Meizhong Jin

发表

Androgen receptor degradation by the proteolysis-targeting chimera ARCC-4 outperforms enzalutamide in cellular models of prostate cancer drug resistance

C. Crews, T. Neklesa, D. McDonnell, 2018, Communications Biology.

Discovery of an Orally Efficacious Imidazo[5,1-f][1,2,4]triazine Dual Inhibitor of IGF-1R and IR.

D. Werner, P. Gokhale, E. May, 2010, ACS medicinal chemistry letters.

Palladium-catalyzed direct heck arylation of dual pi-deficient/pi-excessive heteroaromatics. Synthesis of C-5 arylated imidazo[1,5-a]pyrazines.

V. Snieckus, A. Crew, J. McCubbin, 2008, Organic letters.

A highly effective one-pot synthesis of quinolines from o-nitroarylcarbaldehydes.

M. Cox, Qinghua Weng, D. Werner, 2007, Organic & biomolecular chemistry.

Total synthesis of (+)-peloruside A.

Richard E. Taylor, Meizhong Jin, 2005, Organic letters.

Toward a total synthesis of peloruside A: enantioselective preparation of the C8-C19 region.

Richard E. Taylor, Meizhong Jin, 2003, Organic letters.

Imidazo[1,5-a]pyrazines: orally efficacious inhibitors of mTORC1 and mTORC2.

D. Werner, P. Gokhale, N. Gibson, 2011, Bioorganic & medicinal chemistry letters.

Small-molecule ATP-competitive dual IGF-1R and insulin receptor inhibitors: structural insights, chemical diversity and molecular evolution.

Jing Wang, E. Buck, M. Mulvihill, 2012, Future medicinal chemistry.

Modulation of Insulin-Like Growth Factor-1 Receptor and its Signaling Network for the Treatment of Cancer: Current Status and Future Perspectives

E. Buck, M. Mulvihill, Meizhong Jin, 2013, Oncology reviews.

Discovery of potent, selective and orally bioavailable imidazo[1,5-a]pyrazine derived ACK1 inhibitors.

D. Epstein, Jing Wang, A. Crew, 2013, Bioorganic & medicinal chemistry letters.

Discovery of novel insulin-like growth factor-1 receptor inhibitors with unique time-dependent binding kinetics.

P. Gokhale, D. Epstein, E. May, 2013, ACS medicinal chemistry letters.

The Discovery of Dual IGF‐1R and IR Inhibitor FQIT for the Treatment of Cancer

E. Buck, M. Mulvihill, Meizhong Jin, 2012 .

Furo[3,2-C]pyridines

Hanqing Dong, Xin Chen, Meizhong Jin, 1974 .

Androgen receptor degradation by the proteolysis-targeting chimera ARCC-4 outperforms enzalutamide in cellular models of prostate cancer drug resistance

C. Crews, T. Neklesa, D. McDonnell, 2018, Communications Biology.

Novel 6-aminofuro[3,2-c]pyridines as potent, orally efficacious inhibitors of cMET and RON kinases.

M. Albertella, P. Gokhale, D. Epstein, 2013, Bioorganic & medicinal chemistry letters.

Potent and selective cyclohexyl-derived imidazopyrazine insulin-like growth factor 1 receptor inhibitors with in vivo efficacy.

P. Gokhale, K. Foreman, Hanqing Dong, 2011, Bioorganic & medicinal chemistry letters.