, European journal of medicinal chemistry.

Design, synthesis, and biological evaluation of 2-amino-N-(2-methoxyphenyl)-6-((4-nitrophenyl)sulfonyl)benzamide derivatives as potent HIV-1 Vif inhibitors.

Yong-tang Zheng, Rong-Hua Luo, Rong-hong Zhang, 2019, Bioorganic & medicinal chemistry letters.

Pharmacophore‐based virtual screening, molecular docking, molecular dynamics simulation, and biological evaluation for the discovery of novel BRD4 inhibitors

Rui Li, Guoyi Yan, Suke Lan, 2018, Chemical biology & drug design.

Assessing the performance of docking scoring function, FEP, MM-GBSA, and QM/MM-GBSA approaches on a series of PLK1 inhibitors.

Jianyou Shi, Rui Li, Guoyi Yan, 2017, MedChemComm.

Identification of HDAC6 selective inhibitors: pharmacophore based virtual screening, molecular docking and molecular dynamics simulation

Yuqi Guo, Fangyuan Qin, Xueqing Wang, 2020, Journal of biomolecular structure & dynamics.

Assessing the performance of docking scoring function, FEP, MM-GBSA, and QM/MM-GBSA approaches on a series of PLK1 inhibitors.

Jianyou Shi, Rui Li, Guoyi Yan, 2017, MedChemComm.

Gu He, Meng Zhou, Hao Luo, 2013, Rapid communications in mass spectrometry : RCM.

Synthesis and biological evaluation of 3-(1,3,4-oxadiazol-2-yl)-1,8-naphthyridin-4(1H)-ones as cisplatin sensitizers.

Hao Luo, Rui Li, Guoyi Yan, 2018, MedChemComm.